Impact of financial toxicity on adults with cancer during the COVID-19 pandemic: an integrative review.

OBJECTIVES: to identify the repercussions of financial toxicity on the lives of adult cancer patients during the COVID-19 pandemic. METHODS: an integrative review was conducted using the PubMed, Web of Science, Scopus, and Embase databases, as well as the Virtual Health Library portal, in March 2023. RESULTS: out of 62 studies found, 13 were included for analysis. The primary repercussions of financial toxicity included difficulties in covering basic expenses such as food, housing, medication, transportation, and internet access; increased anxiety and concerns related to health and financial situations; reduction or absence of income; challenges in obtaining treatment or accessing healthcare services; rising expenses; and telemedicine as a less burdensome alternative. CONCLUSIONS: the pandemic has exacerbated financial toxicity; therefore, healthcare teams must recognize it as an adverse event of oncological treatment and understand its potential to affect various aspects of patients' lives.

Anxiety Levels in Brazilian Women with Metastatic Breast Cancer Undergoing Palliative Chemotherapy: A Prospective Study.

OBJECTIVE: This study aimed to assess anxiety levels among women with metastatic breast cancer undergoing palliative chemotherapy. METHODS: A descriptive, prospective study was conducted at an oncology hospital in southern Brazil from September 2021 to October 2022. A total of 123 adult women receiving outpatient palliative chemotherapy were included in the study. Anxiety levels were evaluated using the State-Trait Anxiety Inventory at baseline, the fifth week, and the eleventh week of treatment. Data were analyzed using Kruskal-Wallis, Mann-Whitney, and Multiple General Regression Models. RESULTS: Women with advanced breast cancer had an average trait-anxiety score of 48.24±5.92. A progressive improvement in anxiety scores was observed throughout the treatment evaluation stages (44.90±5.89; 43.37±5.34; 42.58±5.75), with a significant difference between the evaluations (p=0.008). Significant correlations were found between trait-anxiety and work situation (p=0.010) and ovarian metastasis (p=0.022). The adjusted general regression model also showed statistical significance for baseline evaluation with offspring (p=0.045) and education level (p=0.041). CONCLUSION: Women with breast cancer undergoing palliative chemotherapy exhibited high trait-anxiety scores, which decreased significantly over the course of treatment.

Sinonasal Cancer Cases in a Nationwide Hospital Cancer Registry in Brazil, 2007-2021.

BACKGROUND: Sinonasal cancers (SNC) are rare cancers with a high proportion attributable to occupational carcinogens. This study aims to describe the sociodemographic, clinical, and occupational characteristics of subjects with SNC in Brazil. METHODS: Observational study conducted with secondary data from a network of Hospital Cancer Registries. We selected epithelial/unspecified SNC records with a year of diagnosis from 2007 to 2021. We performed descriptive statistics of SNC cases and calculated crude and age-standardized rates (ASR, standard: world population) by gender and Region of residence. RESULTS: We identified 2,384 cases, 1,553 (65.1%) in men and 831 (34.9%) in women. The mean age at diagnosis was 59 years for both. Most SNC (50.7% in men and 53.2% in women) originated from the maxillary sinus. Most (65.5% in men and 54.5% in women) were squamous cell carcinomas. Information on occupation was missing in the years 2019-2021. Most male SNC patients (44.8%) were employed in group 6 (Agricultural, forestry, and fishing workers), while women had been mainly (34.6%) working in groups 8 (Workers in the production of industrial goods and services, machine operators) and in group 6 (27.6%). Crude SNC incidence rates were 1.0 per million person-years in men and 0.5 in women, while ASR were 1.0 and 0.4, respectively. In both genders, the highest ASR was in Minas Gerais (men: 1.9; women: 0.7). CONCLUSIONS: Establishing the profile of Brazilians with sinonasal cancer can stimulate epidemiologic research for monitoring this group of cancers with a high association with occupational exposures.

Toxicidad financiera y calidad de vida relacionada con la salud en pacientes con cáncer: un estudio correlacional / Financial Toxicity and Health-Related Quality of Life Among Cancer Patients: A Correlational Study / Toxicidade financeira e qualidade de vida relacionada à saúde de pacientes com câncer: estudo correlacional

Introducción: la toxicidad financiera puede aumentar los costes en salud, así como impactar negativamente en la adherencia terapéutica y en la calidad de vida relacionada con la salud de los pacientes con cáncer en el sistema público de salud. Objetivo: correlacionar la toxicidad financiera con la calidad de vida relacionada con la salud de adultos con cáncer durante la pandemia covid-19. Materiales y método: estudio observacional, transversal y correlacional con 179 pacientes atendidos por el Sistema Único de Salud en una capital del sur de Brasil. La recolección de datos se realizó de septiembre de 2021 a diciembre de 2022, utilizando cuestionarios con datos sociodemográficos y clínicos, y el COmprehensive Score for Financial Toxicity y la Functional Assessment of Cancer Therapy-General. La correlación entre la toxicidad financiera y la calidad de vida relacionada con la salud se evaluó mediante el coeficiente de correlación de Spearman a un nivel de significación del 5 %. Resultados: la correlación entre la toxicidad financiera y la calidad de vida relacionada con la salud fue de 0,41 (valor p < 0,001). Las puntuaciones de toxicidad económica y calidad de vida relacionada con la salud fueron 20,1/44 y 73,3/108, respectivamente. Conclusión: este estudio reveló que cuanto menor era la toxicidad financiera, mejor era la calidad de vida relacionada con la salud de los pacientes. En este sentido, reconocer la presencia de toxicidad financiera en el itinerario terapéutico podría ayudar a mejorar la adherencia al tratamiento y la calidad de vida relacionada con la salud.

