1.
Chemistry
; 19(35): 11547-52, 2013 Aug 26.
Article
in English
| MEDLINE
| ID: mdl-23893767
ABSTRACT
Bump the base: This study reports the discovery of the base-induced Z-to-E isomerization of exo-glycals bearing an electron-withdrawing group (EWG). The scope of this novel transformation regarding the carbohydrate unit is also discussed. After elucidating the mechanism, preparation of novel (E)-exo- glycals was performed (TBS = tert-butyldimethylsilyl).