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1.
World J Gastroenterol ; 28(32): 4540-4556, 2022 Aug 28.
Article in English | MEDLINE | ID: mdl-36157932

ABSTRACT

Hepatocellular carcinoma (HCC) is the sixth most common cancer. The main risk factors associated with HCC development include hepatitis B virus, hepatitis C virus, alcohol consumption, aflatoxin B1, and nonalcoholic fatty liver disease. However, hepatocarcinogenesis is a complex multistep process. Various factors lead to hepatocyte malignant transformation and HCC development. Diagnosis and surveillance of HCC can be made with the use of liver ultrasound (US) every 6 mo. However, the sensitivity of this imaging method to detect HCC in a cirrhotic liver is limited, due to the abnormal liver parenchyma. Computed tomography (CT) and magnetic resonance imaging (MRI) are considered to be most useful tools for at-risk patients or patients with inadequate US. Liver biopsy is still used for diagnosis and prognosis of HCC in specific nodules that cannot be definitely characterized as HCC by imaging. Recently the American College of Radiology designed the Liver Imaging Reporting and Data System (LI-RADS), which is a comprehensive system for standardized interpretation of CT and MRI liver examinations that was first proposed in 2011. In 2018, it was integrated into the American Association for the Study of Liver Diseases guidance statement for HCC. LI-RADS is designed to ensure high sensitivity, precise categorization, and high positive predictive value for the diagnosis of HCC and is applied to "high-risk populations" according to specific criteria. Most importantly LI-RADS criteria achieved international collaboration and consensus among liver experts around the world on the best practices for caring for patients with or at risk for HCC.


Subject(s)
Carcinoma, Hepatocellular , Liver Neoplasms , Aflatoxin B1 , Carcinoma, Hepatocellular/pathology , Contrast Media , Humans , Liver Neoplasms/pathology , Magnetic Resonance Imaging , Retrospective Studies , Sensitivity and Specificity
2.
Clin Case Rep ; 6(2): 450-451, 2018 02.
Article in English | MEDLINE | ID: mdl-29445499

ABSTRACT

A 43-year-old woman arrived to emergency unit of our hospital, referring intense deteriorated pain and swelling of midfoot. Rapid clinical evolvement of osteoarticular tuberculosis represents a potential clinical scenario. Clinicians should always include foot tuberculosis in differential diagnosis, in cases of severe clinical and radiological manifestations.

3.
EuroIntervention ; 12(8): e972-e978, 2016 Oct 10.
Article in English | MEDLINE | ID: mdl-27721213

ABSTRACT

AIMS: The purpose of this study was to assess the incidence and predictors of graft failure prior to discharge. Multi-slice computed tomography has the ability to evaluate graft patency in a non-invasive way. METHODS AND RESULTS: Of 145 consecutive patients who were screened, 73 were included in the study (78% male, mean age 65 years). A total of 206 grafts were analysed (2.8±0.9 grafts/patient). Of the 206 grafts, 126 were venous, 72 were left internal mammary, five were right internal mammary and three were radial grafts. We evaluated 100% of proximal anastomoses sites and 92% (190/206) of the distal anastomoses. We identified five patients (6.8%) who had at least one occluded graft. A total of seven out of 206 (3.4%) grafts were occluded. Independent predictors of successful graft outcome were left anterior descending artery as a recipient artery, good distal run-off as assessed by a surgeon and vessel size larger than 2 mm. CONCLUSIONS: The results demonstrate that the in-hospital acute graft failure rate is 3.4% (6.8% of patients). Multi-slice computed tomography is a robust technique to assess novel therapies to reduce the rate of graft attrition further, and might be clinically useful in patients with persistent or early recurrence of symptoms after CABG.


Subject(s)
Coronary Artery Bypass , Coronary Artery Disease/surgery , Graft Occlusion, Vascular/epidemiology , Postoperative Complications/epidemiology , Aged , Female , Graft Occlusion, Vascular/diagnostic imaging , Humans , Male , Mammary Arteries/transplantation , Middle Aged , Multidetector Computed Tomography , Postoperative Complications/diagnostic imaging , Prospective Studies , Radial Artery/transplantation , Saphenous Vein/transplantation , Treatment Outcome
4.
BMJ Case Rep ; 20132013 Sep 19.
Article in English | MEDLINE | ID: mdl-24051144

ABSTRACT

Brain irradiation has several well-known long-term side effects, including radiation-induced neoplasms and vasculopathy. In this case report, we describe an extremely rare case of meningioma and 15 cavernomas developing in a 29-year-old man, 19 years after cranial irradiation for posterior cranial fossa medulloblastoma. To our knowledge, this is the first case of a radiation-induced meningioma accompanied by this many radiation-induced cavernous angiomas.


Subject(s)
Cerebellar Neoplasms/radiotherapy , Hemangioma, Cavernous, Central Nervous System/etiology , Medulloblastoma/radiotherapy , Meningeal Neoplasms/etiology , Meningioma/etiology , Neoplasms, Radiation-Induced/diagnosis , Adult , Cerebellar Neoplasms/surgery , Diagnosis, Differential , Follow-Up Studies , Hemangioma, Cavernous, Central Nervous System/diagnosis , Hemangioma, Cavernous, Central Nervous System/surgery , Humans , Magnetic Resonance Imaging , Male , Medulloblastoma/surgery , Meningeal Neoplasms/diagnosis , Meningeal Neoplasms/surgery , Meningioma/diagnosis , Meningioma/surgery , Neoplasms, Radiation-Induced/surgery , Neurosurgical Procedures
5.
J Med Case Rep ; 4: 120, 2010 Apr 28.
Article in English | MEDLINE | ID: mdl-20426844

ABSTRACT

INTRODUCTION: Pseudo-Meigs' syndrome is a rare pathological entity characterized by the presence of a pelvic mass other than an ovarian fibroma. The mass is associated with ascites with or without hydrothorax. CASE PRESENTATION: We describe the case of a 41-year-old Caucasian woman with a large uterine leiomyoma associated with massive ascites. A magnetic resonance imaging scan showed a large subserosal leiomyoma with multiple areas of cystic degeneration. CONCLUSION: To the best of our knowledge, this is the first reported case of pseudo-Meigs' syndrome caused by a uterine leiomyoma and diagnosed using magnetic resonance imaging. The pathophysiology of this syndrome and the role of magnetic resonance imaging are emphasized in this case report.

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