ABSTRACT
Thiamine deficiency resulted in inhibition of two main pathways supplying energy to the tissues: glycolysis and ß-oxidation. Glycolysis was found to be inhibited to 40% of initial value calculated on the basis of RBC trans-membrane transport of glucose. Prolongation of experiment cause lowering of uptake of this sugar. In rats, energy production from fatty acids (FA) seems to be less sensitive to thiamine deficiency than glycolysis. After 30 days of feeding, utilization of FA in rats was depressed to the 61% of initial value. Thiamine deficiency suppressed insulin secretion, and the changes were statistically significant. Feeding of rats with thiamine restricted diet for 1 month caused the reduction of serum insulin by 14%. In the same animals, trans-membrane glucose transport was reduced over two-times, what might suggest a decreased efficiency of insulin action in such conditions. The kind and concentration of non-digestible fructo-oligosaccharides (FOS) did not affect significantly serum insulin concentration in animals fed thiamine restricted diet. Substitution of a part of wheat starch with FOS has only insignificant compensatory effect on the uptake of glucose. A partial amelioration of the ß-oxidation inhibition caused by feeding rats with thiamine deficient diet was observed in animals supplemented with FOS. However, this effect was statistically significant only in rats receiving diet containing 10% of inulin. The effect of supplemented FOS and their concentration on trans-membrane glucose transport in RBC was statistically significant, when pulled supplementation groups were used for statistical evaluation.
Subject(s)
Dietary Supplements , Inulin/therapeutic use , Oligosaccharides/therapeutic use , Thiamine Deficiency/drug therapy , Animal Feed/analysis , Animals , Diet , Glucose/metabolism , RatsSubject(s)
Aflatoxin B1/toxicity , Carcinogens/toxicity , Mutagens/toxicity , Aflatoxin B1/antagonists & inhibitors , Aflatoxin B1/chemistry , Animals , Antimutagenic Agents/pharmacology , Aspergillus flavus/metabolism , Biotransformation , Carcinogens/chemistry , Cytochrome P-450 Enzyme System/metabolism , Tumor Suppressor Protein p53/geneticsABSTRACT
The aim of the study was evaluation if nutrition education effect on food consumption in students. The group of 110 students, 50% from Faculty of Human Nutrition & Home Economics and other from Horticulture Faculty was investigated. Food consumption quality was estimated using 24 hours recall method and modified by Kulesza test of Bielinska. It has been shown, that nutrition education did not significantly effect on food consumption of students.
Subject(s)
Health Behavior , Health Education , Health Promotion , Nutritional Physiological Phenomena , Students/psychology , Adult , Diet , Energy Intake , Female , Humans , Male , PolandABSTRACT
The availability of beta-carotene was studied from carrots and sorrel grown by conventional and ecological methods. The vegetables were bought in the market and in a shop with ecological food, and they had Ekoland atests. The bioavailability was determined by the hepatic test. No significant effect of growing method of the studied vegetables on beta-carotene bioavailability was found.