ABSTRACT
An output coupler comprising a resonant grating submirror monolithically associated with a standard multilayer submirror polarizes the emission of a Nd:YAG microchip laser linearly over its full emission bandwidth by intra-mirror destructive interference for the undesired polarization. A polarization extinction ratio of more than 25 dB is obtained up to 6.1microJ pulse energy. This passively Q-switched laser performance is almost identical to that of a gratingless non-polarized microchip laser. The design and fabrication of the resonant grating mirror are described.
ABSTRACT
We demonstrate the use of a High Reflectivity Grating (HRG) as an intra-cavity element in a Semiconductor Disk Laser (or Vertical External Cavity Surface Emitting Laser) to stabilise its emission wavelength and polarization characteristics. Operation at 1058nm with up to 645mW of pump-limited output power and an M(2)~1.4 is achieved. We also show that this scheme permits tunable single-frequency operation.
ABSTRACT
Antitumoral effects and intratumoral concentrations of a metalloporphyrin were studied in mice with solid chemo-induced or transplanted tumors. The synthesis of this molecule was realised both with a stable metal (TPPS4SnCl2) (TPPS4InCl) and a radioactive metal (TPPS4(113)SnCl2) (TPPS4(111)InCl). The metal is introduced into the tetrapyrollic structure to give this molecule very high stability. The effect of the stable metalloporphyrin on tumoral kinetic parameters was analyzed. No tumoral regression was observed during the various experimental procedures. Even though radioactive molecules were found in the tumours, they were also present as high concentrations in the liver, spleen and kidneys, more than 72 hours after injection. Results are compared with those of various authors who used a molecule without metal, levels being measured by fluorescence in various organs and in the tumors. The interest of this metalled molecule in carcinology is discussed in relation to these new results.
