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1.
Sci Rep ; 9(1): 19905, 2019 Dec 20.
Article in English | MEDLINE | ID: mdl-31857668

ABSTRACT

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

2.
Sci Rep ; 9(1): 8053, 2019 May 29.
Article in English | MEDLINE | ID: mdl-31142790

ABSTRACT

We report on measurements of the switching current distributions on two-dimensional superconducting NbTiN strips that are 5 nm thick and 80 nm wide. We observe that the width of the switching current distributions has a non-monotonous temperature dependence, where it is constant at the lowest temperatures up to about 1.5 K, after which it increases with temperature until 2.2 K. Above 2.5 K any increase in temperature decreases the distribution width which at 4.0 K is smaller than half the width observed at 0.3 K. By using a careful analysis of the higher order moments of the switching distribution, we show that this temperature dependence is caused by switching due to multiple fluctuations. We also find that the onset of switching by multiple events causes the current dependence of the switching rate to develop a characteristic deviation from a pure exponential increase, that becomes more pronounced at higher temperatures, due to the inclusion of higher order terms.

3.
Reprod Biomed Online ; 5(2): 104-8, 2002.
Article in English | MEDLINE | ID: mdl-12419032

ABSTRACT

The aim of this study was to evaluate the use of recombinant luteinizing hormone (rLH) supplementation in an unselected group of IVF patients undergoing follicular stimulation with recombinant follicle stimulating hormone (rFSH) after pituitary down-regulation. Group A comprised 122 cycles administered rFSH and rLH while group B included 331 cycles using rFSH only during the same period of treatment. There was no significant difference in any of the endocrine, embryological and outcome parameters measured. The implantation rate of 14.2% for group A compared with 9.8% for group B showed a positive trend (P = 0.055), but for patients in whom LH concentration was <1.0 IU/l at down-regulation or required excessive FSH stimulation, there was an increased incidence of implantation if rLH was supplemented. It was concluded that the addition of exogenous rLH to an unselected group of 'down-regulated' patients stimulated with rFSH appears to offer little benefit, but in the event of profound LH down-regulation or requirement for excessive exogenous FSH (>2500 IU), the rate of implantation might be improved.


Subject(s)
Embryo Implantation/physiology , Fertilization in Vitro , Follicle Stimulating Hormone/therapeutic use , Luteinizing Hormone/therapeutic use , Ovulation Induction/methods , Recombinant Proteins/therapeutic use , Adult , Delivery, Obstetric , Drug Therapy, Combination , Embryo Implantation/drug effects , Estradiol/blood , Female , Fertilization in Vitro/methods , Follicle Stimulating Hormone/blood , Humans , Infant, Newborn , Luteinizing Hormone/blood , Pregnancy , Pregnancy Outcome , Prolactin/blood
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