Introdução: a toxicidade financeira pode elevar os custos com cuidados em saúde, além de impactar negativamente a adesão terapêutica e a qualidade de vida relacionada à saúde dos pacientes com câncer no âmbito do sistema público de saúde. Objetivo: correlacionar a toxicidade financeira com a qualidade de vida relacionada à saúde de adultos com câncer durante a pandemia da covid-19. Materiais e método: estudo observacional, transversal, correlacional com 179 pacientes atendidos pelo Sistema Único de Saúde, em uma capital do sul do Brasil. A coleta de dados ocorreu de setembro de 2021 a dezembro de 2022, utilizando questionários com dados sociodemográficos e clínicos, e o COmprehensive Score for Financial Toxicity e o Functional Assessment of Cancer Therapy-General. A correlação entre toxicidade financeira e qualidade de vida relacionada à saúde foi avaliada com o coeficiente de correlação de Spearman a um nível de significância de 5 %. Resultados: a correlação entre a toxicidade financeira e a qualidade de vida relacionada à saúde foi de 0,41 (p-valor < 0,001). O escore de toxicidade financeira e de qualidade de vida relacionada à saúde foi de 20,1/44 e 73,3/108, respectivamente. Conclusão: este estudo revelou que, quanto menor a toxicidade financeira, melhor a qualidade de vida relacionada à saúde dos pacientes. Nesse sentido, reconhecer a presença da toxicidade financeira no itinerário terapêutico poderá contribuir para melhorar a adesão ao tratamento e a qualidade de vida relacionada à saúde.

Introduction: Financial toxicity can increase healthcare costs, in addition to negatively impacting the therapeutic adherence and health- related quality of life of cancer patients within the public healthcare system. Objective: To correlate financial toxicity with the adults living with cancer health-related quality of life during the COVID-19 pandemic. Materials and Methods: This is an observational, cross-sectional, correlational study conducted with 179 patients receiving care from the Unified Health System in a capital city in southern Brazil. Data collection was performed from September 2021 to December 2022, using questionnaires containing sociodemographic and clinical data, and the Comprehensive Score for Financial Toxicity and the Functional Assessment of Cancer Therapy-General. The correlation between financial toxicity and health-related quality of life was assessed using Spearman's correlation coefficient at a 5 % significance level. Results: The correlation between financial toxicity and health-related quality of life was 0.41 (p-value < 0.001). The financial toxicity and health-related quality of life scores were 20.1/44 and 73.3/108, respectively. Conclusion: This study has found that the lower the financial toxicity, the better the patients' health-related quality of life. In this sense, recognizing the presence of financial toxicity in the treatment course could help improve adherence to treatment and health-related quality of life.

Qualidade de vida no transplante de células-tronco hematopoéticas na pandemia da Covid-19: série de casos / Quality of life in hematopoietic stem cell transplantation during the Covid-19 pandemic: case series

O Transplante de Células Tronco Hematopoéticas, é um tratamento complexo, com a finalidade curativa de doenças malignas e benignas, que afeta diretamente a qualidade de vida dos pacientes e cuidadores. Estudos anteriores ao período pandêmico apresentaram aspectos da sobrecarga do cuidador e qualidade de vida de ambos, esta pesquisa presente contribui para esta lacuna sobre a temática durante a pandemia. Avaliar e correlacionar a qualidade de vida de transplantados de células-tronco hematopoéticas com a qualidade de vida e sobrecarga dos cuidadores durante à pandemia de COVID-19. Série de casos com 16 díades, realizada num hospital público do Brasil, referência na América Latina. A qualidade de vida dos transplantados foi avaliada com o Functional Assessment Cancer Therapy-Bone Marrow Transplantation, já dos cuidadores com o Medical Outcomes Studt 36-Item Short Form Health Survey, a sobrecarga com o Zarit Burden Interview. Observou-se menor percepção no bem-estar funcional dos transplantados e pior estado geral de saúde dos cuidadores; a saúde mental do cuidador interferiu em diferentes domínios da qualidade de vida; houve correlação negativa entre a qualidade de vida e sobrecarga do cuidador. A pandemia impactou na qualidade de vida das díades; há necessidade de suporte adicional tanto para o paciente, quanto para o cuidador.

Hematopoietic Stem Cell Transplantation is a complex treatment, aimed at curing malignant and benign diseases, which directly affects the quality of life of patients and caregivers. Studies prior to the pandemic period presented aspects of caregiver burden and quality of life for both; this current research contributes to this gap on the topic during the pandemic. To evaluate and correlate the quality of life of hematopoietic stem cell transplant recipients with the quality of life and caregiver burden during the COVID-19 pandemic. Case series with 16 dyads, carried out in a public hospital in Brazil, a reference in Latin America. The quality of life of transplant recipients was assessed with the Functional Assessment Cancer Therapy-Bone Marrow Transplantation, caregivers with the Medical Outcomes Studt 36-Item Short Form Health Survey, burden with the Zarit Burden Interview. There was a lower perception of the functional well-being of transplant recipients and a worse general health status of caregivers; the caregiver's mental health interfered in different domains of quality of life; there was a negative correlation between quality of life and caregiver burden. The pandemic impacted the dyads' quality of life; there is a need for additional support for both the patient and the caregiver.

Impact of financial toxicity on adults with cancer during the COVID-19 pandemic: an integrative review / Repercusiones de la toxicidad financiera en adultos con cáncer durante la pandemia de COVID-19: revisión integrativa / Repercussões da toxicidade financeira em adultos com câncer durante a pandemia da COVID-19: revisão integrativa

ABSTRACT Objectives: to identify the repercussions of financial toxicity on the lives of adult cancer patients during the COVID-19 pandemic. Methods: an integrative review was conducted using the PubMed, Web of Science, Scopus, and Embase databases, as well as the Virtual Health Library portal, in March 2023. Results: out of 62 studies found, 13 were included for analysis. The primary repercussions of financial toxicity included difficulties in covering basic expenses such as food, housing, medication, transportation, and internet access; increased anxiety and concerns related to health and financial situations; reduction or absence of income; challenges in obtaining treatment or accessing healthcare services; rising expenses; and telemedicine as a less burdensome alternative. Conclusions: the pandemic has exacerbated financial toxicity; therefore, healthcare teams must recognize it as an adverse event of oncological treatment and understand its potential to affect various aspects of patients' lives.

RESUMEN Objetivos: identificar las repercusiones de la toxicidad financiera en la vida de pacientes adultos con cáncer durante la pandemia de COVID-19. Métodos: revisión integrativa realizada en las plataformas de datos PubMed, Web of Science, Scopus, Embase y en el portal de la Biblioteca Virtual en Salud en marzo de 2023. Resultados: de 62 estudios encontrados, 13 fueron incluídos para análisis. Las principales repercusiones de la toxicidad financiera fueron: dificultades para cubrir gastos básicos como alimentación, vivienda, medicamentos, transporte e internet; aumento de la ansiedad y preocupaciones relacionadas con la salud y la situación financiera; reducción o ausencia de ingresos; dificultad para obtener tratamiento o acceso a los servicios de salud; aumento de los gastos y telemedicina como alternativa menos costosa. Conclusiones: la pandemia ha intensificado la toxicidad financiera; por lo tanto, los equipos de salud necesitan reconocerla como un evento adverso del tratamiento oncológico y comprender que puede afectar diferentes ámbitos de la vida de los pacientes.

