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2.
J Pediatr Orthop B ; 33(2): 142-146, 2024 Mar 01.
Article in English | MEDLINE | ID: mdl-37266935

ABSTRACT

The Gartland classification is used to decide on surgery. In contrast, the John Hopkins classification system predicts clinical outcomes for patients undergoing surgery and determines the risk of reduction loss. This study aims to investigate the usability of the Gartland and the John Hopkins classification systems by pediatric and general orthopedic surgeons. The preoperative images of 200 patients who presented at a tertiary-level trauma center with a supracondylar humerus fracture were examined by 4 observers, twice at an interval of 6 weeks. The observers comprised 2 pediatric orthopedic surgeons and 2 orthopedics and traumatology surgeons. Inter- and intra-observer reliability were excellent for the first and second measurements of the Gartland classification. The inter-observer agreement of the pediatric orthopedic surgeons and the general orthopedic surgeons was found to be similar (ICC >90). Inter-observer reliability was excellent (ICC: 0.808) and good (ICC: 0.732) for the measurements of the John Hopkins classification, respectively. The inter-observer agreement of the pediatric orthopedic surgeons and the general orthopedic surgeons was not similar. The inter-observer agreement between the two pediatric orthopedic surgeons was excellent for the measurements (ICC: 0.868; ICC: 0.756, respectively). The inter-observer agreement between the two general orthopedic surgeons was good for the measurements (ICC: 0.605; ICC: 0.663, respectively). The John Hopkins classification system has good intra- and inter-observer reliability, and a high experience level increases the agreement. The Gartland classification system was not affected by experience. This should be considered when taking measurements in studies and patient management.


Subject(s)
Humeral Fractures , Orthopedic Surgeons , Orthopedics , Child , Humans , Reproducibility of Results , Observer Variation , Humeral Fractures/diagnostic imaging , Humeral Fractures/surgery
3.
J Pediatr Orthop ; 43(10): 603-607, 2023.
Article in English | MEDLINE | ID: mdl-37694552

ABSTRACT

BACKGROUND: Rotational malalignment is a common problem in pediatric supracondylar humerus fractures (SCHF). Several techniques have been described to evaluate the true rotation value. Although the Prabhakar and Gordon techniques are used frequently, their superiority to each other in terms of measurement quality is unknown. QUESTIONS/PURPOSES: The aim of this study was to investigate the clinical compatibility of the 2 techniques and to evaluate whether they are suitable for all subtypes. METHODS: This cross-sectional study included 40 patients with SCHF (including subtypes; Typical, Medial Oblique, Lateral Oblique, and High fracture pattern). The Gordon lateral rotation percentage and Prabhakar percentage of metaphyseal overhang were measured twice by 4 experienced Orthopedics and Traumatology surgeons at 8-week intervals. The interobserver and intraobserver reliability were examined using the intraclass correlation coefficient. RESULTS: The interobserver reliability for Gordon and Prabhakar technique was 0.816 and 0.762 for the first measurement and 0.811 and 0.811 for the second measurement, respectively.The medial oblique fracture pattern was determined to have the best interobserver agreement among the subtypes. The result was excellent for the medial and lateral oblique subtypes, good for the typical fracture pattern, and fair for the high fracture pattern. The intraobserver reliability for Gordon and Prabhakar technique was excellent, 0.924 and 0.922, respectively. CONCLUSION: The main finding of this study was that the Gordon and Prabhakar techniques have similar interobserver and intraobserver reliability. Although the Gordon technique tends to have higher interobserver reliability, the difference was clinically insignificant. These measurements should not be relied upon in cases of SCHF with a high fracture pattern because of the different anatomic features of that region. LEVEL OF EVIDENCE: Level III.


Subject(s)
Humeral Fractures , Orthopedic Procedures , Humans , Child , Reproducibility of Results , Cross-Sectional Studies , Radiography , Humeral Fractures/diagnostic imaging , Humeral Fractures/surgery , Observer Variation
4.
Cureus ; 15(8): e44156, 2023 Aug.
Article in English | MEDLINE | ID: mdl-37753050

