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1.
Eur Ann Otorhinolaryngol Head Neck Dis ; 139(5): 255-259, 2022 Oct.
Article in English | MEDLINE | ID: mdl-35581118

ABSTRACT

OBJECTIVE: The main objective of this pediatric study of otologic surgery was to analyze factors for success of outpatient management. The secondary objective was to study unscheduled postoperative consultations and readmissions. MATERIALS AND METHODS: This retrospective observational study analyzed clinical characteristics and procedures in consecutive children undergoing major ear surgery over a 3-year period in a teaching hospital. The study followed STROBE recommendations. RESULTS: We included 214 day-cases from a total population of 271 children. Median age was 109±44months (9years) [range: 8-196months (16years)]. In 57% of cases, the procedure was performed without mastoidectomy: 84 myringoplasties and 37 tympanoplasties. In 43% of cases, mastoidectomy was associated: 47 cochlear implants and 46 closed tympanoplasties for cholesteatoma. Ninety-five percent of day-surgeries were successful; in 5%, there was crossover to pediatric ENT department admission, for the following symptoms: postoperative nausea and vomiting in 3 cases, pain in 3, and late awakening in 5. Univariate analysis showed a relationship between failure and age under 36months (P=0.002). There were no readmissions. There were unscheduled consultations in 3% of cases: for minor otorrhagia in 5 cases and uncomplicated otorrhea in 2. CONCLUSION: Major otologic surgery in children is compatible with day-surgery. Younger patients, usually candidates for cochlear implantation, had greater risk of crossover to conventional admission. In this age group, scheduling should be earlier in the morning, with rigorous postoperative nausea and vomiting prophylaxis.


Subject(s)
Cholesteatoma, Middle Ear , Otologic Surgical Procedures , Adult , Ambulatory Surgical Procedures , Child , Cholesteatoma, Middle Ear/surgery , Humans , Postoperative Nausea and Vomiting/complications , Postoperative Nausea and Vomiting/surgery , Retrospective Studies , Treatment Outcome , Tympanoplasty/methods
2.
Eur Ann Otorhinolaryngol Head Neck Dis ; 137(3): 177-181, 2020 May.
Article in English | MEDLINE | ID: mdl-32312676

ABSTRACT

OBJECTIVE: Joint guidelines of the French Pediatric Otolaryngology Society (AFOP) and of the French Society of otorhinolaryngology-head and neck surgery (SFORL) on the management of paediatric otolaryngology patients in the context of the COVID-19 pandemic. METHODS: A nation-wide workgroup drew guidelines based on clinical experience, national and local recommendations and scientific literature. Proposals may have to be updated on a day-to-day basis. RESULTS: In children, incidence of symptomatic COVID-19 (1-5%) is low and of good prognosis. The indications for nasal flexible endoscopy should be drastically limited. If undertaken, full Personal Protective Equipment (PPE) including FFP2 masks are required, as well as use of a sheath. Saline nose wash done by caregivers other than parents at home should require PPE. Unless foreign body tracheobronchial aspiration is clinically obvious, CT-scan should be performed to confirm indication of endoscopy. Surgical indications should be limited to emergencies and to cases that cannot be delayed beyond 2 months (especially endonasal, endopharyngeal laryngo-tracheobronchial procedures). Postponement should ideally be a group decision and recorded as such in the medical file. Surgical techniques should be adapted to limit the risk of viral dissemination in the air, avoiding the use of drills, microdebriders, monopolar cautery or lasers. Continuous suction should be placed near the operating field. In case of confirmed Covid-19 cases, or suspected cases (or in some centres systematically), PPE with FFP2 mask should be worn by all staff members present in the operating room.


Subject(s)
Coronavirus Infections/prevention & control , Otolaryngology/methods , Otolaryngology/standards , Pandemics/prevention & control , Pediatrics/methods , Pediatrics/standards , Pneumonia, Viral/prevention & control , Betacoronavirus/isolation & purification , COVID-19 , Child , Coronavirus Infections/epidemiology , Coronavirus Infections/transmission , Coronavirus Infections/virology , France/epidemiology , Humans , Infection Control/methods , Infection Control/standards , Pneumonia, Viral/epidemiology , Pneumonia, Viral/transmission , Pneumonia, Viral/virology , SARS-CoV-2
3.
Eur Ann Otorhinolaryngol Head Neck Dis ; 137(2): 117-121, 2020 Mar.
Article in English | MEDLINE | ID: mdl-32114087