RESUMO Objetivos: identificar as repercussões da toxicidade financeira na vida de pacientes adultos com câncer durante a pandemia da COVID-19. Métodos: revisão integrativa realizada nas plataformas de dados PubMed, Web of Science, Scopus, Embase e no portal da Biblioteca Virtual em Saúde no mês de março de 2023. Resultados: de 62 estudos encontrados, 13 foram incluídos para análise. As principais repercussões da toxicidade financeira foram: dificuldades em custear despesas básicas como alimentação, moradia, medicamentos, transporte e internet; aumento da ansiedade e preocupações relacionadas à saúde e à situação financeira; redução ou ausência de renda; dificuldade para obter tratamento ou acesso aos serviços de saúde; aumento das despesas e telemedicina como alternativa menos onerosa. Conclusões: a pandemia acentuou a toxicidade financeira; portanto, as equipes de saúde precisam reconhecê-la como um evento adverso do tratamento oncológico e compreender que ela pode afetar diferentes âmbitos da vida dos pacientes.

Validação de Conteúdo e Aplicabilidade de Protocolo de Cuidados de Enfermagem a Vítimas de Queimaduras / Validación de Contenido y Aplicabilidad de Un Protocolo de Atención de Enfermería a Víctimas de Quemaduras / Content Validation and Applicability of a Nursing Care Protocol for Burn Victims

Objetivos:Construir e validar um protocolo de cuidados de enfermagem a pacientes adultos que sofreram queimaduras em um hospital público na Região Norte do Brasil e avaliar sua aplicabilidade. Método: Estudo metodológico que seguiu as etapas: construção do instrumento; validação do conteúdo utilizando a ferramenta de avaliação Appraisal of Guidelines for Research & Evaluation II (AGREE II); e análise de aplicabilidade com questionário semiestruturado com a equipe de enfermagem e por concordância e teste de Kappa. Resultados: Na etapa diagnóstico situacional, o protocolo foi elaborado com base na revisão de literatura e validado pelos especialistas por meio do instrumento AGREE II, com valor de índice de validade de conteúdo geral de 0,93, e da análise de aplicabilidade com análise de teste de Kappa, obtendo o valor de 0,81, com a concordância quase perfeita. Conclusão: O protocolo foi estruturado com qualidade para guiar a equipe de enfermagem na assistência ao paciente queimado, e indica-se, portanto, a sua utilização.

Objective:To build and validate a nursing care protocol to adult patients who suffered burns in a public hospital in the North region of Brazil and evaluate its applicability. Method: Methodological study that followed the steps: construction of the instrument; content validation using the Appraisal of Guidelines for Research & Evaluation II (AGREE II) assessment tool; and applicability analysis with a semi-structured questionnaire with the nursing team and by agreement and Kappa test. Results: In the situational diagnosis stage, the protocol was elaborated based on the literature review and validated by the specialists through the AGREE II instrument with a general content validity index value of 0.93 and through the analysis of applicability with Kappa test analysis, obtaining a value of 0.81, with almost perfect agreement. Conclusion: The protocol was structured with quality to guide the nursing team in assisting burned patients. Therefore, its use is indicated

Objetivo:Construir, validar y evaluar la aplicabilidad de un protocolo de atención de enfermería a pacientes adultos que sufrieron quemaduras en un hospital público de la región Norte de Brasil. Método: Estudio metodológico que siguió los siguientes pasos: construcción del instrumento; validación de contenido utilizando la herramienta de evaluación AGREE II; y análisis de aplicabilidad con cuestionario semiestructurado con el equipo de enfermería y de acuerdo y test KAPPA. Resultados: Desde la etapa de diagnóstico situacional, el protocolo fue elaborado con base en la revisión bibliográfica y validado por los especialistas a través del instrumento AGREE II con un valor de Índice de Validez de Contenido General (IVC) de 0,93 y mediante el análisis de aplicabilidad con el análisis del Test Kappa, obteniendo un valor de 0.81, con concordancia casi perfecta. Conclusión: El protocolo fue estructurado con calidad para orientar al equipo de enfermería en el cuidado del paciente quemado y, por tanto, está indicado su uso.

Calidad de vida y toxicidad financiera de los receptores de trasplantes de células madre hematopoyéticas en COVID-19 / Quality of life and financial toxicity of hematopoietic stem cell transplant recipients in COVID-19 / Qualidade de vida e toxicidade financeira dos transplantados de células-tronco hematopoéticas na COVID-19

Objetivo: evaluar y correlacionar la calidad de vida y la toxicidad financiera de pacientes adultos sometidos a trasplante de células madre hematopoyéticas durante el período de la pandemia de COVID-19. Método: estudio observacional, analítico, realizado con 35 pacientes en un hospital de referencia para trasplante en Latinoamérica. Para la recolección de datos, se utilizaron los cuestionarios Functional Assessment Cancer Therapy Bone Marrow Transplantation y el COmprehensive Score for financial Toxicity. Para el análisis de los datos se utilizaron las pruebas de correlación de Spearman y Mann-Whitney. Resultados: la calidad de vida general durante la COVID-19 mostró un puntaje bajo (67,09/108) con mayor deterioro en el bienestar funcional (14,47/28), bienestar social (16,76/28) y preocupaciones adicionales (23,41/40). Los promedios del grupo alogénico fueron inferiores a los del grupo autólogo en todos los dominios, presentando diferencia significativa en relación a preocupaciones adicionales (p=0,01) y en el índice de evaluación del tratamiento (p=0,04). Se consideró que la toxicidad financiera tenía un impacto leve (22.11/44). Se observó una relación, aunque no significativa, entre la calidad de vida y la toxicidad financiera (p=0,051). Conclusión: la calidad de vida de la muestra fue baja; existe una correlación entre la calidad de vida y la toxicidad financiera, aunque no significativa. Cuanto mayor es la toxicidad financiera, menor es la calidad de vida.

