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Binding Differences of Two Homochiral [Ru(bpy)₂dppz]²⁺ Complexes with poly(U)·poly(A)*poly(U) Triplex RNA.

Peng, Meng-Na; Zhu, Zhi-Yuan; Tan, Li-Feng.

Inorg Chem ; 56(13): 7312-7315, 2017 Jul 03.

Article in English | MEDLINE | ID: mdl-28636339

ABSTRACT

The first investigation of chiral ruthenium(II) complexes Δ- and Λ-[Ru(bpy)2dppz]2+ and triplex RNA poly(U)·poly(A)*poly(U) was carried out, which showed that Δ enantiomer displayed significant ability in stabilizing model triplex RNA.

Subject(s)

Organometallic Compounds/chemistry , Poly A/chemistry , Poly U/chemistry , RNA/chemistry , Ruthenium/chemistry , Binding Sites , Molecular Conformation

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