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1.
Pan Afr Med J ; 30: 6, 2018.
Article in English | MEDLINE | ID: mdl-30123409

ABSTRACT

Familial adenomatous polyposis syndrome is a rare condition characterized by the presence of numerous adenomatous polyps in the gastrointestinal tract and associated with risk for colorectal cancer. The disease is scarcely reported in Nigeria and this is the index report in Ilorin. Two cases were clinically diagnosed in our facility. They both presented with gastrointestinal bleeding and numerous rectal and colonic polyps were identified at colonoscopy. Histological examination of the polyps in both cases revealed features in keeping with adenomatous polyps. This report highlights the occurrence of this precancerous condition.


Subject(s)
Adenomatous Polyposis Coli/diagnosis , Colorectal Neoplasms/diagnosis , Gastrointestinal Hemorrhage/etiology , Adenomatous Polyposis Coli/pathology , Colonoscopy/methods , Colorectal Neoplasms/pathology , Humans , Male , Middle Aged , Nigeria
2.
Niger Med J ; 54(2): 111-4, 2013 Mar.
Article in English | MEDLINE | ID: mdl-23798797

ABSTRACT

BACKGROUND: Colonoscopy is a safe and effective means of visual inspection of the large bowel from the distal rectum to the caecum. It may be carried out for diagnostic and or therapeutic reasons. There is a paucity of data on this procedure in Nigeria. We, therefore, determined the indications, findings, and diagnostic yield in Nigerians at colonoscopy. MATERIALS AND METHODS: This was a hospital-based cross-sectional study carried out at the Endoscopy unit of Crescent hospital, Ilorin from January 2010 to May, 2012. The endoscopy register was reviewed, and the biodata, indications and colonoscopic findings were recorded on a pro forma. RESULTS: A total of 103 patients had colonoscopy. Seventy (68.0%) were males while 33 (32.0%) were females. The indications for colonoscopy were rectal bleeding 41 (39.8%), suspected colon cancer 32 (31.1%), chronic constipation and chronic diarrhoea nine each (8.7%), abdominal/anal pain five (4.9%), suspected anorectal cancer and enterocutaneous fistula two each (1.9%), faecal incontinence, occult gastrointestinal bleeding, post-colostomy for Hirschsprung disease one each (1.0%). Endoscopic findings were normal findings 21 (20.4%), diverticulosis 17 (16.5%), polyps 16 (15.5%), haemorrhoids 16 (15.5%), anorectal cancer 13 (12.6%), angiodysplasia 12 (11.7%), colon cancer eight (7.8%), colitis 7 (6.8%), anorectal ulcer 4 (3.9%), anal warts two (1.9%), anal fissure, caecal tumour, faecal impaction and proctitis one each (1.0%). The diagnostic yield was 79.6%. CONCLUSIONS: The commonest indication for colonoscopy was rectal bleeding, while the most frequent pathology was diverticulosis. The diagnostic yield was high.

3.
Niger. med. j. (Online) ; 54(2): 111-114, 2013.
Article in English | AIM (Africa) | ID: biblio-1267625

ABSTRACT

Colonoscopy is a safe and effective means of visual inspection of the large bowel from the distal rectum to the caecum. It may be carried out for diagnostic and or therapeutic reasons. There is a paucity of data on this procedure in Nigeria. We; therefore; determined the indications; findings; and diagnostic yield in Nigerians at colonoscopy. Materials and Methods: This was a hospital-based cross-sectional study carried out at the Endoscopy unit of Crescent hospital; Ilorin from January 2010 to May; 2012. The endoscopy register was reviewed; and the biodata; indications and colonoscopic findings were recorded on a pro forma. Results: A total of 103 patients had colonoscopy. Seventy (68.0) were males while 33 (32.0) were females. The indications for colonoscopy were rectal bleeding 41 (39.8); suspected colon cancer 32 (31.1); chronic constipation and chronic diarrhoea nine each (8.7); abdominal/anal pain five (4.9); suspected anorectal cancer and enterocutaneous fistula two each (1.9); faecal incontinence; occult gastrointestinal bleeding; post-colostomy for Hirschsprung disease one each (1.0). Endoscopic findings were normal findings 21 (20.4); diverticulosis 17 (16.5); polyps 16 (15.5); haemorrhoids 16 (15.5); anorectal cancer 13 (12.6); angiodysplasia 12 (11.7); colon cancer eight (7.8); colitis 7 (6.8); anorectal ulcer 4 (3.9); anal warts two (1.9); anal fissure; caecal tumour; faecal impaction and proctitis one each (1.0). The diagnostic yield was 79.6. Conclusions: The commonest indication for colonoscopy was rectal bleeding; while the most frequent pathology was diverticulosis. The diagnostic yield was high


Subject(s)
Colonoscopy/methods , Diverticulum , Efficiency/pathology , Gastrointestinal Diseases , Intestinal Diseases
4.
J Bras Pneumol ; 36(3): 325-31, 2010.
Article in English, Portuguese | MEDLINE | ID: mdl-20625670