Objective: to evaluate and correlate the quality of life and financial toxicity of adult patients undergoing hematopoietic stem cell transplantation during the COVID-19 pandemic. Method: observational, analytical study, carried out with 35 patients in a reference hospital for transplantation in Latin America. For data collection, the Functional Assessment Cancer Therapy Bone Marrow Transplantation and COmprehensive Score for Financial Toxicity questionnaires were used. Spearman and Mann-Whitney correlation tests were used for data analysis. Results: general quality of life during COVID-19 had a low score (67.09/108) with greater impairment in functional well-being (14.47/28), social well-being (16.76/28) and additional concerns (23.41/40). The means of the allogeneic group were lower than those of the autologous group in all domains, showing a significant difference in relation to additional concerns (p=0.01) and in the treatment evaluation index (p=0.04). Financial toxicity was considered to have a slight impact (22.11/44). There was a relationship, albeit not significant, between quality of life and financial toxicity (p=0.051). Conclusion: the quality of life of the sample was low; there is a correlation between quality of life and financial toxicity, although not significant. The higher the financial toxicity, the lower the quality of life.

Objetivo: avaliar e correlacionar a qualidade de vida e a toxicidade financeira dos pacientes adultos submetidos ao transplante de células-tronco hematopoéticas no período da pandemia de COVID-19. Método: estudo observacional, analítico, realizado com 35 pacientes em um hospital de referência para o transplante na América Latina. Para coleta de dados, utilizaram-se os questionários Functional Assessment Cancer Therapy Bone Marrow Transplantation e COmprehensive Score for financial Toxicity. Na análise dos dados empregaram-se os testes de correlação de Spearman e Mann-Whitney. Resultados: a qualidade de vida geral, durante a COVID-19, apresentou baixo escore (67,09/108), com maior comprometimento nas funções bem-estar funcional (14,47/28), social (16,76/28) e preocupações adicionais (23,41/40). As médias do grupo alogênico foram inferiores às do autólogo em todos os domínios, apresentando diferença significativa em relação às preocupações adicionais (p=0,01) e ao índice de avaliação do tratamento (p=0,04). A toxicidade financeira foi considerada de impacto leve (22,11/44). Observou-se relação, ainda que não significativa, entre a qualidade de vida e a toxicidade financeira (p=0,051). Conclusão: a qualidade de vida da amostra foi baixa, logo há uma correlação entre qualidade de vida e a toxicidade financeira, embora não significativa. Quanto maior a toxicidade financeira, menor a qualidade de vida.

Quality of life and financial toxicity of hematopoietic stem cell transplant recipients in COVID-19. / Calidad de vida y toxicidad financiera de los receptores de trasplantes de células madre hematopoyéticas en COVID-19.

OBJECTIVE: to evaluate and correlate the quality of life and financial toxicity of adult patients undergoing hematopoietic stem cell transplantation during the COVID-19 pandemic. METHOD: observational, analytical study, carried out with 35 patients in a reference hospital for transplantation in Latin America. For data collection, the Functional Assessment Cancer Therapy Bone Marrow Transplantation and COmprehensive Score for Financial Toxicity questionnaires were used. Spearman and Mann-Whitney correlation tests were used for data analysis. RESULTS: general quality of life during COVID-19 had a low score (67.09/108) with greater impairment in functional well-being (14.47/28), social well-being (16.76/28) and additional concerns (23.41/40). The means of the allogeneic group were lower than those of the autologous group in all domains, showing a significant difference in relation to additional concerns (p=0.01) and in the treatment evaluation index (p=0.04). Financial toxicity was considered to have a slight impact (22.11/44). There was a relationship, albeit not significant, between quality of life and financial toxicity (p=0.051). CONCLUSION: the quality of life of the sample was low; there is a correlation between quality of life and financial toxicity, although not significant. The higher the financial toxicity, the lower the quality of life.

Financial toxicity in people with chronic kidney disease undergoing hemodialysis treatment.

OBJECTIVE: to assess the financial toxicity of people with chronic kidney disease undergoing hemodialysis treatment. METHOD: a descriptive analytical cross-sectional study, carried out with 214 people, between February and May 2022. For data collection, a sociodemographic and clinical instrument and the COmprehensive Score for financial Toxicity were used. For analysis, the Odds Ratio, ANOVA and Cronbach's alpha tests were used. RESULTS: the mean financial toxicity score was 20.30. Women with a monthly family income of at most two minimum wages are more likely to have some degree of financial toxicity (Odds Ratio: 0.85; 0.76). CONCLUSION: financial toxicity was identified to different degrees and varied according to sociodemographic and clinical characteristics. Measuring financial toxicity can help nurses plan care and develop strategies to avoid interrupting treatment.

Nursing care directed to burned patients: a scoping review.

OBJECTIVES: to identify in the literature and summarize nursing care in a hospital environment directed to patients who suffered burns. METHODS: a scoping review, according to the JBI Reviewers' Manual recommendations, with a search in the MEDLINE, CINAHL, Web of Science, Scopus databases and in the Virtual Health Library portal, through articles published between 2016 and December 2021. RESULTS: of the total 419 articles found, nine were selected for analysis. The main care measures identified were changing dressings and types of coverage, vital sign control, non-pharmacological techniques for pain relief and opioid reduction. CONCLUSIONS: the complexity of burn care requires constant updating by the nursing team. Keeping it prepared to carry out the best nursing care practices for burn patients will promote adequate care, patient recovery and reduction of possible harm.

Nursing care directed to burned patients: a scoping review / Cuidados de enfermería dirigidos a pacientes quemados: una revisión de alcance / Cuidados de enfermagem direcionados ao paciente queimado: uma revisão de escopo

ABSTRACT Objectives: to identify in the literature and summarize nursing care in a hospital environment directed to patients who suffered burns. Methods: a scoping review, according to the JBI Reviewers' Manual recommendations, with a search in the MEDLINE, CINAHL, Web of Science, Scopus databases and in the Virtual Health Library portal, through articles published between 2016 and December 2021. Results: of the total 419 articles found, nine were selected for analysis. The main care measures identified were changing dressings and types of coverage, vital sign control, non-pharmacological techniques for pain relief and opioid reduction. Conclusions: the complexity of burn care requires constant updating by the nursing team. Keeping it prepared to carry out the best nursing care practices for burn patients will promote adequate care, patient recovery and reduction of possible harm.

