Subject(s)
Drainage/methods , Lung Injury/etiology , Pneumothorax/etiology , Subcutaneous Emphysema/surgery , Aged , Biopsy/adverse effects , Carcinoma, Bronchogenic/pathology , Catheterization , Drainage/instrumentation , Humans , Lung/pathology , Lung Neoplasms/pathology , Male , Recurrence , Subcutaneous Emphysema/etiologyABSTRACT
La fiebre Q es una zoonosis de distribución universal producida por Coxiella burnetti. La forma aguda de esta infección casi siempre produce afectación pulmonar y hepática en forma de neumonía y hepatitis a través del efecto directo de C. burnetti sobre los órganos afectados. Se describe en este trabajo la presencia de una hepatitis autoinmune y anticuerpos antifosfolípido como una complicación transitoria de esta infección. Estas manifestaciones son probablemente más frecuentes de lo que pensamos y probablemente estén infradiagnosticadas, por lo que consideramos que esta aportación clínica es importante para un conocimiento más profundo acerca de la fiebre Q y sus complicaciones (AU)
Q fever is a worldwide infection caused by Coxiella burnetti. The acute form of this condition usually produces pneumonia and hepatitis through the direct effect of Coxiella burnettion the involved organs. Here we describe the presence of autoimmune hepatitis and antiphospholipid antibodies as a transitory complication of this infection. These manifestations are probably more frequent than thought and they maybe underdiagnosed; so this report could be important for a deeper knowledge about Q fever and its complications (AU)
Subject(s)
Humans , Q Fever/complications , Antibodies, Antiphospholipid/immunology , Hepatitis, Autoimmune/etiology , Q Fever/immunology , Coxiella burnetii/pathogenicity , Coxiella burnetii/immunology , Lupus Coagulation InhibitorABSTRACT
La ascariasis es la parasitosis más frecuente de todas las helmintiasis en humanos. Los efectos patológicosproducidos por los áscaris en el hombre se presentan en lugares diversos, de acuerdo con la localizaciónde sus distintas formas evolutivas. La ascariasis biliar en una de las complicaciones más severas.Presentamos un caso de pancreatitis aguda producida por infestación por Áscaris
Ascariasis is the commonest parasitosis of all human helminths. The pathological effects that ascaris producesin man manifest in different locations, in accordance with the location of its different evolutionaryforms. Biliary ascaris is one of the severest complications. We present a case of acute pancreatitis produced by Ascaris infestation
Subject(s)
Humans , Male , Adult , Pancreatitis, Acute Necrotizing/parasitology , Ascaris lumbricoides/pathogenicity , Ascaridiasis/complicationsABSTRACT
La nocardiosis es una enfermedad invasiva producida por especies del género Nocardia, bien a travésde la inhalación o la inoculación cutánea. Se presentan dos casos de neumonía por Nocardia en pacientes inmunodeprimidos
Nocardiosis is an invasive disease caused by the Norcardia species, either through inhalation orcutaneous inoculation. We report two cases of pneumonia caused by Norcadia in immunodepressed patients
Subject(s)
Humans , Male , Adult , Aged , Nocardia Infections/complications , Pneumonia/microbiology , Nocardia/pathogenicity , Immunocompromised Host , AIDS-Related Opportunistic Infections/microbiology , Pulmonary Disease, Chronic Obstructive/complicationsSubject(s)
Deferoxamine/administration & dosage , Hemochromatosis/drug therapy , Adult , Amino Acid Substitution , Female , Ferritins/blood , Hemochromatosis/blood , Hemochromatosis/genetics , Hemochromatosis Protein , Heterozygote , Histocompatibility Antigens Class I/genetics , Humans , Injections, Intramuscular , Iron/blood , Male , Membrane Proteins/genetics , Phlebotomy/adverse effects , Point MutationABSTRACT
Myoglobinuric acute renal failure has three pathogenic mechanisms: tubular obstruction, renal vasoconstriction, and oxidative stress. The latter is generated through the iron released from the group hemo of the myoglobin. Iron induces the formation of high-activity oxygen free radicals that increase oxidative stress and provoke lipid peroxidation and cellular death. This oxidative stress can be measured in several ways, both total or partially with the total antioxidant status or the intermediate enzymes. On the other hand, N-acetylcysteine is a demonstrated substance with antioxidant properties. The aim of the present work was to assess the effect of N-acetylcysteine on the oxidative stress in the glycerol-induced acute renal failure in rats model. We observed that the animals treated with N-acetylcysteine showed an improvement in the antioxidant activity given by an increase in the total antioxidant status and glutathione reductase levels in serum. This improvement was greater when treatment was administered before the induction of rhabdomyolysis. Nevertheless, the observed increase in antioxidant status was only statistically significant for glutathione reductase but not for total antioxidant status. Our results support an important role for N-acetylcysteine in the treatment of this form of acute renal failure, although we think that oxidative stress is not the main pathogenic mechanism of the tubular necrosis induced by rhabdomyolysis, tubular obstruction and renal vasoconstriction being still more important.
Subject(s)
Acetylcysteine/pharmacology , Acute Kidney Injury/drug therapy , Acute Kidney Injury/pathology , Oxidative Stress/drug effects , Analysis of Variance , Animals , Disease Models, Animal , Female , Glycerol , Kidney Function Tests , Male , Oxidative Stress/physiology , Probability , Random Allocation , Rats , Rats, Sprague-Dawley , Reference Values , Sensitivity and SpecificityABSTRACT
No disponible
Subject(s)
Middle Aged , Adult , Male , Female , Humans , Sentinel Lymph Node Biopsy , Biomarkers , Melanoma , ImmunohistochemistryABSTRACT
No disponible
Subject(s)
Middle Aged , Male , Female , Humans , Sarcoidosis , Ofloxacin , Anti-Infective Agents, Urinary , Sweet Syndrome , TendinopathyABSTRACT
No disponible