Parent-adolescent conflict: an exploration from the perspective of Vietnamese adolescents.

This research investigates parent-adolescent conflicts from the viewpoint of Vietnamese adolescents. Employing a mixed-method approach, the study conducted in-depth interviews and a questionnaire survey with 706 high-school students. The findings highlight that conflicts between Vietnamese parents and adolescents commonly arise regarding internet usage for entertainment and academic purposes. Furthermore, adolescents reported having more conflicts with their mothers than with their fathers. Although instances of parental aggression were identified, most adolescents perceived their parents' conflict resolution as supportive. However, Vietnamese adolescents tended to display passive behavioral responses during conflicts. The research also identified certain emotional responses as warning signs of mental health issues, including suicidal thoughts, among some adolescents. Moreover, a higher frequency of conflicts with parents was significantly associated with increased peer connections. The study emphasizes the importance of professionals, such as school social workers or counselors, prioritizing the understanding of parent-child conflicts' impact on adolescents' emotions and mental health. Additionally, it underscores the significance of examining parenting patterns and parent-child communication within contemporary Vietnamese families.

Reassessing the most popularly suggested measurement models and measurement invariance of the Maslach Burnout Inventory - human service survey among Vietnamese healthcare professionals.

BACKGROUND: Despite its popularity, Maslach Burnout Inventory-Human Service Survey (MBI-HSS)'s factorial structure has been subject to considerable debate, and its measurement invariance (MI) is seldomly examined. This cross-sectional study aims at reassessing the most popularly suggested structures of this instrument, namely the 20- and 22-item three-factor model on Vietnamese healthcare professionals. It also examines the MI of MBI-HSS across genders, occupations, and mental health conditions. METHOD: Self-administered questionnaires were sent out to 1500 doctors and nurses working at 15 hospitals in big cities in Vietnam in September and October 2020, and 1162 valid questionnaires were collected. The questionnaire consists of three sets of questions covering (1) demographic information of participants; (2) MBI-HSS questionnaire; and (3) The 21-item version of the Depression-Anxiety-Stress Scale. MBI-HSS scale was validated on Vietnamese sample for the first time; therefore, we used the repeated forward-backward procedure to translate this scale into Vietnamese. To examine which model best fits the data, a series of Confirmatory Factor Analysis (CFA) was used to test the model fit of correlated three-factor model, second-order hierarchical model, and bi-factor model. The reliability of the MBI-HSS was assessed using Cronbach's α coefficients. Then, multiple-group CFA (MGCFA) was applied to determine whether the MBI-HSS has a similar structure between groups different in gender, occupation, and mental health condition. RESULTS: Our findings confirmed that the 22-item MBI-HSS best fit the data, and this scale measures three distinct but related aspects of burnout, including Emotional Exhaustion, Depersonalization, and Personal Accomplishment. The MI of MBI-HSS across genders and occupations was also confirmed. However, data did not fit well with group at risk for common mental health disorders. It can be concluded that the Vietnamese version of MBI-HSS is a valid measure to assess burnout level of healthcare professionals in Vietnam who are not at risk for mental health disorders.

The mediating role of self-compassion between proactive coping and perceived stress among students.

Proactive coping has been documented as a significant predictor of perceived stress. When facing stressful events, the more individuals use proactive coping strategies, the lower their stress level will be. However, there is still little research of possible latent factors participating in this relationship to explain how proactive coping can reduce of perceived stress, directly and indirectly. This study aimed to examine whether self-compassion can mediate the relationship between proactive coping and perceived stress among students. In a cross-sectional study carried out in 2019, we invited 384 undergraduate students in Hanoi (Vietnam) to voluntarily complete a self-report questionnaire that measured proactive coping, self-compassion and perceived stress scale. Results showed that proactive coping was positively related to level of self-compassion, and both proactive coping and self-compassion were negatively related to stress scores. The effect of proactive coping on stress was eliminated when self-compassion was controlled, showing the mediating role of self-compassion in the relationship between proactive coping and perceived stress score. Furthermore, among six factors contributing to the concept of self-compassion, data documented mediating role of "self-kindness,""self-judgment," and "mindfulness" while no mediating role of "common humanity,""isolation," and "over-identification" was observed. Among three mediating factors, mindfulness appeared to be the most important factor explaining the relationship between proactive coping and perceived stress. These results consolidate existing literature of the protective role of self-compassion on psychological health, and hence provide more support for the application of self-compassion, especially of mindfulness, in working with people with stress.

Development of a kinetic model expressing anomalous phenomena in human induced pluripotent stem cell culture.

During culture with feeder cells, deviation from the undifferentiated state of human induced pluripotent stem cells (hiPSCs) occurs at a very low frequency. Anomalous cell migration in central and peripheral regions of hiPSC colonies has been suggested to be the trigger for this phenomenon. To confirm this hypothesis, sequential cell migration prior to deviation must be demonstrated. This has been difficult using in vitro methods. We therefore developed a kinetic model with a proposed definition of anomalous cell migration as continuous relatively fast or slow cell migration. The developed model was validated via in silico reproduction of deviation phenomenon observed in vitro, such as the positions of deviated cells in a colony and the frequency of deviation in culture. This model suggests that anomalous cell migration-driven hiPSC deviation can be explained by two factors: a mechanical stimulus, represented by cell migration, and duration of the mechanical stimulus. The factor "duration of mechanical stimulus" sets our model apart from others, and helps to realize the ultra-rare trigger (approximately 10-5) of deviation from the undifferentiated state in hiPSC culture.

Elucidation of human induced pluripotent stem cell behaviors in colonies based on a kinetic model.

Maintaining the homogeneity of a stem cell population is one of the challenges in bioprocessing prior to therapeutic applications of stem cells. Concerning human induced pluripotent stem cell (hiPSC) colonies cultured on feeder cells, cells at the peripheral region of the colony were found to have a higher average movement rate than cells at the central region of the colony. This spatial difference in average movement rate might lead to spatial heterogeneity of cell fate decision in the colony. We have developed a kinetic model to clarify the origin of this phenomenon which was difficult to understand by in vitro studies alone. Using a kinetic model based on a cellular automaton, we described fundamental cell behaviors including cell division, contact inhibition, cell migration, cell-cell connections, and cell-substrate connections. With all parameter values estimated from experimental data, the appropriateness of our kinetic model was indicated by good agreement between simulated and experimental data. Using the kinetic model, the average cell movement rate in a colony became homogenous after cell division stopped, implying that cell division was the main cause of the observed spatial heterogeneity. The result also showed a directly proportional relationship between the frequency of cell pushing and cell movement rate in the colony, confirming the role of cell division. Our kinetic model is expected to be useful for studying behaviors of hiPSCs and proposing good strategies to improve hiPSC bioprocessing.