RESUMEN Objetivos: identificar en la literatura y resumir los cuidados de enfermería en ambiente hospitalario dirigidos a pacientes que sufrieron quemaduras. Métodos: revisión de alcance, según las recomendaciones del JBI Reviewers' Manual, con búsqueda en MEDLINE, CINAHL, Web of Science, Scopus y en el portal Biblioteca Virtual en Salud, a través de artículos publicados entre 2016 y diciembre de 2021. Resultados: del total de 419 artículos encontrados, nueve fueron seleccionados para el análisis. Las principales medidas de atención identificadas fueron cambio de apósitos y tipos de cobertura, control de signos vitales, técnicas no farmacológicas para el alivio del dolor y reducción de opioides. Conclusiones: la complejidad del cuidado de quemados exige una constante actualización por parte del equipo de enfermería. Mantenerlo preparado para llevar a cabo las mejores prácticas de atención de enfermería a los pacientes quemados promoverá la atención adecuada, la recuperación del paciente y la reducción de posibles daños.

RESUMO Objetivos: identificar na literatura e sintetizar os cuidados de enfermagem em ambiente hospitalar direcionados aos pacientes que sofreram queimaduras. Métodos: revisão de escopo, segundo recomendações do JBI Reviewers' Manual, com busca nas bases MEDLINE, CINAHL, Web of Science, Scopus e no portal Biblioteca Virtual em Saúde, através de artigos publicados entre 2016 e dezembro 2021. Resultados: do total 419 artigos encontrados, nove foram selecionados para análise. Os principais cuidados identificados foram troca de curativos e tipos de coberturas, controle dos sinais vitais, técnicas não farmacológicas para atenuação da dor e redução de opioides. Conclusões: a complexidade do cuidado em queimaduras requer constantes atualizações da equipe de enfermagem. Mantê-la preparada para a realização das melhores práticas de cuidado de enfermagem aos pacientes queimados promoverá a assistência adequada, recuperação do paciente e redução de possíveis danos.

Financial toxicity in people with chronic kidney disease undergoing hemodialysis treatment / Toxicidad financiera en personas con enfermedad renal crónica en tratamiento de hemodiálisis / A toxicidade financeira em pessoas com doença renal crônica em tratamento hemodialítico

ABSTRACT Objective: to assess the financial toxicity of people with chronic kidney disease undergoing hemodialysis treatment. Method: a descriptive analytical cross-sectional study, carried out with 214 people, between February and May 2022. For data collection, a sociodemographic and clinical instrument and the COmprehensive Score for financial Toxicity were used. For analysis, the Odds Ratio, ANOVA and Cronbach's alpha tests were used. Results: the mean financial toxicity score was 20.30. Women with a monthly family income of at most two minimum wages are more likely to have some degree of financial toxicity (Odds Ratio: 0.85; 0.76). Conclusion: financial toxicity was identified to different degrees and varied according to sociodemographic and clinical characteristics. Measuring financial toxicity can help nurses plan care and develop strategies to avoid interrupting treatment.

RESUMEN Objetivo: evaluar la toxicidad financiera de personas con enfermedad renal crónica en tratamiento de hemodiálisis. Método: estudio transversal analítico descriptivo, realizado con 214 personas, entre febrero y mayo de 2022. Para la recolección de datos se utilizó un instrumento sociodemográfico, clínico y el COmprehensive Score for financial Toxicity. Para el análisis se utilizaron las pruebas de Odds Ratio, ANOVA y alfa de Cronbach. Resultados: la puntuación media de toxicidad financiera fue de 20,30. Las mujeres con un ingreso familiar mensual de a lo sumo dos salarios mínimos tienen más probabilidades de tener algún grado de toxicidad financiera (Odds Ratio: 0,85; 0,76). Conclusión: la toxicidad financiera se identificó en diferentes grados y varió según las características sociodemográficas y clínicas. Medir la toxicidad financiera puede ayudar a las enfermeras a planificar la atención y desarrollar estrategias para evitar la interrupción del tratamiento.

RESUMO Objetivo: avaliar a toxicidade financeira de pessoas com doença renal crônica em tratamento hemodialítico. Método: estudo descritivo analítico com corte transversal, realizado com 214 pessoas, entre os meses de fevereiro e maio de 2022. Para coleta de dados, utilizou-se instrumento sociodemográfico e clínico e o COmprehensive Score for financial Toxicity. Para análise, utilizaram-se os testes Odds Ratio, ANOVA e alfa de Cronbach. Resultados: a média do escore da toxicidade financeira foi de 20,30. Pessoas do sexo feminino e com renda familiar mensal de no máximo dois salários mínimos têm maiores chances de apresentar algum grau de toxicidade financeira (Odds Ratio: 0,85; 0,76). Conclusão: a toxicidade financeira foi identificada em diferentes graus e variou de acordo com as características sociodemográficas e clínicas. A mensuração da toxicidade financeira pode auxiliar o enfermeiro no planejamento do cuidado e na elaboração de estratégias para evitar a interrupção do tratamento.

Qualidade de Vida Relacionada à Saúde e Satisfação com o Tratamento Hospitalar de Adultos com Câncer: Estudo Observacional / Health-Related Quality of Life and Satisfaction with Hospital Treatment in Adults with Cancer: Observational Study / Calidad de Vida Relacionada con la Salud y Satisfacción con el Tratamiento Hospitalario en Adultos con Cáncer: Estudio Observacional

Introdução: Pacientes com câncer enfrentam percurso terapêutico longo e de alto nível de complexidade. Diante desse cenário, a satisfação com o tratamento hospitalar é um processo importante na recuperação da saúde, dada a possibilidade de se obter informações essenciais referentes às experiências de quem recebe o tratamento, as quais auxiliarão na adequação de condutas para prática da assistência de qualidade com possíveis implicações na qualidade de vida relacionada à saúde (QVRS). Objetivo: Analisar a QVRS e sua relação com a satisfação com o tratamento hospitalar de adultos com câncer. Método: Estudo observacional, analítico, de recorte transversal, realizado com 120 pacientes em tratamento clínico ou cirúrgico em um hospital referência no tratamento onco-hematológico localizado no Sul do Brasil, entre agosto de 2021 e janeiro de 2022. Foram utilizados os instrumentos Quality of Life Questionnaire Core 30 e Satisfaction with In-Patient Cancer Care, analisados descritivamente e por teste de correlação de Spearman. Resultados: A qualidade de vida global apresentou baixos escores (58,54/100) e maior comprometimento no domínio função social (44,17/100). Houve alto nível de satisfação com a equipe médica e de enfermagem, e maiores médias na escala habilidades técnicas (89,44/100 e 86,67/100, respectivamente). Verificou-se significância estatística entre a qualidade de vida global e todos os itens do instrumento de satisfação (p<0,05). Conclusão: A satisfação com o tratamento hospitalar impacta na qualidade de vida de adultos com câncer. Reconhecer as alterações na qualidade de vida e os determinantes que compõem a satisfação ao tratamento hospitalar pode contribuir para o aperfeiçoamento da assistência prestada.