ABSTRACT

INTRODUCTION: In previous studies, the relationship between BMD (bone mineral density) and LDH (lumbar disc herniation) has been investigated in young people, except for postmenopausal women. The aim of this study was to evaluate this association in postmenopausal women. METHODS: A cross-sectional analysis of 545 consecutive postmenopausal women was performed at a single center. The study included patients aged 45 to 85 with low back pain. Age, weight, height, L1-L4 BMD, L1-L4 T-score, L1-L4 Z-score, femoral neck BMD, femoral neck T-score, and femoral neck Z-score of patients were collected. MRI scans were assessed for the diagnosis of LDH. To explore the impact of the number of herniated segments, patients with LDH were further divided into single-level and multi-level LDH groups. RESULTS: Five hundred and thirteen postmenopausal women were included in the final analysis. The mean age of the patients was 61.3±8.6 years in the LDH group and 58.4±7.8 years in the non-LDH group (p=0.001). The LDH group had higher lumbar (p<0.001) and femoral neck (p<0.05) BMD, T, and Z-scores than the non-LDH group. In binary logistic regression analysis, age, lumbar, and femoral neck BMD were significantly associated with LDH (p<0.001, p=0.03, and p=0.040, respectively). Patients with multi-level herniation had significantly higher rates of obesity (BMI ≥30) compared to patients with single-level herniation (58.0% vs. 47.0%; p=0.031). However, in terms of obesity rates, the LDH group and the non-LDH group were statistically similar (53.9% vs. 54.2%; p=0.961). There was no association between the single and multi-level herniation groups in terms of L1-4 and femoral neck BMD (p=0.760 and 0.435, respectively). CONCLUSION: Higher lumbar bone mineral density and higher femoral neck bone mineral densities were found to be associated with lumber disc herniation in postmenopausal women with low back pain. These results suggest that bone mineral density assessment may be useful in clinical practice to determine which patients are at higher risk of lumbar disc herniation.

5.
J Pediatr Orthop ; 43(9): e734-e741, 2023 Oct 01.
Article in English | MEDLINE | ID: mdl-37470086

ABSTRACT

BACKGROUND: Pediatric physeal ankle fractures carry a high risk of complications. This study aimed to (1) investigate the effect of anatomic reduction of the physis on mid to long-term functional outcomes in Salter-Harris type II and triplane distal tibial physeal fractures (DTPFs) and (2) compare the outcomes of 3 different surgical techniques applied in these fractures. METHODS: The database of a single level-I trauma center was retrospectively reviewed for DTPFs between 2012 and 2022. A total of 39 eligible patients with operative Salter-Harris type II and triplane fractures between 2012 and 2022 were included. Surgical treatment methods were closed reduction-percutaneous fixation (CR-PF), open reduction-screw fixation, or open reduction-plate fixation. Patients were further divided into subgroups for fractures reduced anatomically (<1 mm) or nonanatomically (1 to 3 mm). The primary outcome measures were the American Orthopaedic Foot and Ankle Society Score, ankle range of motion, presence of premature physeal closure and angular deformities, and Takakura ankle osteoarthritis grade. RESULTS: A total of 39 patients were included, with an average age of 12.9 ± 2.2 years. The mean follow-up time was 68.9±38.0 months. The CR-PF group had higher postoperative fracture displacement ( P = 0.011). American Orthopaedic Foot and Ankle Society scores were excellent in all groups, statistically similar between surgical techniques, and similar between anatomic and nonanatomic reduction groups. The CR-PF group ( P =0.030) and nonanatomic reduction ( P = 0.030) provided a significantly lower ankle osteoarthritis rate. All 4 patients with premature physeal closure were observed in patients treated with open techniques. CONCLUSIONS: CR-PF for the treatment of DTPFs should be preferred in suitable cases as it is less invasive and provides satisfactory mid to long-term functional outcomes without increasing complications compared with anatomic reduction and open techniques. LEVEL OF EVIDENCE: Level III.


Subject(s)
Ankle Fractures , Fractures, Closed , Fractures, Multiple , Salter-Harris Fractures , Tibial Fractures , Humans , Child , Adolescent , Ankle Fractures/diagnostic imaging , Ankle Fractures/surgery , Ankle Fractures/complications , Ankle , Retrospective Studies , Tibial Fractures/diagnostic imaging , Tibial Fractures/surgery , Tibial Fractures/complications , Growth Plate/surgery , Fractures, Closed/complications , Fracture Fixation, Internal/methods , Fractures, Multiple/complications , Salter-Harris Fractures/complications
6.
Cureus ; 15(5): e39493, 2023 May.
Article in English | MEDLINE | ID: mdl-37362477

