ABSTRACT
Zinc (Zn) plating/stripping is a promising anodic electrochemical reaction for aqueous batteries because of its high safety, low cost, two electron transfer, and rapid reaction kinetics. However, the notorious dendrite growth of Zn has become one of the biggest obstacles hindering its further commercialization. A multifunctional binder-free tin (Sn)-modified 3D carbon felt anodic host (SH) is constructed for aqueous zinc-based flow batteries (ZFB) via a facile and scalable strategy. Compared with the pristine carbon felt host (PH), the as-fabricated SH affords more robust Zn nucleation sites, lower hydrogen evolution reaction potential and lower nucleation overpotential of Zn and thus better induces uniform Zn plating/stripping with very high Coulombic efficiency (CE). Based on such an SH, a symmetrical flow battery exhibits superior CE (290 cycles with average CE of 99.4%) and a zinc-bromine flow battery demonstrates a longer cycle life (142 cycles with average CE of 97.2%), much better than pristine PH. This is a simple, novel, and effective way to suppress Zn dendrites and improve the performance of ZFBs.
ABSTRACT
The relationship between SAP2 activity and drug resistance in Candida albicans was investigated by using itraconazole-resistant and itraconazole-sensitive C. albicans isolates. The precipitation zones were measured to analyze SAP2 activity. Mice were classified into itraconazole-resistant and -sensitive C. albicans isolate groups, and a control group, with their survival and mortality rate being observed over 30 days. The relative expression levels of CDR1, CDR2, MDR1, and SAP2 were measured using RT-PCR. It was found that the secreted aspartyl proteinase activity of itraconazole-resistant C. albicans strains was significantly higher than that of itraconazole-sensitive C. albicans strains (P < 0.001). A significantly higher mortality rate was recorded for mice treated with itraconazole-resistant C. albicans than for mice treated with itraconazole-sensitive C. albicans. In regards to the CDR1, CDR2, and MDR1 genes, there was no significant difference between the 2 groups of mice. Positive correlations between SAP2 and MDR1 and between CDR1 and CDR2 were found. The high expression level of SAP2 may relate to the virulence, pathogenicity, and resistance of C. albicans.