Introduction: Patients with cancer face a long and high level of complexity therapeutic path. Given this scenario, satisfaction with hospital treatment is an important process in the recovery of health, because of the possibility of obtaining essential information about the experiences of those receiving treatment, which will help to match the conduct for the practice of quality care with possible implications for health-related quality of life (HRQL). Objective: To analyze the HRQL and its relationship with satisfaction with hospital treatment of adults with cancer. Method: Observational, analytical cross-sectional study conducted with 120 patients undergoing clinical or surgical treatment at a reference hospital of oncohematological treatment located in Southern Brazil between August 2021 and January 2022. The instruments used were Quality of Life Questionnaire Core 30 and Satisfaction with In-Patient Cancer Care, analyzed descriptively and by Spearman correlation test. Results: Global quality of life had low scores (58.54/100), greater impairment of the social functioning domain (44.17/100). There was a high level of satisfaction with medical and nursing staff, higher averages of the technical skills scale (89.44/100 and 86.67/100, respectively). Statistical significance was found between global quality of life and all items of the satisfaction instrument (p<0.05). Conclusion: Satisfaction with hospital treatment impacts the quality of life of adults with cancer. Recognizing changes in quality of life and determinants of the satisfaction with hospital treatment can contribute to improve the care provided.

Introducción: Los pacientes con cáncer enfrentan una larga y compleja experiencia terapéutica. Ante ese escenario, la satisfacción con el tratamiento hospitalario es un proceso importante en la recuperación de la salud, dada la posibilidad de obtener informaciones esenciales referentes a las experiencias de quien recibe el tratamiento, las cuales ayudarán en la adecuación de conductas para la práctica de la asistencia de calidad con posibles implicaciones en la calidad de vida relacionada con la salud (CVRS). Objetivo: Analizar la CVRS y su relación con la satisfacción con el tratamiento hospitalario de adultos con cáncer. Método: Estudio observacional, analítico, de corte transversal, realizado con 120 pacientes en tratamiento clínico o quirúrgico en un hospital referencia en el tratamiento oncohematológico localizado en el Sur de Brasil, entre agosto de 2021 y enero de 2022. Se utilizaron los instrumentos Quality of Life Questionnaire Core 30 y Satisfaction with In-Patient Cancer Care, analizados descriptivamente y por prueba de correlación de Spearman. Resultados: La calidad de vida global presentó bajas puntuaciones (58,54/100), mayor comprometimiento en el dominio función social (44,17/100). Hubo un alto nivel de satisfacción con el personal médico y de enfermería, mayores promedios en la escala habilidades técnicas (89,44/100 y 86,67/100, respectivamente). Se verificó significación estadística entre la calidad de vida global y todos los ítems del instrumento de satisfacción (p<0,05). Conclusión: La satisfacción con el tratamiento hospitalario impacta en la calidad de vida de adultos con cáncer. Reconocer los cambios en la calidad de vida y determinantes que componen la satisfacción al tratamiento hospitalario puede contribuir a mejorar la asistencia prestada.

Detecção precoce de câncer em trabalhadores rurais: revisão de escopo / Early detection of cancer in rural workers: ascoping review

Objetivo: sintetizar o conhecimento existente na literatura sobre as medidas de detecção precoce do câncer voltadas aos trabalhadores rurais. Métodos: trata-se de uma scoping review realizada em abril de 2021, nas plataformas de busca de dados National Library of Medicine, Cumulative Index to Nursing and Allied Health Literature, Scopuse Biblioteca Virtual em Saúde. Incluíram-se artigos na íntegra em inglês, português ou espanhol, com enfoque na detecção precoce dos cânceres relacionados aos trabalhadores rurais, estudos controlados randomizados e não randomizados, de caso, coorte, pesquisa qualitativa ou descritiva, e caso-controle. Resultados: a revisão incluiu 21 estudos publicados entre 2012 e 2019. Da análise, foram identificadas barreiras que esses trabalhadores enfrentam no acesso aos programas de detecção: recursos limitados nas instituições de saúde, localização da residência, pouco conhecimento relacionado ao câncer e questões financeiras. As principais medidas de detecção precoce indicadas para o meio rural são: uso de testes rápidos, como teste de sangue oculto nas fezes, autoexame, inspeção visual do profissional, teledermatologia, treinamento de membros da comunidade e uso de clínicas móveis. Conclusão: o presente estudo possibilita que profissionais de saúde, principalmente enfermeiros, atualizem seus conhecimentos sobre a detecção precoce do câncer, visando ao cuidado mais assertivo no meio rural. Descritores: Detecção precoce de câncer. Trabalhadores rurais. Enfermagem oncológica. Diagnóstico precoce. Programas de rastreamento.

Objective: to synthesize the current knowledge in the literature on measures for early detection of cancer aimed at rural workers. Methods: this is a scoping review carried out in April 2021 on the National Library of Medicine, Cumulative Index to Nursing and Allied Health Literature, Scopus and Biblioteca Virtual em Saúdedata search platforms. Full-text articles in English, Portuguese or Spanish were included, focusing on early detection of the types of cancer related to rural workers, as well as randomized and non-randomized controlled studies, case, cohort, qualitative or descriptive research, and case-control studies. Results: the review included 21 studies published between 2012 and 2019. From the analysis, barriers faced by these workers in accessing the detection programs were identified, namely: limited resources in health institutions, place of residence, limited knowledge in relation to cancer, and financial issues. The main early detection measures indicated for rural areas are as follows: use of rapidtests, such as fecal occult blood test, self-examination, visual inspection by a professional, Teledermatology, training of community members, and use of mobile clinics. Conclusion: the current study enables health professionals,especially nurses, to updatetheir knowledge about early detection of cancer, aiming at more assertive care in rural areas. Descriptors: Early Detection of Cancer. Farmers. Oncology Nursing. Early Diagnosis. Mass Screening.