ABSTRACT

BACKGROUND AND OBJECTIVES:  The COVID-19 pandemic has had a negative impact on healthcare in musculoskeletal pathology. There is no standard protocol for pathology services during a pandemic. The study aimed to assess the impact of COVID-19 restrictions on the workload of the musculoskeletal pathology service and the hurdles faced in collaboration with the orthopedic oncology unit in a tertiary reference center in a developing country. MATERIALS AND METHODS:  The pathology reports from mid-March to mid-June 2019, 2020, and 2021 were retrospectively reviewed. RESULTS:  Significant differences were found between the pandemic period (2020) and the non-pandemic periods (2019-2021) in benign bone and soft tissue lesions, resection surgeries, and soft tissue tumors, which were more prevalent in the non-pandemic periods. However, there was no significant decrease in biopsy procedures. Conclusion: During the pandemic period, the biopsy procedure appears to be feasible for bone and soft tissue lesions without the need for anesthesia.

7.
J Pediatr Orthop ; 43(3): 135-142, 2023 03 01.
Article in English | MEDLINE | ID: mdl-36730034

ABSTRACT

BACKGROUND: Olecranon fractures are rare conditions in childhood. The aim of this study was to investigate the factors affecting the results in surgically treated pediatric and adolescent olecranon fractures. METHODS: The orthopaedic trauma database of a large academic tertiary center was retrospectively searched for patients who had sustained an olecranon fracture and were treated surgically between 2005 and 2021. Data related to demographic features, additional fractures, and the presence of any disease were obtained from the patient files. Mayo elbow performance score and the Turkish-language version of the shortened version of the disabilities of arm, shoulder, and hand scale were the main functional outcome measurements. RESULTS: The study included 37 elbows of 34 patients with an average age at the time of surgery of 10.9±3.1 years. The mean follow-up period was 78.2±48.0 months (range, 12 to 196 mo). The 1-year fracture rate of contralateral olecranon was 75% in osteogenesis imperfecta patients. Concomitant fractures were 7 proximal radius, 1 medial epicondyle, and 2 capitellum fractures. The surgical treatment methods were tension band wiring (TBW), open reduction and isolated K-wire fixation, closed reduction and percutaneous fixation (CR-PP), and open reduction-plate fixation. The mean implant removal time in patients treated with closed reduction and percutaneous fixation was 2.2 months, open reduction and isolated K-wire fixation 4.7 months, and TBW 12.7 months ( P =0.004). The mean disabilities of arm, shoulder, and hand scale was 1.9. The mean Mayo elbow performance score was 100. Grade 1 elbow arthritis was determined in 3 patients. No patient underwent revision surgery. CONCLUSIONS: All treatment modalities provided excellent long-term functional results and low complication rates without the need for revision. Closed reduction-percutaneous fixation and open reduction-isolated K-wire fixation were associated with shorter implant removal times compared with TBW. LEVEL OF EVIDENCE: Level III.


Subject(s)
Elbow Joint , Olecranon Fracture , Olecranon Process , Ulna Fractures , Humans , Adolescent , Child , Retrospective Studies , Ulna Fractures/surgery , Fracture Fixation, Internal/adverse effects , Fracture Fixation, Internal/methods , Elbow Joint/surgery , Olecranon Process/surgery , Olecranon Process/injuries , Bone Wires , Treatment Outcome
8.
Jt Dis Relat Surg ; 33(1): 208-215, 2022.
Article in English | MEDLINE | ID: mdl-35361097

ABSTRACT

OBJECTIVES: This study aimed to present the clinical and radiological results of a large patient group operated by Tönnis lateral acetabuloplasty (TLA) for developmental dysplasia of the hip (DDH). PATIENTS AND METHODS: The retrospective study was conducted with 66 hips of 41 patients (5 males, 36 females; mean age: 32.3±18 months; range, 11 to 132 months) operated for DDH using the TLA technique in a single center between February 2012 and December 2016. Adductor tenotomy was performed on 52 (79%) hips. There was a need for additional femoral shortening and derotation-varization osteotomy in 14 (21%) hips. Clinical outcomes were evaluated with modified McKay criteria. The acetabular index and lateral migration index for the subluxated hip were calculated, and the femoral head position was evaluated according to Perkin's line and Shenton's line. The Severin classification was used to assess the outcome of the hips. RESULTS: The mean follow-up period was 27±11 months. According to the modified McKay criteria for DDH, 77.3% of hips were classified as excellent, 16.6% as good, and 6.1% as fair. The mean acetabular index decreased from 36.1° preoperatively to 18.6° postoperatively. The mean postoperative improvement for the acetabular index was 17.5±5. The lateral migration index improved from 89.7 to 10.6%. A statistically significant difference was determined between the preoperative and postoperative measurements of the acetabular index and lateral migration index (p<0.001). CONCLUSION: Tönnis lateral acetabuloplasty was found to be safe and effective with a low learning curve, and successful treatment decreases the duration of follow-up required in patients with DDH.


