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Article in Russian | MEDLINE | ID: mdl-2686319

ABSTRACT

Clinical investigation was performed and dopamine metabolism (renal catecholamine excretion) studied in 29 children and 5 adults with various forms of CP, 5 myasthenic children and 1 child with Strümpel disease treated with Nakom. The therapy was judged expedient in 20% of the cases of pronounced muscular rigidity and dystonia with decreased dopamine excretion. The drug proved ineffective in atonic, astatic, severe hyperkinetic arms, and in cases with severe psycho-organic signs.


Subject(s)
Carbidopa/therapeutic use , Cerebral Palsy/drug therapy , Dystonia Musculorum Deformans/drug therapy , Levodopa/therapeutic use , Myasthenia Gravis/drug therapy , Adolescent , Adult , Age Factors , Catecholamines/urine , Cerebral Palsy/urine , Child , Child, Preschool , Clinical Trials as Topic , Drug Combinations/therapeutic use , Dystonia Musculorum Deformans/urine , Humans , Muscle Rigidity/drug therapy , Muscle Rigidity/urine , Myasthenia Gravis/urine
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