ABSTRACT

OBJECTIVE: The aim of this study was to determine the factors associated with nocturnal, productive and dry cough among young adults in Nigeria. METHODS: We evaluated 498 subjects, 20-44 years of age, in Ilorin, Nigeria, using the European Community Respiratory Health Survey (ECRHS) questionnaire, administered by trained interviewers. RESULTS: Nocturnal cough was associated with asthma (OR = 10.87; p < 0.01), nasal allergy (OR = 6.33; p < 0.01), smoking (OR = 3.10; p < 0.01), skilled manual and non-manual work (OR = 2.86 and 2.10, respectively; p < 0.01 for both) and female gender (OR = 1.33; p = 0.17). Productive cough was associated with skilled manual and non-manual work (OR = 3.82 and 3.03, respectively; p < 0.01 for both), smoking (OR = 3.10; p < 0.01), asthma (OR = 3.27; p < 0.01) and nasal allergy (OR = 5.81; p < 0.01). Dry cough was associated with asthma (OR =5.18; p < 0.01) obesity (OR =1.88; p = 0.19), smoking (OR = 1.77; p = 1.44), nasal allergy (OR = 1.45; p = 0.26) and female gender (OR =1.36; p = 0.33). Age, gender, type of residence and obesity were not significantly associated with any type of cough (p > 0.05). CONCLUSIONS: Early prevention and treatment of conditions associated with cough, as well as the modification of social factors commonly associated with cough, are needed in order to reduce respiratory morbidity.


Subject(s)
Cough/etiology , Adult , Cough/classification , Cough/epidemiology , Cross-Sectional Studies , Female , Humans , Logistic Models , Male , Nigeria/epidemiology , Young Adult
5.
J. bras. pneumol ; 36(3): 325-331, maio-jun. 2010. tab
Article in English, Portuguese | LILACS | ID: lil-551119

ABSTRACT

OBJETIVO: Determinar os fatores associados à tosse seca, tosse produtiva e tosse noturna entre jovens adultos na Nigéria. MÉTODOS: Foram avaliados 498 indivíduos com 20-44 anos de idade em Ilorin, Nigéria, utilizando-se o questionário European Community Respiratory Health Survey (ECRHS), administrado por entrevistadores treinados. RESULTADOS: A tosse noturna apresentou associações com asma (OR = 10,87; p < 0,01), alergia nasal (OR = 6,33; p < 0,01), tabagismo (OR = 3,10; p < 0,01), trabalho manual e trabalho não manual especializados (OR = 2,86 e 2,10, respectivamente; p < 0,01 para ambos) e gênero feminino (OR = 1,33; p = 0,17). A tosse produtiva apresentou associações com trabalho manual e trabalho não manual especializados (OR = 3,82 e 3,03, respectivamente; p < 0,01 para ambos), tabagismo (OR = 3,10; p < 0,01), asma (OR = 3,27; p < 0,01) e alergia nasal (OR = 5,81; p < 0,01). A tosse seca apresentou associações com asma (OR =5,18; p < 0,01) obesidade (OR =1,88; p = 0,19), tabagismo (OR = 1,77; p = 1,44), alergia nasal (OR = 1,45; p = 0,26) e gênero feminino (OR =1,36; p = 0,33). A idade, o gênero, o tipo de residência e a obesidade não se associaram significativamente a nenhum tipo de tosse (p > 0,05). CONCLUSÕES: A prevenção precoce e o tratamento de condições associadas à tosse, assim como a modificação de fatores sociais comumente associados à tosse, são necessários a fim de reduzir a morbidade respiratória.


OBJECTIVE: The aim of this study was to determine the factors associated with nocturnal, productive and dry cough among young adults in Nigeria. METHODS: We evaluated 498 subjects, 20-44 years of age, in Ilorin, Nigeria, using the European Community Respiratory Health Survey (ECRHS) questionnaire, administered by trained interviewers. RESULTS: Nocturnal cough was associated with asthma (OR = 10.87; p < 0.01), nasal allergy (OR = 6.33; p < 0.01), smoking (OR = 3.10; p < 0.01), skilled manual and non-manual work (OR = 2.86 and 2.10, respectively; p < 0.01 for both) and female gender (OR = 1.33; p = 0.17). Productive cough was associated with skilled manual and non-manual work (OR = 3.82 and 3.03, respectively; p < 0.01 for both), smoking (OR = 3.10; p < 0.01), asthma (OR = 3.27; p < 0.01) and nasal allergy (OR = 5.81; p < 0.01). Dry cough was associated with asthma (OR =5.18; p < 0.01) obesity (OR =1.88; p = 0.19), smoking (OR = 1.77; p = 1.44), nasal allergy (OR = 1.45; p = 0.26) and female gender (OR =1.36; p = 0.33). Age, gender, type of residence and obesity were not significantly associated with any type of cough (p > 0.05). CONCLUSIONS: Early prevention and treatment of conditions associated with cough, as well as the modification of social factors commonly associated with cough, are needed in order to reduce respiratory morbidity.


Subject(s)
Adult , Female , Humans , Male , Young Adult , Cough/etiology , Cross-Sectional Studies , Cough/classification , Cough/epidemiology , Logistic Models , Nigeria/epidemiology , Young Adult
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