Subject(s)
Acetabuloplasty , Developmental Dysplasia of the Hip , Acetabuloplasty/methods , Child , Child, Preschool , Developmental Dysplasia of the Hip/diagnostic imaging , Developmental Dysplasia of the Hip/surgery , Female , Hip , Humans , Infant , Male , Retrospective Studies , Treatment Outcome
9.
Indian J Orthop ; 56(4): 587-591, 2022 Apr.
Article in English | MEDLINE | ID: mdl-35342522

ABSTRACT

Introduction: Traumatic hip dislocation in childhood is a rare injury. The aim of this study was to present the experience of a single center for traumatic hip dislocation in the pediatric and adolescent age group. Materials and Methods: The orthopedic trauma database of a single center was retrospectively searched for patients who had sustained a traumatic hip dislocation between 2004 and 2019. Data related to age, mechanism of injury, additional fractures, presence of any open fracture or neurovascular injury, and dislocation side were retrieved from the patient files. Functional outcome was evaluated using the Harris Hip Scoring system. Results: The mean age of 13 patients at the time of injury was 7.7 years and the mean follow-up time was 124.5 months (10.4 years). All traumatic hip dislocations were posterior dislocations. The mean Harris Hip score was 95.7 points (range 55-100 points) with 12 patients scored as excellent and 1 as poor results. Ten complications including limb length inequality, avascular necrosis and hip arthritis were determined in seven patients. Conclusion: Traumatic hip dislocation is a rare injury in the pediatric age group. Early diagnosis and concentric reduction of the femoral head is essential for better functional results and to avoid complications. Limb length inequality is a frequently seen complication, which has not been reported in previous studies.

10.
Eur J Trauma Emerg Surg ; 48(1): 351-356, 2022 Feb.
Article in English | MEDLINE | ID: mdl-33641043

ABSTRACT

PURPOSE: This study aimed to investigate the efficiency and safety of tranexamic acid use in open reduction and internal fixation of pelvis and acetabulum fractures. MATERIALS AND METHODS: 73 consecutive patients were included. 1000 mg TXA was administered intravenously to all patients before surgery. The patients were evaluated on the basis of preoperative, postoperative first and third day hemoglobin-hematocrit values, amount of drainage collected, total blood loss, transfusion rates and complications. RESULTS: Mean operative time was 120.1 min. Average decrease in hematocrit levels between preoperative and postoperative first day was 2.1 g/dL. Average collected blood from the drain was 177 mL. Mean total blood loss was 1137 mL. Transfusion rate of the patients was 21%. Mean transfused units was 0.9 units. Three patients died within 3 weeks after the operation due to myocardial infarction, acute kidney failure and pneumonia. There were no cases of symptomatic venous or pulmonary thromboembolism during the 90 days of follow-up. CONCLUSION: Use of TXA in pelvic and acetabular fractures was found to be effective in reducing total blood loss, hemoglobin drop and transfusion rates without increasing venous and pulmonary thromboembolism in our series.


Subject(s)
Antifibrinolytic Agents , Hip Fractures , Tranexamic Acid , Antifibrinolytic Agents/therapeutic use , Blood Loss, Surgical/prevention & control , Humans , Pelvis , Tranexamic Acid/therapeutic use
11.
Indian J Orthop ; 55(Suppl 2): 323-329, 2021 Jul.
Article in English | MEDLINE | ID: mdl-34306544

ABSTRACT

BACKGROUND: Intramedullary nailing is the most preferred fixation method for diaphyseal radius and ulna fractures in the young age group. The aim of this study was to compare the dorsal and lateral entry points in the context of entry site-related complications, fracture union and functional results. METHODS: This retrospective comparative study included pediatric patients who underwent surgery for isolated diaphyseal radius or both bone forearm fractures with intramedullary nailing using Kirschner wire between January 2013 and January 2019. K-wire was introduced from the distal radius through dorsal entry (Group A) in 19 patients and lateral entry (Group B) in 18 patients. The mean follow-up was 37 months. Complications were noted and functional outcomes were evaluated according to the CHOP criteria. RESULTS: All fractures were healed. The functional results were determined to be excellent for 30, fair for 4, and poor for 3 patients. The overall complication rate was 18.9%, including distal radius fracture, mild pain in the wrist, and minor loss in ROM. No statistically significant differences were determined between the groups in respect of functional results and complication rates. CONCLUSION: Good functional results and similar complication rates can be obtained with both dorsal and lateral entry approaches. Stainless steel K-wire is an inexpensive intramedullary fixation implant option, which provides strong stabilization. Distal radius fracture is a newly reported complication for forearm intramedullary nailing. Leaving the implant out of the skin seems safe with the benefit of avoiding a further surgical intervention to extract the implant.

