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Adverse events and humoral response after two doses of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) mRNA vaccine in the hospital personnel of a cardiopulmonary tertiary-care center.

De Vita, Erica; Sbrana, Francesco; Quattrone, Filippo; Dal Pino, Beatrice; Megaro, Monica; Lombardi, Roberta; Prontera, Concetta; Passino, Claudio; Petrillo, Maurizio.

Infect Control Hosp Epidemiol ; 43(10): 1532-1534, 2022 10.

Article in English | MEDLINE | ID: mdl-34261574

Subject(s)

COVID-19 , SARS-CoV-2 , Humans , Antibodies, Viral , COVID-19/prevention & control , Personnel, Hospital , Vaccines, Synthetic , COVID-19 Vaccines , mRNA Vaccines

Prolonged outbreak of New Delhi metallo-beta-lactamase-producing carbapenem-resistant Enterobacterales (NDM-CRE), Tuscany, Italy, 2018 to 2019.

Tavoschi, Lara; Forni, Silvia; Porretta, Andrea; Righi, Lorenzo; Pieralli, Filippo; Menichetti, Francesco; Falcone, Marco; Gemignani, Giulia; Sani, Spartaco; Vivani, Paola; Bellandi, Tommaso; Tacconi, Danilo; Turini, Lucia; Toccafondi, Giulio; Privitera, Gaetano; Lopalco, Pierluigi; Baggiani, Angelo; Gemmi, Fabrizio; Luchini, Grazia; Petrillo, Maurizio; Roti, Lorenzo; Pezzotti, Patrizio; Pantosti, Annalisa; Iannazzo, Stefania; Mechi, Maria Teresa; Rossolini, Gian Maria.

Euro Surveill ; 25(6)2020 02.

Article in English | MEDLINE | ID: mdl-32070467

ABSTRACT

In Tuscany, Italy, New Delhi metallo-beta-lactamase-producing carbapenem-resistant Enterobacterales (NDM-CRE) have increased since November 2018. Between November 2018 and October 2019, 1,645 samples were NDM-CRE-positive: 1,270 (77.2%) cases of intestinal carriage, 129 (7.8%) bloodstream infections and 246 (14.9%) infections/colonisations at other sites. Klebsiella pneumoniae were prevalent (1,495; 90.9%), with ST147/NDM-1 the dominant clone. Delayed outbreak identification and response resulted in sustained NDM-CRE transmission in the North-West area of Tuscany, but successfully contained spread within the region.

Subject(s)

Anti-Bacterial Agents/pharmacology , Carbapenems/pharmacology , Disease Outbreaks , Klebsiella Infections/epidemiology , Klebsiella Infections/microbiology , Klebsiella pneumoniae/drug effects , beta-Lactamases/metabolism , Adolescent , Adult , Aged , Aged, 80 and over , Child , Child, Preschool , Drug Resistance, Multiple, Bacterial/drug effects , Female , Humans , Infant , Infant, Newborn , Italy/epidemiology , Klebsiella Infections/drug therapy , Klebsiella pneumoniae/enzymology , Klebsiella pneumoniae/metabolism , Male , Microbial Sensitivity Tests , Middle Aged , Young Adult , beta-Lactamases/drug effects , beta-Lactamases/genetics

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