ABSTRACT
The purpose of the present investigation was to enhance the efficiency of diagnosis of thyroid diseases in irradiated persons. Three hundred persons exposed to radiation in doses of 5 to 250 SeV and the postexposure period was 9 to 48 years. A control group comprised 100 military men unexposed to ionizing radiation. Thyroid ultrasound study and morphological diagnosis revealed diffuse nodular goiter transformation in 66% of the irradiated persons and malignant thyroid neoplasms in 3.7% whereas 38% of the control patients were found to have only benign diffuse nodular thyroid alterations and autoimmune thyroiditis (AIT). The investigation identified the echosemiotic features of nodular masses and AIT in the study group patients and established their association with the pathomorphological changes of the thyroid. The authors note the high efficiency of complex clinicoradiation and morphological studies in detecting thyroid pathology and the priority in establishing an accurate diagnosis at the preoperative stage and in determining management tactics.
Subject(s)
Radiation Injuries/complications , Thyroid Neoplasms/diagnostic imaging , Thyroid Neoplasms/etiology , Chernobyl Nuclear Accident , Diagnosis, Differential , Female , Humans , Male , Middle Aged , Severity of Illness Index , Thyroid Neoplasms/pathology , UltrasonographyABSTRACT
Complex cytological and ultrasound study was conducted in 300 patients with thyroid pathology exposed to 5-250 cSv. Benign goiter changes and autoimmune thyroiditis were detected in 66.2% while malignant thyroidal nodules--in 3.7%. Benign and autoimmune changes alone were in 38%. Pathomorphological features of nodular changes and autoimmune thyroiditis patterns as well as their ultrasound representations were identified.