12.
Acta Orthop Belg ; 85(1): 79-85, 2019 Mar.
Article in English | MEDLINE | ID: mdl-31023203

ABSTRACT

The amount of displacement in medial epicondylar fracture is one of the most important criteria for treatment decision. The displacement of medial epicondyle fractures of the humerus may be underestimated by standard AP and lateral views of elbow. The aim of the current study is to show the clinical relavance of computerized tomography (CT) for medial epicondyle fractures. A retrospective analysis on patients with medial epicondyle fracture was performed. Measurements were performed by 9 reviewer, there were 12 cases available for review with both radiographs and CT. The difference between measurement of AP Xray versus frontal and axial CT scans was found to be statistically significant for 1st and 2nd assessments (p=0.001). The decision for operative treatment was higher after evaluation with CT for both first and second assessment and this was statistically significant (p=0,0001). CT is found to be superior to determine the real amount of the fracture displacement and was relavant for treatment decision of pediatric medial epicondylar fractures. We also found a better interobserver agreement for axial CT scans relative to treatment decision. Level of evidence : IV.


Subject(s)
Decision Making , Humeral Fractures/diagnostic imaging , Tomography, X-Ray Computed , Adolescent , Child , Female , Humans , Humeral Fractures/surgery , Male , Retrospective Studies
13.
J Paediatr Child Health ; 55(2): 168-174, 2019 Feb.
Article in English | MEDLINE | ID: mdl-30069945

ABSTRACT

AIM: The aim of the present study was to examine if there were gender differences in risk factors in 4415 infants who were evaluated through a physical examination and hip ultrasonography (USG). METHODS: Physical examination of the hip and hip USG were performed on 4415 infants by the same paediatric orthopaedics specialist. Barlow and Ortolani tests were performed together with the evaluation for the limitation of abduction. Ultrasonographic hip examination was performed according to the Graf technique. The birth records of all the infants were examined, and anamneses (genetic disease, maternal age, delivery type, swaddling, multiple pregnancies, duration of gestation period, gravida, birthweight, breech presentation, oligohydramnios and family history) were obtained from the families. Any accompanying musculoskeletal (torticollis, pes equinovarus, congenital knee dislocation) abnormality was recorded. RESULTS: Pathological hip was determined in 149 (3.37%) of 4415 infants. In males, gestational week, family history, breech presentation, swaddling, congenital knee dislocation and limited abduction were observed to be significant for the presence of developmental dysplasia of the hip (DDH). In females, significant factors for the presence of DDH were determined to include birthweight, gestational week, breech presentation, multiple pregnancy, accompanying oligohydramnios, torticollis, pes equinovarus and limited abduction. CONCLUSION: Risk factors for DDH can differ according to gender.


Subject(s)
Hip Dislocation, Congenital/diagnostic imaging , Hip Dislocation, Congenital/etiology , Child, Preschool , Female , Humans , Infant , Infant, Newborn , Male , Neonatal Screening , Physical Examination , Risk Factors , Sex Factors , Ultrasonography
14.
J Pediatr Orthop ; 38(8): e424-e428, 2018 Sep.
Article in English | MEDLINE | ID: mdl-29917008