Avaliação da toxicidade financeira (facitcost) de pacientes com câncer no sul do brasil / Assessment of financial toxicity (facit-cost) of patients with cancer in southern brazil / Evaluación de la toxicidad financiera (facitcost) de los pacientes con cáncer en el sur de brasil

RESUMO Objetivo: avaliar a toxicidade financeira e correlacionar o escore total com as características sociodemográficas e clínicas de pacientes com câncer assistidos em instituições pública e privada. Método: estudo transversal descritivo, realizado entre setembro de 2018 a janeiro de 2020 com 126 pacientes em tratamento quimioterápico no estado do Paraná, Brasil. Utilizou-se instrumento sociodemográfico e clínico e COmprehensive Score for financial Toxicity; para análise, o teste t de Student e Scoring Guidelines. Resultados: o escore médio da toxicidade financeira na amostra da instituição pública foi de 16,33, na privada de 24,02. Unindo as amostras, o escore médio foi de 18,95. Ao realizar correlação, verificou-se significância estatística com a renda na instituição pública (p-valor=0,002); na instituição privada, presença de comorbidade (p-valor=0,003) e uso de medicamentos (p-valor=0,042). Conclusão: reconhecer a toxicidade financeira como evento adverso auxiliará os profissionais num plano assistencial de acordo com as condições do paciente.

ABSTRACT Objective: to assess financial toxicity and associate the total score with the sociodemographic and clinical profile of cancer patients assisted in public and private institutions. Method: descriptive cross-sectional research conducted from September 2018 to January 2020 with 126 patients undergoing chemotherapy in the state of Paraná, Brazil. A sociodemographic and clinical instrument and the COmprehensive Score for financial Toxicity were used; Student's t-test and Scoring Guidelines were used for analysis. Results: the mean score of financial toxicity in the public institution sample was 16.33, in the private one 24.02. Combining the samples, the average score was 18.95. In the correlation analysis, statistical significance was found with the income in the public institution (p-value=0.002); in the private institution, having comorbidity (p-value=0.003) and use of medication (p-value=0.042). Conclusion: recognizing financial toxicity as an adverse event will help professionals to develop a care plan according to the patient's conditions.

RESUMEN Objetivo: evaluar la toxicidad financiera y correlacionar la puntuación total con las características sociodemográficas y clínicas de los pacientes con cáncer asistidos en instituciones públicas y privadas. Método: estudio descriptivo transversal realizado entre septiembre de 2018 y enero de 2020 con 126 pacientes en tratamiento de quimioterapia en el estado de Paraná, Brasil. Se utilizó el instrumento sociodemográfico y clínico y el COmprehensive Score for financial Toxicity; para el análisis, la prueba t de Student y las Scoring Guidelines. Resultados: la puntuación media de toxicidad financiera en la muestra de instituciones públicas fue de 16,33 y de 24,02 en la privada. Uniendo las muestras, la puntuación media fue de 18,95. Al realizar la correlación, se verificó la significación estadística con el ingreso en la institución pública (p-valor=0,002); en la institución privada, la presencia de comorbilidad (p-valor=0,003) y el uso de medicamentos (p-valor=0,042). Conclusión: reconocer la toxicidad financiera como un evento adverso ayudará a los profesionales en un plan de asistencia de acuerdo con las condiciones del paciente.

Qualidade de vida de pacientes com metástase hepática em decorrência de câncer colorretal / Calidad de vida de los pacientes con metástasis hepática por cáncer colorrectal / Quality of life of patients with liver metastasis due to colorectal cancer

Objetivo: avaliar e correlacionar os domínios da qualidade de vida de pacientes com metástase hepática de câncer colorretal em tratamento quimioterápico. Método: estudo transversal, observacional, com 106 pacientes selecionados em três hospitais do Sul do Brasil. Os dados foram coletados com o Quality of Life Questionnaire Core 30 e Quality of Life Questionnaire Colorectal Liver Metastases, analisados descritivamente e pelo teste de correlação de Spearman. Resultados: a vida sexual (45,08%), função emocional (43,08%) e fadiga (40,15%) tiveram os piores escores com o Quality of Life Questionnaire Colorectal Liver Metastases. Todas as correlações entre os domínios são significativas, demonstrando que um domínio com escore baixo interfere em todos os demais. Conclusão: os pacientes com metástase hepática de câncer colorretal em tratamento quimioterápico apresentaram alteração nos domínios de qualidade de vida.

Objetivo: evaluar y correlacionar los dominios de calidad de vida de pacientes con metástasis hepática de cáncer colorrectal sometidos a quimioterapia. Método: estudio observacional transversal con 106 pacientes seleccionados en tres hospitales del sur de Brasil. Los datos fueron recolectados mediante el Quality of Life Questionnaire Core 30 y Quality of Life Questionnaire Colorectal Liver Metastases, analizados descriptivamente y mediante la prueba de correlación de Spearman. Resultados: la vida sexual (45,08%), la función emocional (43,08%) y la fatiga (40,15%) tuvieron las peores puntuaciones con el Quality of Life Questionnaire Colorectal Liver Metastases. Todas las correlaciones entre los dominios son significativas, demostrando que un dominio con una puntuación baja interfiere en todos los demás. Conclusión: los pacientes con metástasis hepática por cáncer colorrectal sometidos a quimioterapia mostraron cambios en los dominios de calidad de vida.

Objective: to evaluate and correlate the quality of life domains of patients with liver metastasis of colorectal cancer undergoing chemotherapy. Method: cross-sectional, observational study with 106 patients selected in three hospitals in southern Brazil. Data were collected using the Quality of Life Questionnaire Core 30 and Quality of Life Questionnaire Colorectal Liver Metastases, analyzed descriptively and by Spearman's correlation test. Results: sexual life (45.08%), emotional function (43.08%) and fatigue (40.15%) had the worst scores with the Quality of Life Questionnaire Colorectal Liver Metastases. All correlations between the domains are significant, demonstrating that a domain with a low score interferes in all others. Conclusion: patients with liver metastasis from colorectal cancer undergoing chemotherapy showed changes in quality of life domains.

Quality of life and changes in the social dimension of hematopoietic stem cell transplants recipients.

