ABSTRACT
Chronic liver disease (CLD) is an important condition, diagnosed mainly by liver biopsy and is a leading cause of death among the working class group. It is a major burden in sub-Saharan Africa where it leads to hepatocellular carcinoma with a high mortality. This study was a retrospective one undertaken to determine the safety of performing liver biopsy procedure between January 2000 to January 2009 in terms of the frequency of indications and side effects. A total of 279 entries were found out of which 270 (96.77%) had a definitive liver biopsy histology result. The main indication for liver biopsy was chronic viral hepatitis in 150 patients (53.76%) while the commonest complication was the post-procedure pain that was seen in 16 patients (5.7%). The average duration of hospital stay after biopsy was 6.08 ± 0.52 hours.
Subject(s)
Biopsy/methods , Liver Diseases/pathology , Liver/pathology , Adult , Aged , Ambulatory Care , Biopsy/adverse effects , Chronic Disease , Female , Humans , Liver Diseases/diagnosis , Liver Diseases/epidemiology , Male , Nigeria/epidemiology , Retrospective StudiesABSTRACT
Gastrointestinal stromal tumour (GIST) is a type of tumour that occurs in gastrointestinal (GI) tract, and arises from stroma with no definite cell line of origin and varying pattern of differentiation. It is a type of soft tissue sarcomas. We report a case of a young adult female who was diagnosed with GIST which was found to be unresectable at surgery and was subsequently managed with Imatinib. Treatment with the drug has led to a significant improvement for about 2 years.