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1.
Annu Int Conf IEEE Eng Med Biol Soc ; 2017: 21-24, 2017 Jul.
Article in English | MEDLINE | ID: mdl-29059801

ABSTRACT

Recently, highly flexible and soft pressure distribution imaging sensor is in great demand for tactile sensing, gait analysis, ubiquitous life-care based on activity recognition, and therapeutics. In this study, we integrate the piezo-capacitive and piezo-electric nanowebs with the conductive fabric sheets for detecting static and dynamic pressure distributions on a large sensing area. Electrical impedance tomography (EIT) and electric source imaging are applied for reconstructing pressure distribution images from measured current-voltage data on the boundary of the hybrid fabric sensor. We evaluated the piezo-capacitive nanoweb sensor, piezo-electric nanoweb sensor, and hybrid fabric sensor. The results show the feasibility of static and dynamic pressure distribution imaging from the boundary measurements of the fabric sensors.


Subject(s)
Pressure , Electric Impedance , Electricity , Tomography
2.
Annu Int Conf IEEE Eng Med Biol Soc ; 2017: 349-351, 2017 Jul.
Article in English | MEDLINE | ID: mdl-29059882

ABSTRACT

Electrical impedance tomography (EIT) allows functional imaging of regional lung ventilation for real-time bedside monitoring of mechanically ventilated patients. Images showing time-changes of regional air distributions in the lungs can provide valuable diagnostic information for lung protective mechanical ventilation. This paper reports in vivo porcine imaging experiments of regional lung ventilation using a 16-channel parallel EIT system. Real-time time-difference chest images of 10 animals were reconstructed during mechanical ventilations with a temporal resolution of 50 frame/s. Analyzing the images together with the airway volume-pressure information from the mechanical ventilator, we could successfully produce regional compliance images at PEEP (positive end expiratory pressure) titration. From in vivo animal experiments, we propose the method as a continuous monitoring means for LPV (lung protective ventilation).


Subject(s)
Lung , Animals , Electric Impedance , Positive-Pressure Respiration , Swine , Tidal Volume , Tomography
3.
Physiol Meas ; 36(6): 1297-309, 2015 Jun.
Article in English | MEDLINE | ID: mdl-26006739

ABSTRACT

Recent studies showed that regional pulmonary perfusion can be reliably estimated using electrical impedance tomography (EIT) with the aid of hypertonic saline based contrast enhancement. Building on these successful studies, we studied contrast EIT for pulmonary perfusion defect caused by an artificially induced pulmonary embolism (PE) in a large ovine model (N = 8, 78 ± 7.8 kg). Furthermore, the efficacy of a less invasive contrast bolus of 0.77 ml kg(-1) of NaCl 3% was compared with a more concentrated bolus of 0.13 ml kg(-1) of NaCl 20%. Prior to the injection of each contrast bolus injection, ventilation was turned off to provide a total of 40 to 45 s of apnoea. Each bolus of impedance contrast was injected through a catheter into the right atrium. Pulmonary embolisation was performed by balloon occlusion of part of the right branch of the pulmonary trunk. Four parameters representing the kinetics of the contrast dilution in the lung were evaluated for statistical differences between baseline and PE, including peak value, maximum uptake, maximum washout and area under the curve of the averaged contrast dilution curve in each lung. Furthermore, the right lung to left lung (R2L) ratio of each the aforementioned parameters were assessed. While all of the R2L ratios yielded significantly different means between baseline and PE, it can be concluded that the R2L ratios of area under the curve and peak value of the averaged contrast dilution curve are the most promising and reliable in assessing PE. It was also found that the efficacy of the two types of impedance contrasts were not significantly different in distinguishing PE from baseline in our model.


Subject(s)
Pulmonary Embolism/diagnosis , Pulmonary Embolism/physiopathology , Regional Blood Flow , Tomography , Animals , Blood Volume , Electric Impedance , Male , Sheep
4.
Phys Rev Lett ; 109(18): 183902, 2012 Nov 02.
Article in English | MEDLINE | ID: mdl-23215280

ABSTRACT

We observe off-axis phase-matched terahertz generation in long air-plasma filaments produced by femtosecond two-color laser focusing. Here, phase matching naturally occurs due to off-axis constructive interference between locally generated terahertz waves, and this determines the far-field terahertz radiation profiles and yields. For a filament longer than the characteristic two-color dephasing length, it emits conical terahertz radiation in the off-axis direction, peaked at 4-7° depending on the radiation frequencies. The total terahertz yield continuously increases with the filament length, well beyond the dephasing length. The phase-matching condition observed here provides a simple method for scalable terahertz generation in elongated plasmas.