OBJECTIVES: to assess/correlate health-related quality of life with the social dimension of hematopoietic, autologous and allogeneic stem cell transplant patients in the three years post-transplant. METHODS: longitudinal, observational study with 55 patients, in a reference hospital in Latin America, from September 2013 to February 2019, using the Quality of Life Questionnaire-Core and Functional Assessment Cancer Therapy Bone Marrow Transplantation. RESULTS: A total of 71% underwent allogeneic transplantation. The social dimension had low averages since the baseline stage (55, 21) and low scores (56) for quality of life in pancytopenia. There was a significant positive correlation between social dimension, quality of life in pancytopenia (p<0.01) and follow-up after hospital discharge (p<0.00). There is a significant difference (p<0.00) throughout the stages, however, not in terms of the type of transplant (p>0.36/0.86). CONCLUSIONS: patients with better assessments in the social dimension have a better quality of life. Interventions focusing on the multidimensionality of the quality of life construct are necessary.

Implications of financial toxicity in the lives of cancer patients: a reflection.

OBJECTIVE: To reflect on the understanding of financial toxicity, as an adverse event of cancer diagnosis and treatment, and its implications on the quality of life of these patients. METHOD: Reflexive study, based on the international literature about the concept of financial toxicity and its relationship with quality of life. RESULTS: Financial toxicity is related to the financial difficulties associated with cancer and its treatment, which occur in the lives of patients and family members. Its consequences include: possible worsening of the clinical symptoms, indebtedness, loss of professional opportunities, changes in family habits and decline in quality of life. FINAL CONSIDERATIONS: Measures to minimize financial toxicity should also be a concern of the state and be part of the therapeutic itinerary of cancer patients. Dialogue can become an essential tool for the health team to clarify the therapeutic options and their costs. This attitude shows respect and preserves the patient's autonomy, which can minimize the feeling of helplessness in the face of the disease.

Tradução, adaptação transcultural e validação do questionário Comprehensive Score for Financial Toxicity (COST) para a cultura brasileira / Translation, cross-cultural adaptation and validation of the Comprehensive Score for Financial Toxicity (COST) questionnaire for Brazilian culture

Este estudo está inserido na linha de pesquisa o Processo de Cuidar em Saúde e Enfermagem, e integra o Grupo de Pesquisa Multiprofissional em Saúde do Adulto da Universidade Federal do Paraná. Introdução: a toxicidade financeira é um efeito colateral do tratamento oncológico, que descreve o ônus financeiro experimentado pelo paciente com câncer, o qual tem dificuldade para custear o tratamento e os custos decorrentes da doença. O questionário COmprehensive Score for Financial Toxicity foi desenvolvido e validado para mensurar a toxicidade financeira dos pacientes com câncer. Objetivo: traduzir, adaptar transculturalmente e validar o questionário COmprehensive Score for Financial Toxicity para a cultura brasileira. Método: pesquisa metodológica dividida em duas etapas: a primeira, denominada tradução e adaptação transcultural, utilizou o referencial metodológico do grupo Functional Assessment of Chronic Illness Therapy, e a segunda, validação das propriedades psicométricas, foi realizada de acordo com o referencial de Pasquali. A primeira etapa foi concluída em julho de 2018, e a segunda foi realizada entre setembro de 2018 e janeiro de 2020. Participaram da primeira etapa, quatro tradutores, dois profissionais de saúde e 15 pacientes com diagnóstico de câncer no pré-teste, e da segunda etapa, 126 pacientes com câncer. Quarenta e três (43) pacientes realizaram tratamento em instituição privada e 83 em instituição pública no sul do Brasil. Para a etapa de validação, foi realizada o coeficiente Alfa de Cronbach para verificação da consistência interna, a análise fatorial exploratória, análise fatorial confirmatória. Resultados: a participação dos tradutores, desenvolvedores e especialistas conferiu a validade de conteúdo do questionário. O coeficiente alfa de Cronbach, encontrado no pré-teste, foi de 0,83. As Análises fatorial exploratória e confirmatória revelaram que o questionário COmprehensive Score for Financial Toxicity, versão brasileira, mede um único construto, ou seja, a toxicidade financeira com valor de - ??2/????= 179,78, CFI=0,00, PGFI= 0,302, RMSEA=1,196 e Pclose=0,000. O alfa de Cronbach da segunda etapa foi de 0,815. Ao realizar a comparação do escore entre as amostras, foi possível constatar que a amostra da instituição privada possui escore 24,02 e a amostra da instituição pública, escore 16,33, indicando que aqueles que possuem plano privado de saúde, tem menor toxicidade financeira (p=0,001). Conclusão: o questionário COmprehensive Score for Financial Toxicity é válido e confiável para mensurar a toxicidade financeira dos pacientes com câncer no Brasil.

This study is included in the research line the Process of Caring for Health and Nursing and is part of the Multiprofessional Research Group on Adult Health at the Federal University of Paraná. Introduction: financial toxicity is a side effect of cancer treatment, which describes the financial burden experienced by cancer patients, who have trouble affording the treatment and the costs resulting from the disease. The COmprehensive Score for Financial Toxicity questionnaire was developed and validated to measure the financial toxicity of cancer patients. Objective: to translate, cross-culturally adapt and validate the COmprehensive Score for Financial Toxicity questionnaire for the Brazilian culture. Method: this is a methodological research divided into two stages: the first, named translation and cross-cultural adaptation, which used the methodological framework of the Functional Assessment of Chronic Illness Therapy group, and the second, psychometric properties validation, which was carried out according to Pasquali's framework. The first stage was accomplished in July 2018, and the second from September 2018 and January 2020. Four translators, two health professionals and 15 patients diagnosed with cancer in the pre-test participated in the first stage, and 126 cancer patients in the second stage. Forty-three (43) patients underwent treatment in a private institution and 83 in a public institution in southern Brazil. For the validation stage, Cronbach's alpha coefficient was calculated to check internal consistency and exploratory factorial analysis, confirmatory factorial analysis was performed. Results: the participation of translators, developers and specialists checked the questionnaire content validity. Cronbach's alpha coefficient, found in the pre-test, was 0.83. The exploratory and confirmatory factorial analyzes showed that the questionnaire COmprehensive Score for Financial Toxicity, Brazilian version, measures a single construct, that is, the financial toxicity with a value of - ??2/???? = 179.78, CFI=0.00, PGFI = 0.302, RMSEA = 1.196 and Pclose=0.000. Cronbach's alpha for the second stage was 0.815. When comparing the score between the samples, it was possible to verify that the private institution sample has a score of 24.02 and the sample of the public institution, a score of 16.33, indicating that those who have a private health plan have less financial toxicity (p=0.001). Conclusion: the COmprehensive Score for Financial Toxicity questionnaire is valid and reliable for measuring the financial toxicity of cancer patients in Brazil.