Subject(s)
Carotid Artery, Internal, Dissection/complications , Clonidine/analogs & derivatives , Horner Syndrome/diagnosis , Miosis/diagnosis , Adrenergic alpha-1 Receptor Agonists , Adrenergic alpha-Agonists/administration & dosage , Adult , Carotid Artery, Internal/diagnostic imaging , Carotid Artery, Internal/pathology , Carotid Artery, Internal, Dissection/diagnostic imaging , Carotid Artery, Internal, Dissection/pathology , Cerebral Angiography , Clonidine/administration & dosage , Diagnosis, Differential , Horner Syndrome/etiology , Horner Syndrome/physiopathology , Humans , Iris/drug effects , Iris/innervation , Iris/physiopathology , Male , Miosis/etiology , Miosis/physiopathology , Predictive Value of Tests , Receptors, Adrenergic, alpha-1/physiology , Sympathetic Fibers, Postganglionic/drug effects , Sympathetic Fibers, Postganglionic/injuries , Sympathetic Fibers, Postganglionic/physiopathology , Time Factors , Tomography, X-Ray Computed , Up-Regulation/drug effects , Up-Regulation/physiologyABSTRACT
We report 2 cases in which an Artisan phakic intraocular lens (IOL) (Ophtec) was used to successfully treat high myopia after penetrating keratoplasty (PKP). The first case was a 43-year-old man who had a manifest refraction of -13.75 +3.00 x 50 with a best corrected visual acuity (BCVA) of 20/40(-2) after PKP in the left eye. Approximately 9 months after implantation of the Artisan IOL, the manifest refraction was -2.00 +2.50 x 60 with a BCVA of 20/30(+2). The second case was a 31-year-old man who had a manifest refraction of -10.75 +2.25 x 122 and a BCVA of 20/40 after corneal transplantation in the right eye. Ten months after implantation of the Artisan IOL, the manifest refraction was -2.75 +4.75 x 80 with a BCVA of 20/40. Endothelial cell density did not change significantly in either patient after surgery. The Artisan phakic IOL may provide an alternative method to correct high myopia after PKP.