ABSTRACT
Tetradenia riparia (Hochst.) Codd (Lamiaceae) is a shrub, commonly known as ginger bush or false myrrh, and several studies have shown that T. riparia exhibits a variety of biological properties. This study aimed to determine the chemical composition of T. riparia essential oil and its fractions, investigate their anticholinesterase activity, and assess their larvicidal activity against the cattle tick Rhipicephalus microplus and the mosquito Aedes aegypti. Eleven essential oil fractions were obtained by fractionation and analyzed by gas chromatography/mass spectrometry. Larvicidal activity against R. microplus and third-instar A. aegypti was assessed using a larval packet test and a larval immersion test, respectively. Anticholinesterase activity was determined by a bioautographic method. Forty-nine compounds were identified in the essential oil, of which the major classes were oxygenated sesquiterpenes (45.95%) and sesquiterpene hydrocarbons (35.20%) and the major components were isospathulenol (17.40%), ß-caryophyllene (15.61%), 14-hydroxy-9-epi-caryophyllene (10.07%), 14-hydroxy-α-muurolene (8.32%), and 9ß,13ß-epoxy-7-abietene (5.53%). Bioassays showed that T. riparia essential oil (LC50 = 1.56 µg/mL) and FR3 (LC50 = 0.30 µg/mL) were the most active against R. microplus and A. aegypti larvae, respectively. The essential oil and FR1, FR2, and FR3 exhibited acetylcholinesterase inhibitory activity. These results indicate that T. riparia essential oil and its fractions hold promise in the development of novel, environmentally safe agents for the control of R. microplus and A. aegypti larvae.
Subject(s)
Ticks , Aedes , Lamiaceae/toxicity , Lamiaceae/chemistry , LarvicidesABSTRACT
O objetivo deste estudo foi avaliar o conhecimento sobre plantas medicinais e medicamentos fitoterápicos em uma instituição de ensino superior da Região Sul do Brasil a Universidade Paranaense -UNIPAR, considerando a importância da fitoterapia para a formação profissional dos cursos de Farmácia. Foi desenvolvido, um estudo quantitativo e descritivo, aplicando um questionário, pelo Google Formulários, para avaliar o conhecimento sobre as plantas e fitoterápicos, com todos os 23 acadêmicos do 4ºano do curso de farmácia. Os resultados demonstraram que 60,9% dos alunos faz uso de alguma planta medicinal, 95,7% dos acadêmicos aprendeu utilizar plantas medicinais na faculdade e as plantas mais citadas foram: hortelã, hibisco e boldo, 95,7% respondeu que indicaria uso de fitoterápicos e plantas medicinais para outras pessoas, 87% dos acadêmicos responderam que talvez faça uma especialização em plantas medicinais e fitoterápicos. Este estudo demonstra que os acadêmicos, utilizam plantas medicinais com certa frequência, adquiriram informações provenientes da Universidade e do saber tradicional adquirido, havendo a necessidade de maior conhecimento sobre a importância do aperfeiçoamento profissional, com a realização de especialização, considerando o potencial da fitoterapia(AU)
The aim of this study was to evaluate the knowledge about medicinal plants and herbal medicines in a higher education institution in the southern region of Brazil, Universidade Paranaense -UNIPAR, considering the importance of herbal medicine for the professional training of pharmacy courses. A quantitative and descriptive study was developed, applying a questionnaire, by Google Forms, to assess the knowledge about plants and herbal medicines, with all 23 academics from the 4th year of the pharmacy course.The results showed that 60.9% of students use some medicinal plant, 95.7% of students learned to use medicinal plants in college and the most cited plants were: mint, hibiscus and boldo, 95.7% answered that they would indicateuse from herbal medicines and medicinal plants to other people, 87% of academics responded that perhaps they do a specialization in medicinal plants and herbal medicines. This study demonstrates that academics, using medicinal plants with a certain frequency, acquired information from the University and acquired traditional knowledge, with the need for greater knowledge about the importance of professional improvement, with the realization of specialization, considering the potentialof herbal medicine(AU)
El objetivo de este estudio fue evaluar el conocimiento sobre plantas medicinales y medicinas a base de hierbas en una institución de educación superior en la región sur de Brasil, la Universidade Paranaense -UNIPAR, considerando la importancia de la fitoterapia para la formación profesional de los cursos de farmacia. Se desarrolló un estudio cuantitativo y descriptivo, aplicando un cuestionario, de Google Forms, para evaluar los conocimientos sobre plantas y medicinas a base de hierbas, con los 23 académicos del 4º año del curso de farmacia. Los resultados mostraron que el 60.9% de los estudiantes usa alguna planta medicinal, el 95.7% de los estudiantes aprendió a usar plantas medicinales en la universidad y las plantas más citadas fueron: menta, hibisco y boldo, el 95.7% respondió que indicaría uso de hierbas medicinales y medicinales. plantas a otras personas, el 87% de los académicos respondió que tal vez hacen una especialización en plantas medicinales y medicinas a base de hierbas. Este estudio demuestra que los académicos, utilizando plantas medicinales con cierta frecuencia,adquirieron información de la Universidad y adquirieron conocimientos tradicionales, con la necesidad de un mayor conocimiento sobre la importancia de la superación profesional, con la realización de la especialización, considerando el potencial de la fitoterapia(AU)
