ABSTRACT
BACKGROUND AND AIM: Gonorrhea is a bacterial infection in the urogenital tract, transmitted by sexual or perinatal contact, caused by Neisseria gonorrhoeae, a gram-negative diplococcus. The present study evaluates the frequency of N. gonorrhoeae in women treated at Hospital Wladimir Arruda in poor area of São Paulo and also verifies the presence of genetic resistance against three antimicrobials of different classes: Tetracycline, Azithromycin and Ciprofloxacin. METHODS: This is an observational and descriptive study with a quantitative approach. Samples were collected at Hospital Escola Wladimir Arruda. The volunteers are women from 16 to 65 years of age. Sociodemographic, gynecological, sexual and health data are collected through a questionnaire, their symptoms/clinical manifestation were requested by the medical records, and then the participant is referred for collection of samples of cervical vaginal smear. The samples were screened for N. gonorrhoeae (dcmH gene) and tested for resistance genes to Tetracycline, Azithromycin and Ciprofloxacin through PCR. RESULTS: In the total of 127 samples analyzed by Real-Time PCR, 23 were positive and correspond to a general prevalence of a gonococcal infection in the studied population of 17% (CI:95%), and the participants were married (43.4%), had active sexual life (56.5%) and did not use any type of condom during sexual intercourse (52.1%). The resistance to the tetM ribosomal gene was found in 14 samples, prevalence of 60% (CI= 95%). CONCLUSIONS: We have described a concerning frequency of N. gonorrhoeae infection in females attended in an outcare patient. Also, most of the strains detected presented resistance to one or more antimicrobials.
Subject(s)
Anti-Infective Agents , Gonorrhea , Humans , Female , Gonorrhea/epidemiology , Gonorrhea/drug therapy , Gonorrhea/microbiology , Azithromycin/therapeutic use , Brazil/epidemiology , Microbial Sensitivity Tests , Anti-Bacterial Agents/pharmacology , Anti-Bacterial Agents/therapeutic use , Neisseria gonorrhoeae/genetics , Ciprofloxacin/therapeutic use , Tetracycline , Anti-Infective Agents/therapeutic useABSTRACT
Abstract Aims: The purpose of this study is to assess the prevalence of oral and dentoalveolar trauma among contact sports practitioners in the Federal District of Brazil. Methods: A cross-sectional descriptive study was conducted using a questionnaire developed specifically for this research regarding the occurrence of facial trauma, site of injuries, how they occurred, the approach is taken to solve the problem, and the use of several types of mouthguards. Data were analyzed using the SPSS 20.0 software, and the chi-square test (X2) was chosen to examine the differences between categorical variables. The results were considered statistically significant for p<0.05. Results: A total of 141 athletes were interviewed, with a prevalence of facial trauma of 65.2%, which was higher in professional athletes (71.1%). Lesions ranged from soft tissue lacerations to combined trauma; and the most frequent injuries were soft tissue laceration (53.3%), combined trauma (16.3%), and dental fracture (9.8%). Only 20.6% of the participants required treatment for related injuries. Regarding the use of mouthguards, 34% of the athletes reported regular use of this device, and Type II mouthguard was the most used (39.7%). Dentists participate in the process of production and dissemination of mouthguards in 17.1% and 10.5% of cases, respectively. Conclusion: The data showed that most athletes are not aware of the importance of using mouthguards. The dentist must be more present in the area of sports dentistry, both for awareness and production of these devices, which support the safe practice of contact sports.