ABSTRACT
OBJECTIVE: To assess the effect of low-level laser therapy (LLLT) on the incorporation of deep-frozen block allografts in a rabbit model. BACKGROUND DATA: Studies have shown that LLLT has beneficial effects on tissue repair and new bone formation. METHODS: Bone tissue was harvested from two rabbits, processed by deep-freezing and grafted into the calvaria of 12 animals, which were then randomly allocated into two groups: experimental (L) and control (C). Rabbits in group L were irradiated with an aluminum gallium arsenide diode laser (AlGaAs; wavelength 830 nm, 4 J/cm(2)), applied to four sites on the calvaria, for a total dose of 16 J/cm(2) per session. The total treatment dose after eight sessions was 128 J/cm(2). Animals were euthanized at 35 (n = 6) or 70 days (n = 6) postoperatively. RESULTS: Deep-freeze-processed block allografts followed by LLLT showed incorporation at the graft-host interface, moderate bone remodeling, partial filling of osteocyte lacunae, less inflammatory infiltrate in the early postoperative period, and higher collagen deposition than the control group. CONCLUSION: Optical microscopy and scanning electron microscopy showed that allograft bone processed by deep-freezing plus LLLT is suitable as an alternative for the treatment of bone defects. Use of the deep-freezing method for processing of bone grafts preserves the structural and osteoconductive characteristics of bone tissue.
Subject(s)
Low-Level Light Therapy , Osteogenesis/radiation effects , Transplantation, Homologous , Animals , Bone Transplantation , Humans , Male , Microscopy, Electron, Scanning , Rabbits , Skull/growth & development , Skull/radiation effectsABSTRACT
CONTEXT: Trauma has been an important public health problem worldwide. Facial injuries are among the most common types of trauma treated at emergency departments, associated or not with injuries in other anatomic sites. The patterns of facial fractures are usually affected by geography and socioeconomic conditions. AIM: To investigate the prevalence of facial fractures in Lages, state of Santa Catarina, southern Brazil, from September 2003 to August 2008. SETTINGS AND DESIGN: Cross-sectional, retrospective, epidemiological study. MATERIALS AND METHODS: Data on patients' gender, age, etiological agent, and facial region affected by fracture were collected from the charts of patients treated with facial fractures. STATISTICAL ANALYSIS USED: Qualitative variables were expressed as absolute and relative frequencies, and quantitative variables as means and standard deviation. The Chi-square test was used to evaluate the association between gender, traffic accidents and facial region affected. The association between etiological agents and facial region affected was assessed using the chi-square test and the adjusted residuals analysis. RESULTS: 492 patients presented with oral and maxillofacial trauma, with 988 facial fractures; 80.9% of the patients were men, and the most frequent age group was 21-30 years (29.5%). The most frequent causes of fractures were: Traffic accidents in 27.9%, physical assault in 14.9%, and bicycle falls in 10.5%; several other causes scored below 10%. CONCLUSION: Regular publication of epidemiological data is extremely important for the implementation of prevention campaigns and for an increased awareness of the etiology of fractures affecting the face and other anatomic sites.
Subject(s)
Facial Bones/injuries , Skull Fractures/epidemiology , Accidents, Traffic/statistics & numerical data , Adolescent , Adult , Age Factors , Aged , Aged, 80 and over , Bicycling/injuries , Brazil/epidemiology , Child , Cross-Sectional Studies , Epidemiologic Studies , Female , Hospitalization/statistics & numerical data , Humans , Male , Mandibular Fractures/epidemiology , Maxillary Fractures/epidemiology , Middle Aged , Nasal Bone/injuries , Occupational Injuries/epidemiology , Residence Characteristics/statistics & numerical data , Retrospective Studies , Seasons , Sex Factors , Violence/statistics & numerical data , Young Adult , Zygomatic Fractures/epidemiologyABSTRACT
Com o intuito de incentivar novos estudos epidemiológicos e proporcionar o conhecimento da realidade atual das fraturas faciais na cidade de Lages e região (Santa Catarina), como também o de criar um banco de dados que servirá de base para a criação e melhoramento de programas de atendimento médico-odontológicos estimulando programas preventivos do trauma facial, desta forma, realizou-se este estudo epidemiológico onde se procurou avaliar os pacientes admitidos no serviço de cirurgia e traumatologia bucomaxilofacial do Hospital Nossa Senhora dos Prazeres, no período de setembro de 2003 a agosto de 2008, levando-se em consideração os agentes etiológicos, a região fraturada do esqueleto facial, em relação ao gênero masculino e feminino, idade e procedência. Dos 492 pacientes admitidos no período estudado, observou-se 988 fraturas faciais, sendo que ocorridas no osso mandibular foram as mais frequentes, seguidas das fraturas no complexo zigomático. Os pacientes do gênero masculino, sofreram no mínimo 4 vezes mais traumatismos de face, que os pacientes do gênero feminino. A faixa etária mais atingida foi dos 21 aos 30 anos de idade, seguidos do grupo dos 31 aos 40 anos de idade. Dentre os agentes etiológicos, os que mais ocasionaram fraturas faciais, foi acidente automobilístico, seguido de agressão física e queda de bicicleta
Subject(s)
Male , Female , Humans , Dentistry , Facial InjuriesABSTRACT
Relataremos um caso de carcinoma epidermóide metastático em glândula submandibular. Paciente, leucoderna, aposentado, 72 anos, apresentava aumento de volume, em regiäo submandibular. A história médica do paciente constava de uma cirurgia de biópsia de lábio inferior, lado esquerdo. Buscamos o resultado histopatológico (de 4 anos atrás) desta lesäo e constatamos o diagnóstico de carcinoma epidermóide, moderadamente diferenciado para um fragmento e bem diferenciado para o outro. Solicitamos tomografia computadorizada da regiäo submandibular e foi constatado grande aumento de volume da glândular submandibular esquerda (em torno de 6 cm de diâmetro), sem comprometimento de linfonodos. Após a excisäo cirúrgica total da glândula e o encaminhamento para o histopatológico, o diagnóstico foi de carcinoma epidermóide metastático grau II; esta metástase proveniente da regiäo primária, o lábio inferior. A raridade deste caso, além de o carcinoma epidermóide ser incomum em glândula submandibular, deve-se ao fato de que, geralmente, o carcinoma epidermóide de lábio inferior dá metástase para os linfonodos submentonianos, submandibulares e/ou cervicais profundos e, neste caso específico, a metástase ocorreu na glândula submandibular
