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2.
Lancet Infect Dis ; 24(2): e106-e112, 2024 Feb.
Article in English | MEDLINE | ID: mdl-37778362

ABSTRACT

Next-generation sequencing (NGS) of genomic data has established its fundamental value in public health surveillance, research and development, and precision medicine. In Africa, severe shortages of competent experts in genomics and bioinformatics, few opportunities for research, and inadequate genomic infrastructure have had a knock-on effect on the use of NGS technologies for research and public health practice. Several reasons-ranging from poor funding, inadequate infrastructure for training and practice, to brain drain-might partly account for the scarcity of genomics and bioinformatics expertise in the region. In recognition of these shortcomings and the importance of NGS genomic data, which was amplified during the COVID-19 pandemic in mid-2021, the Africa Centres for Disease Control and Prevention (Africa CDC) through the Africa Pathogen Genomics Initiative began building and expanding Africa's workforce in pathogen surveillance. By the end of 2022, the Africa CDC in collaboration with its partners and centres of excellence had trained 413 personnel, mostly from public health institutions, in 53 (96%) of 55 African Union Member States. Although this training has increased genomics, bioinformatics, and genomic epidemiology literacy, and genomic-informed pathogen surveillance, there is still a need for a strategic and sustainable public health workforce development in Africa.


Subject(s)
Genomics , Pandemics , Humans , Africa/epidemiology , Computational Biology , Workforce
4.
PLoS Biol ; 20(8): e3001769, 2022 08.
Article in English | MEDLINE | ID: mdl-35998195

ABSTRACT

We propose a novel, non-discriminatory classification of monkeypox virus diversity. Together with the World Health Organization, we named three clades (I, IIa and IIb) in order of detection. Within IIb, the cause of the current global outbreak, we identified multiple lineages (A.1, A.2, A.1.1 and B.1) to support real-time genomic surveillance.


Subject(s)
Monkeypox virus , Mpox (monkeypox) , Disease Outbreaks , Genomics , Humans , Mpox (monkeypox)/diagnosis , Mpox (monkeypox)/epidemiology , Monkeypox virus/genetics
5.
Tob Control ; 22(6): 423-6, 2013 Nov.
Article in English | MEDLINE | ID: mdl-22628169

ABSTRACT

OBJECTIVE: To assess the level of public support for tobacco control policies and to discuss how these findings could be used to influence the legislative process in the passing of tobacco control law in the country. METHODS: A cross-sectional study conducted in Kenya between March and May 2007 on a random sample of 2021 (991 men and 1030 women) respondents aged 18 years and above. Interviews were done using a structured questionnaire by a research consultancy firm with long-standing experience in public polling. RESULTS: The majority of respondents supported tobacco control policies as proposed by WHO Framework Convention on Tobacco Control. For example, 95% of the respondents supported smoking restrictions in all enclosed public places and workplaces, 94% supported visible health warnings on tobacco product packages, 83% supported a ban on advertisements of cigarettes and tobacco products and 69% supported a ban on sponsorship of events by tobacco companies. However, 60% perceived that there was very little commitment by legislators to tobacco control. CONCLUSIONS: There was overwhelming public support for tobacco control policies and a general view that government was not doing enough in implementing policies to protect the public from tobacco harm. This public opinion poll was used as an advocacy tool to generate support among legislators for national tobacco control law.


Subject(s)
Attitude to Health , Health Policy/legislation & jurisprudence , Marketing/legislation & jurisprudence , Public Opinion , Smoking Cessation , Smoking/legislation & jurisprudence , Tobacco Industry/legislation & jurisprudence , Adolescent , Adult , Cross-Sectional Studies , Drug Labeling , Female , Government Regulation , Humans , Interviews as Topic , Kenya , Male , Middle Aged , Perception , Smoke-Free Policy , Surveys and Questionnaires , Tobacco Products , Tobacco Smoke Pollution/legislation & jurisprudence , Tobacco Use Disorder/prevention & control , Workplace , Young Adult
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