1.
J Dermatol
; 45(6): e165-e166, 2018 Jun.
Article
in English
| MEDLINE
| ID: mdl-29265490
Subject(s)
Blood Component Transfusion/methods , Plasma , Protein C Deficiency/complications , Purpura Fulminans/therapy , Thrombomodulin/administration & dosage , Female , Humans , Infant, Newborn , Mutation, Missense , Protein C/genetics , Protein C Deficiency/diagnosis , Protein C Deficiency/genetics , Purpura Fulminans/diagnosis , Purpura Fulminans/etiology , Treatment Outcome
2.
Intern Med
; 54(17): 2213-7, 2015.
Article
in English
| MEDLINE
| ID: mdl-26328649
ABSTRACT
We report a case involving a 43-year-old Japanese woman with steroid-resistant focal segmental glomerular sclerosis (FSGS) and severe renal dysfunction, which was ameliorated by low-density lipoprotein apheresis (LDL-A). She had been treated with steroid therapy, but had experienced anuria for over 10 weeks and required hemodialysis. She was then treated with LDL-A, which resulted in improved urinary protein excretion and renal function. Her renal function recovered after 97 days of hemodialysis therapy. This case suggests that LDL-A may represent an effective rescue treatment in patients with FSGS and long-term anuria.