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J Comp Pathol ; 128(1): 67-70, 2003 Jan.
Article in English | MEDLINE | ID: mdl-12531689

ABSTRACT

Two bilaterally deaf and three unilaterally deaf pups were identified from a litter of 10 Dogo Argentino pups presented for hearing evaluation by electrophysiological investigation. One pup, a bilaterally deaf female aged 43 days, was available for histopathology. Examination of both inner ears revealed bilateral cochlear degeneration with atrophy of the stria vascularis, collapse of the cochlear duct, degeneration of the organ of Corti, and abnormal tectorial membrane. The left vestibule, including the sacculus, was normal. The spiral and vestibular ganglia were essentially normal. This is the first histopathological description of lesions associated with deafness in a Dogo Argentino, but abnormalities were similar to those previously described in deaf Dalmatian pups and in other white hair-coated breeds. The defect was classified as a cochleosaccular degeneration. It was probably congenital and genetic causes were suspected.


Subject(s)
Cochlea/pathology , Cochlear Diseases/veterinary , Deafness/veterinary , Dog Diseases/pathology , Animals , Animals, Newborn , Cochlear Diseases/congenital , Cochlear Diseases/pathology , Deafness/congenital , Deafness/pathology , Deafness/physiopathology , Dogs , Euthanasia, Animal , Evoked Potentials, Auditory, Brain Stem/physiology , Female , Male
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