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Med Eng Phys ; 35(8): 1105-15, 2013 Aug.
Article in English | MEDLINE | ID: mdl-23273484

ABSTRACT

This paper presents an innovative approach for T-wave peak detection and subsequent T-wave end location in 12-lead paced ECG signals based on a mathematical model of a skewed Gaussian function. Following the stage of QRS segmentation, we establish search windows using a number of the earliest intervals between each QRS offset and subsequent QRS onset. Then, we compute a template based on a Gaussian-function, modified by a mathematical procedure to insert asymmetry, which models the T-wave. Cross-correlation and an approach based on the computation of Trapezium's area are used to locate, respectively, the peak and end point of each T-wave throughout the whole raw ECG signal. For evaluating purposes, we used a database of high resolution 12-lead paced ECG signals, recorded from patients with ischaemic cardiomyopathy (ICM) in the University Hospitals of Leicester NHS Trust, UK, and the well-known QT database. The average T-wave detection rates, sensitivity and positive predictivity, were both equal to 99.12%, for the first database, and, respectively, equal to 99.32% and 99.47%, for QT database. The average time errors computed for T-wave peak and T-wave end locations were, respectively, -0.38±7.12 ms and -3.70±15.46 ms, for the first database, and 1.40±8.99 ms and 2.83±15.27 ms, for QT database. The results demonstrate the accuracy, consistency and robustness of the proposed method for a wide variety of T-wave morphologies studied.


Subject(s)
Cardiomyopathies/diagnosis , Diagnosis, Computer-Assisted/methods , Electrocardiography/methods , Heart Rate , Myocardial Ischemia/diagnosis , Pattern Recognition, Automated/methods , Algorithms , Cardiomyopathies/etiology , Cardiomyopathies/physiopathology , Humans , Myocardial Ischemia/complications , Myocardial Ischemia/physiopathology , Reproducibility of Results , Sensitivity and Specificity
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