ABSTRACT

BACKGROUND: Capitellum fractures are rare in adolescents, and information in literature is still limited. The purpose of this study was to report the mid-term and long-term functional and radiographic results of 13 surgically treated adolescent capitellum fractures in a level I trauma center. METHODS: This retrospective study included patients aged 10 to 16 years, who underwent surgery for a capitellum fracture and were followed up for at least 12 months. Fractures were classified according to the McKee modification of the Bryan and Morrey classification, and elbow arthritis was classified using the Broberg and Morrey system. Functional outcomes were assessed with the Mayo Elbow Performance Index (MEPI) and the Turkish-language version of the shortened version of the Disabilities of Arm, Shoulder, and Hand (QuickDASH) scale. RESULTS: The mean time to surgical intervention was 4.5 days (range, 1 to 18 d). The mean flexion-extension range of motion arc was measured as 115 (range, 45 to 150) degrees. The mean restriction for extension and flexion compared with the uninjured side was measured as 10.7 (range, 0 to 45) and 11.5 (range, 0 to 45) degrees, respectively. The mean MEPI was 87.7 points (range, 50 to 100 points) with 9 patients as excellent, 1 good, 1 fair, and 2 poor results. The mean QuickDASH score was 11 (range, 0 to 57). The mean MEPI score was 95.6 and 75 and the mean QuickDASH score was 2.62 and 25.0 for early surgery group (≤3 d) and late surgery group (>3 d), respectively (P=0.073, 0.024). Elbow joint contracture developed in 4 patients. Implant removal and open release of joint contracture was applied to 2 patients. Elbow arthritis of grade 3 was observed in 2 patients and grade 2 in 1 patient. CONCLUSIONS: Capitellum fractures may be easily missed on conventional radiographs, if not suspected. Delayed diagnosis may lead to a worsening of the functional outcomes. Computerized tomography is helpful in the determination of these fractures. Early diagnosis and a well-performed surgery is essential for successful outcome. LEVEL OF EVIDENCE: Level IV-case series.


Subject(s)
Elbow Injuries , Fracture Fixation, Internal/statistics & numerical data , Humeral Fractures/surgery , Adolescent , Child , Contracture , Elbow Joint/diagnostic imaging , Elbow Joint/surgery , Female , Humans , Male , Postoperative Complications , Radiography , Range of Motion, Articular , Retrospective Studies , Treatment Outcome
15.
Injury ; 49(2): 398-403, 2018 Feb.
Article in English | MEDLINE | ID: mdl-29198374

ABSTRACT

INTRODUCTION: Hoffa fractures are rare injuries and usually involve the lateral condyle. There are few published studies of large series of isolated coronal plane fractures of the femoral condyle. The aim of the study to determine the long-term functional outcomes and complications in surgically treated Hoffa fractures. PATIENTS AND METHODS: A retrospective review was made of 13 consecutive patients who were treated surgically for an isolated coronal plane fracture of the distal femur posterior condyle. The patients were evaluated with physical examination, PA and lateral radiographs and CT at the final follow-up examination. Functional outcome was evaluated with the OXFORD knee scoring system and Knee Society Score (KSS). Pain at rest and in activity was assessed using a Visual Analog Scale (VAS). RESULTS: The patients comprised 11 males and 2 females with an average age at surgery of 27.5 years. The mean follow-up period was 93 months (range, 62-134 months). Mean time to fracture healing was 10 weeks (range, 8-12 weeks). The mean ROM was determined as 110°, mean KSS 78,4 and mean Oxford knee score 38,2. The mean KSS was 66,5 for medial Hoffa fracture patients and it was 83,8 for lateral Hoffa fracture patients. The mean Oxford knee score was 33,2 for medial Hoffa fracture patients and it was 40,4 for lateral Hoffa fracture patients. The mean VAS at rest and in activity was 1,1 and 2,9, respectively. Osteoarthritis was seen in 7 (54%) patients and avascular necrosis in 2 (15.4%). Varus instability was determined in 1 patient and valgus instability in 1 patient. CONCLUSION: Hoffa fractures may easily be overlooked if the radiological examination is not made carefully. Screw fixation was seen to provide enough biomechanical stability until the fracture healed. Arthrosis is a frequent long-term complication which worsens the functional results. Medial Hoffa fractures tend to have worse functional results than lateral Hoffa fractures. LEVEL OF EVIDENCE: Therapeutic Level IV retrospective case series.


Subject(s)
Femoral Fractures/surgery , Fracture Fixation, Internal , Fracture Healing/physiology , Intra-Articular Fractures/surgery , Range of Motion, Articular/physiology , Adult , Bone Plates , Bone Screws , Female , Femoral Fractures/physiopathology , Fracture Fixation, Internal/rehabilitation , Humans , Intra-Articular Fractures/physiopathology , Male , Prognosis , Radiography , Retrospective Studies , Treatment Outcome , Visual Analog Scale , Young Adult
16.
J Pediatr Orthop B ; 26(1): 5-13, 2017 Jan.
Article in English | MEDLINE | ID: mdl-27341120

