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2.
Eksp Klin Gastroenterol ; (1): 47-50, 2011.
Article in Russian | MEDLINE | ID: mdl-21560389

ABSTRACT

The results of investigation of 87 children suffering from chronic gastroduodenitis and atopic dermatitis are presented. All the child underwent fibrogastroduodenoscopy with duodenal mucosal biopsy and diagnostics of Helicobacter pylori infection, lambliasis. Hystomorphological and immunohystochemical studies of mucosal biopsy specimens for Epstein - Barr virus were carried out. The role of atopy and infection factors in genesis of chronic gastroduodenitis was evaluated.


Subject(s)
Dermatitis, Atopic/pathology , Duodenitis/pathology , Duodenum/pathology , Epstein-Barr Virus Infections/pathology , Helicobacter Infections/pathology , Helicobacter pylori , Herpesvirus 4, Human , Intestinal Mucosa/pathology , Adolescent , Biopsy , Child , Chronic Disease , Dermatitis, Atopic/complications , Dermatitis, Atopic/metabolism , Duodenitis/complications , Duodenitis/metabolism , Duodenitis/virology , Duodenum/metabolism , Duodenum/virology , Endoscopy, Digestive System/methods , Epstein-Barr Virus Infections/metabolism , Female , Helicobacter Infections/metabolism , Humans , Intestinal Mucosa/metabolism , Intestinal Mucosa/virology , Male
3.
Eksp Klin Gastroenterol ; (1): 37-40, 2010.
Article in Russian | MEDLINE | ID: mdl-20405709

ABSTRACT

The results of investigation of 49 children suffering from chronic gastroduodenitis and atopic dermatitis are presented. All the child underwent serological blood analyses for Epsteine-Barr virus antibodies and fibrogastroduodenoscopy with antral and duodenal mucosal biopsy. Hystomorphological and immunohystochemical studies of mucosal biopsy specimens for Epsteine-Barr virus were carried out. The role of Epsteine-Barr virus in genesis of chronic gastroduodenitis is detected.


Subject(s)
Dermatitis, Atopic/complications , Duodenitis/pathology , Duodenitis/virology , Epstein-Barr Virus Infections/complications , Gastritis/pathology , Gastritis/virology , Adolescent , Antibodies, Viral/blood , Antigens, Viral/isolation & purification , Child , Chronic Disease , Duodenitis/complications , Gastric Mucosa/immunology , Gastric Mucosa/pathology , Gastritis/complications , Herpesvirus 4, Human/immunology , Herpesvirus 4, Human/isolation & purification , Humans , Pyloric Antrum/pathology
4.
Arkh Patol ; 72(1): 33-5, 2010.
Article in Russian | MEDLINE | ID: mdl-20369583

ABSTRACT

Gastric mucosal biopsy specimens were immunohistochemically studied to detect the antigens of herpes simplex virus, cytomegalovirus, and Epstein-Barr virus (EB ) in 103 children aged 7-17 years and 49 adults aged 18-78 years who suffered from morphologically verified chronic gastritis. Gastric mucosal virus antigens were found in 70% of the children (including EBV in 44.8%; herpes simplex virus in 34.9%, cytomegalovirus in 16.5%; concurrence of two and three infections in 22.3 and 1.9%, respectively) and in 65.3% of the adults (EBV in 408%; herpes simplex virus in 26.5%, cytomegalovirus in 18.4%; concurrence of two and three infections in 26.3 and 2%, respectively). It was shown that herpes viruses may play an etiological role in the development of chronic gastritis in children and adults.


Subject(s)
Antigens, Viral/biosynthesis , Gastric Mucosa , Gastritis , Herpesviridae Infections , Adolescent , Adult , Age Factors , Aged , Child , Female , Gastric Mucosa/metabolism , Gastric Mucosa/physiology , Gastric Mucosa/virology , Gastritis/etiology , Gastritis/metabolism , Gastritis/pathology , Gastritis/virology , Herpesviridae Infections/complications , Herpesviridae Infections/metabolism , Herpesviridae Infections/pathology , Humans , Male , Middle Aged
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