ABSTRACT
We hypothesized that fetal exposure to the oxidative stress induced by the combined challenge of preeclampsia (PE) and high altitude would induce a significant impairment in the development of pulmonary circulation. We conducted a prospective study in La Paz (Bolivia, mean altitude 3625 m) in which newborns from singleton pregnancies with and without PE were compared (PE group n = 69, control n = 70). We conducted an echocardiographic study in these infants at the median age of two days. The percentage of cesarean deliveries and small for gestational age (SGA) infants was significantly higher in the PE group. Heart rate, respiratory rate, and oxygen saturation did not vary significantly between groups. Estimated pulmonary arterial pressure and pulmonary vascular resistance were 30% higher in newborns exposed to PE and high altitude compared with those exposed only to high altitude. We also detected signs of right ventricular hypertrophy in infants subjected to both exposures. In conclusion, this study provides evidence that the combination of PE and pregnancy at high altitude induces subclinical alterations in the pulmonary circulation of the newborn. Follow-up of this cohort may provide us with valuable information on the potential increased susceptibility to developing pulmonary hypertension or other pulmonary and cardiovascular disorders.
ABSTRACT
El objetivo del presente trabajo es el de proporcionar un documento que sirva de base para especificar los equipos de control de posición de las diferentes bahías en una subestación típica de distribución en el sistema electropaz. En este documento se mostrará la especificación de los equipos del SIPCO en su Hardware y sofware.Las posiciones que se desarrollan son:Control de los interruptores de líneas de transmisión de alta tensión.Control del interruptor de alta tensión de un transformador.Control de interruptor de media tensión de un transformador.Control de los interruptores de los alimentadores.