ABSTRACT

Functional and radiographic outcomes, in addition to complication and reoperation rates of open curettage and grafting without instrumentation or with intramedullary nailing, in the treatment of simple bone cysts (SBCs) of the humerus were compared. Thirty-seven children [25 males, 12 females; median age=9.5 years (range, 3-17 years)] with humeral SBC were treated with curettage and grafting without instrumentation (group 1, 21 patients) or with intramedullary nailing (group 2, 16 patients). The pathological fracture rate was 85.7% in group 1 and 87.5 in group 2. The follow-up duration ranged from 26 to 85 months. The average last follow-up Musculoskeletal Tumor Society functional scores for groups 1 and 2 were 28.9 and 29.5 (P>0.05). Higher, but statistically insignificant (P>0.05), complete or significant partial radiographic healing rates were achieved in group 2 (100%) compared with group 1 (76.2%). The overall complication rate of the entire study population was 21.6% (19%; 4/21 in group 1; 25%; 4/16 in group 2). The reoperation rates for groups 1 and 2 were 9.5% (2/21; one for partial cyst healing, one for recurrence) and 56.25% (9/16; one for surgical complication, eight for implant removal). Surgical intervention is indicated for selected patients with SBCs. Even though perfect functional results were possible with open curettage and grafting, continuous intramedullary decompression with elastic nails led to a higher radiographic healing rate in the treatment of humeral SBCs. Open curettage and grafting with or without intramedullary nailing was associated with a high number of complications, but the rate of reoperation for complications was very low.


Subject(s)
Bone Cysts/surgery , Bone Neoplasms/surgery , Bone Transplantation/adverse effects , Fracture Fixation, Intramedullary/methods , Neoplasm Recurrence, Local/surgery , Adolescent , Bone Nails/adverse effects , Bone Neoplasms/pathology , Child , Child, Preschool , Curettage , Decompression, Surgical/methods , Female , Femur/surgery , Fractures, Spontaneous/etiology , Humans , Humeral Fractures/surgery , Humerus/surgery , Male , Neoplasm Recurrence, Local/pathology , Pain, Postoperative , Retrospective Studies
17.
Curr Pharm Biotechnol ; 17(10): 866-72, 2016.
Article in English | MEDLINE | ID: mdl-27194356

ABSTRACT

This is a literature review of studies focusing on the preparation of hydrogels for use as oncological drug delivery systems in the treatment of osteosarcoma (OS). The databases of the US National Library of Medicine National Institutes of Health, Embase, OVID, and Cochrane Library, and the references of retrieved studies, were traced from 1843 to December 21, 2015, without language restrictions. The obtained data were evaluated by complementary statistical methods. Potentially relevant studies were found and included in the analysis. OS-specific chemotherapeutic agents can be successfully embedded within the hydrogels and these drug-loaded hydrogels can be applied locally, rather than systemically, without organ tissue toxicity. Further, OS-specific drug-loaded hydrogels significantly increased tumor inhibition and decreased osteolysis and lung metastases. Drug-loaded hydrogels could be useful in the treatment of OS, although their development remains at the experimental phase. Following evaluation of their application in surgery and the completion of drug release kinetics studies, drug-loaded hydrogels could be tested on living mammals in large samples with the aim of applying these in clinical settings. In the future, development of such drug delivery systems and application of targeted approaches against osteosarcoma and other malignancies may render surgery, radiotherapy and chemotherapy unnecessary.


Subject(s)
Antineoplastic Agents/administration & dosage , Bone Neoplasms/drug therapy , Drug Delivery Systems/methods , Hydrogels/chemistry , Osteosarcoma/drug therapy , Animals , Antineoplastic Agents/therapeutic use , Drug Liberation , Humans , United States
18.
Indian J Orthop ; 50(1): 65-9, 2016.
Article in English | MEDLINE | ID: mdl-26955179

ABSTRACT

BACKGROUND: Results of open and endoscopic carpal tunnel surgery were compared with many studies done previously. To the best of our knowledge, difference in pain after endoscopic carpal tunnel release (ECTR) and open carpal tunnel release (OCTR) has not been objectively documented in literature. The aim of the study was to compare the pain intensity in the early postoperative period in patients undergoing OCTR versus those undergoing ECTR. MATERIALS AND METHODS: Fifty patients diagnosed with carpal tunnel syndrome were randomized into two groups using "random number generator" software (Research Randomizer, version 3.0); endoscopic surgery group [(21 female, 1 male; mean age 49 years (range 31-64 years)] and open surgery group [(25 female, 3 male; mean age 45.1 years (range 29-68 years)] and received carpal tunnel release. Surgery was performed under regional intravenous anesthesia. The patients' pain level was assessed at the 1(st), 2(nd), 4(th), and 24(th) postoperative hours using a visual analog scale (VAS) score. RESULTS: Mean age, gender and duration of symptoms were found similar for both groups. Boston functional scores were improved for both groups (P < 0.001, P < 0.001). Pain assessment at the postoperative 1(st), 2(nd), 4(th) and 24(th) hours revealed significantly low VAS scores in the endoscopic surgery group (P = 0.003, P < 0.001, P < 0.001, P < 0.001). Need for analgesic medication was significantly lower in the endoscopic surgery group (P < 0.001). CONCLUSION: Endoscopic carpal tunnel surgery is an effective treatment method in carpal tunnel release vis-a-vis postoperative pain relief.