5.
Opt Express ; 20(18): 19778-86, 2012 Aug 27.
Article in English | MEDLINE | ID: mdl-23037030

ABSTRACT

Two-dimensional (2-D) transverse photocurrent generation is studied and applied to control and optimize terahertz energy and polarization in two-color, laser-produced air filaments. A full control of terahertz output is demonstrated and explained in the context of 2-D photocurrent model.


Subject(s)
Lasers , Lighting/instrumentation , Plasma Gases/chemistry , Computer-Aided Design , Equipment Design , Equipment Failure Analysis , Terahertz Radiation
6.
Comput Biol Med ; 42(11): 1122-32, 2012 Nov.
Article in English | MEDLINE | ID: mdl-23017828

ABSTRACT

The conductivity distribution around the thorax is altered during the cardiac cycle due to the blood perfusion, heart contraction and lung inflation. Previous studies showed that these bio-impedance changes are appropriate for non-invasive cardiac function imaging using Electrical Impedance Tomography (EIT) techniques. However, the spatial resolution is presently low. One of the main obstacles in cardiac imaging at the heart location is the large impedance variation of the lungs by respiration and muscles on the dorsal and posterior side of the body. In critical care units there is a potential to insert an internal electrode inside the esophagus directly behind the heart in the same plane of the external electrodes. The aim of the present study is to evaluate different current stimulation and measurement patterns with both external and internal electrodes. Analysis is performed with planar arrangement of 16 electrodes for a simulated 3D cylindrical tank and pig thorax model. In our study we evaluated current injection patterns consisting of adjacent, diagonal, trigonometric, and radial to the internal electrode. The performance of these arrangements was assessed using quantitative methods based on distinguishability, sensitivity and GREIT (Graz consensus Reconstruction algorithm for Electrical Impedance Tomography). Our evaluation shows that an internal electrode configuration based on the trigonometric injection patterns has better performance and improves pixel intensity of the small conductivity changes related to heart near 1.7 times in reconstructed images and also shows more stability with different levels of added noise. For the internal electrode, when we combined radial or adjacent injection with trigonometric injection pattern, we found an improvement in amplitude response. However, the combination of diagonal with trigonometric injection pattern deteriorated the shape deformation (correlation coefficient r=0.344) more than combination of radial and trigonometric injection (correlation coefficient r=0.836) for the perturbations in the area close to the center of the cylinder. We also find that trigonometric stimulation pattern performance is degraded in a realistic thorax model with anatomical asymmetry. For that reason we recommend using internal electrodes only for voltage measurements and as a reference electrode during trigonometric stimulation patterns in practical measurements.


Subject(s)
Electrodiagnosis/instrumentation , Electrodiagnosis/methods , Heart Function Tests/instrumentation , Heart Function Tests/methods , Tomography/instrumentation , Tomography/methods , Algorithms , Animals , Electric Conductivity , Electric Impedance , Electric Stimulation , Electrodes , Finite Element Analysis , Image Processing, Computer-Assisted/methods , Models, Theoretical , Signal Processing, Computer-Assisted , Swine , Thorax/anatomy & histology , Thorax/physiology
7.
Appl Opt ; 30(31): 4565-73, 1991 Nov 01.
Article in English | MEDLINE | ID: mdl-20717250

ABSTRACT

Infrared minus-filter coatings on zinc selenide substrates have been developed with a new design concept. This concept gives either a narrow or a wide rejection band by adjusting the varying shift factors. Most of the optimized designs are characterized by low-ripple optical performance in all high-transmittance regions.

8.
Appl Opt ; 27(20): 4255-9, 1988 Oct 15.
Article in English | MEDLINE | ID: mdl-20539553

ABSTRACT

A series of five broadband antireflection coatings on germanium substrates was deposited with or without ion-assisted deposition at a substrate temperature of 220 degrees C. Measurements of laser-damage threshold for 10.6- microm 0.1-micros pulses were made on these coatings. Germanium films deposited under simultaneous argon-ion bombardments show higher laser-damage threshold and substantially better durability of the AR coatings on the germanium substrates.

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