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Folia Med (Plovdiv) ; 64(4): 676-681, 2022 Aug 31.
Article in English | MEDLINE | ID: mdl-36045471

ABSTRACT

Reparative giant cell granulomas are benign masses of multi-etiological nature, which account for 1%-7% of all benign lesions of the jaws. The objective of this case report is to present the relationship between isolated vitamin D deficiency and the development of reparative giant cell granuloma.Herein, we present the case of a 70-year-old female patient with a painless mass of increased mobility in the mandibular region, and pain in the involved teeth. After histological confirmation and laboratory screening, а reparative giant cell granuloma caused by serious deficiency of vitamin D3 - (25-OH)D was diagnosed. The treatment protocol included surgical removal of the lesion and vitamin D replacement therapy.In rare cases, this type of lesion can be a primary manifestation of vitamin D deficiency; therefore, it is extremely important to be aware of this pathology.


Subject(s)
Giant Cell Tumors , Granuloma, Giant Cell , Vitamin D Deficiency , Aged , Cholecalciferol/therapeutic use , Female , Granuloma, Giant Cell/diagnosis , Granuloma, Giant Cell/etiology , Granuloma, Giant Cell/surgery , Humans , Vitamin D , Vitamin D Deficiency/complications
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