19.
Acta Orthop Traumatol Turc ; 50(2): 178-85, 2016.
Article in English | MEDLINE | ID: mdl-26969953

ABSTRACT

OBJECTIVE: The purpose of this study was to assess the outcomes of patients who had been treated by a modified Harrington procedure for advanced periacetabular metastases. METHODS: Between 2006 and 2013, 16 patients with a mean age of 57 years (range: 28-73 years) were treated using a modified Harrington technique. Extensive (class II/III) periacetabular defects were due to metastatic carcinoma or multiple myeloma. Surgical procedure included total hip replacement and acetabular reconstruction using threaded pins, cemented acetabular reinforcement ring, and/or polyethylene cup. RESULTS: All patients improved in regard to pain and walking ability. Mean preoperative and postoperative Musculoskeletal Tumour Society (MSTS) functional scores were 52.8% (range: 33.3-73.3%) and 72% (range: 56.6-90%), respectively (p<0.05). There were 5 (31%) early or late complications requiring additional surgery. Implant survival was 75% and 37.5% at 12 and 18 months, respectively. Mean survival of the patients was 21 months (range: <1-6 years). Six remained alive, with a mean survival of 27 months (range: 18 months to 5 years). CONCLUSION: This modified Harrington procedure can be used for reconstruction of advanced periacetabular metastatic lesions.


Subject(s)
Acetabulum/surgery , Arthroplasty, Replacement, Hip/methods , Bone Neoplasms/secondary , Bone Neoplasms/therapy , Plastic Surgery Procedures/methods , Adult , Aged , Female , Humans , Kaplan-Meier Estimate , Male , Middle Aged , Pelvis/diagnostic imaging , Radiography , Radiotherapy , Turkey
20.
Acta Orthop Belg ; 81(3): 530-7, 2015 Sep.
Article in English | MEDLINE | ID: mdl-26435250

ABSTRACT

The objective of this retrospective study was to evaluate clinical outcomes, local recurrence and complication rates of antihelminthic chemotherapy and wide resection in patients with muscle or bone hydatidosis. The authors treated 10 patients (6 females, 4 males) between 2004 and 2012: 8 with muscle and 2 with bone hydatidosis. The mean age at surgery was 42.5 years (range, 11-66 years). All patients were treated with wide resection and pre- and postoperative chemotherapy with albendazole. The mean follow-up was 64 months (range, 28-120 months). All patients achieved satisfactory clinical outcomes. There were no local recurrences. Surgical complications were seen in 3 patients (30%) : one superficial infection, one deep infection, and one hematoma. Two (20%) required additional surgery. An aggressive oncological approach, consisting of antihelminthic chemotherapy and wide resection, can provide favorable clinical outcomes and prevent local recurrence in patients with musculoskeletal hydatidosis. Potential complications of aggressive surgery should be preferred to potential morbidity of local and systemic dissemination.


Subject(s)
Albendazole/therapeutic use , Bone Diseases, Infectious/therapy , Echinococcosis/therapy , Myositis/therapy , Orthopedic Procedures/methods , Adolescent , Adult , Aged , Animals , Anthelmintics/therapeutic use , Bone Diseases, Infectious/diagnosis , Bone Diseases, Infectious/parasitology , Bone and Bones/parasitology , Child , Diagnosis, Differential , Echinococcosis/diagnosis , Echinococcosis/parasitology , Echinococcus granulosus/isolation & purification , Female , Follow-Up Studies , Humans , Magnetic Resonance Imaging , Male , Middle Aged , Muscle, Skeletal/parasitology , Myositis/diagnosis , Myositis/parasitology , Retrospective Studies , Time Factors , Tomography, X-Ray Computed , Treatment Outcome , Young Adult
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