ABSTRACT

INTRODUCTION: The authors present the guidelines of the French Society of Otorhinolaryngology (SFORL) for clinical and radiological assessment of cystic neck lymphadenopathy of unknown primary in adults. Most cases concern head and neck carcinoma metastasis, often in the oropharyngeal area, or less frequently differentiated thyroid carcinoma or non-keratinizing nasopharyngeal carcinoma. METHODS: A multidisciplinary task force was commissioned to carry out a review of the literature on the etiological work-up in cystic neck lymphadenopathy in adults: clinical examination, conventional imaging (ultrasound, CT, MRI) and metabolic imaging. Guidelines were drafted based on the articles retrieved, and graded A, B, C or expert opinion according to decreasing level of evidence. RESULTS: Oriented clinical examination, cervical and thyroid ultrasound scan and contrast-enhanced neck and chest CT scan are recommended in the assessment of cystic neck lymphadenopathy of unknown primary in adult patients. PET-CT is recommended prior to panendoscopy, to identify the primary tumor. CONCLUSION: Clinical and radiological assessment is fundamental for etiologic diagnosis of cystic neck lymphadenopathy in adult patients, and should be completed by cytological examination before in initiating treatment.


Subject(s)
Cysts/diagnosis , Lymphadenopathy/diagnosis , Cysts/diagnostic imaging , Cysts/etiology , Humans , Lymphadenopathy/diagnostic imaging , Lymphadenopathy/etiology , Neck
4.
Eur Ann Otorhinolaryngol Head Neck Dis ; 136(4): 289-294, 2019 Sep.
Article in English | MEDLINE | ID: mdl-31420238

ABSTRACT

OBJECTIVES: To present the guidelines of the French Society of Otolaryngology-Head and Neck Surgery concerning the use of non-steroidal anti-inflammatory drugs (NSAIDs) in pediatric ENT infections. METHODS: Based on a critical analysis of the medical literature up to November 2016, a multidisciplinary workgroup of 11 practitioners wrote clinical practice guidelines. Levels of evidence were classified according to the GRADE (Grades of Recommendation, Assessment, Development and Evaluation) system: GRADE A, B, C or "expert opinion". The first version of the text was reworked by the workgroup following comments by the 22 members of the reading group. RESULTS: The main recommendations are: NSAIDs are indicated at analgesic doses (e.g. 20-30 mg/kg/day for ibuprofen) in combination with paracetamol (acetaminophen) in uncomplicated pediatric ENT infections (acute otitis media, tonsillitis, upper respiratory infections, and maxillary sinusitis) if: o pain is of medium intensity (visual analogue scale (VAS) score 3-5 or "Evaluation Enfant Douleur" (EVENDOL) child pain score 4-7) and insufficiently relieved by first-line paracetamol (residual VAS≥3 or EVENDOL≥4); o pain is moderate to intense (VAS 5-7 or EVENDOL 7-10). When combined, paracetamol and ibuprofen are ideally taken simultaneously every 6h. It is recommended: (1) o not to prescribe NSAIDs in severe or complicated pediatric ENT infections; (2) o to suspend NSAIDs treatment in case of unusual clinical presentation of the infection (duration or symptoms); (3) o not to prescribe NSAIDs for more than 72h.


Subject(s)
Anti-Inflammatory Agents, Non-Steroidal/administration & dosage , Pediatrics , Acetaminophen/therapeutic use , Analgesics, Non-Narcotic/therapeutic use , Anti-Inflammatory Agents, Non-Steroidal/adverse effects , Contraindications, Drug , Dose-Response Relationship, Drug , Drug Interactions , Drug Therapy, Combination , Empyema, Subdural/drug therapy , France , Humans , Lymphadenitis/drug therapy , Meningitis/drug therapy , Otitis/drug therapy , Pain Measurement , Respiratory Tract Infections/drug therapy , Societies, Medical
5.
Eur Ann Otorhinolaryngol Head Neck Dis ; 136(6): 489-496, 2019 Nov.
Article in English | MEDLINE | ID: mdl-31186166

ABSTRACT

OBJECTIVES: The authors present the guidelines of the French Society of Otorhinolaryngology - Head and Neck Surgery Society on diagnostic procedures for lymphadenopathy in case of a cervical mass with cystic aspect. METHODS: A multidisciplinary work-group was entrusted with a review of the scientific literature on the topic. Guidelines were drawn up, then read over by an editorial group independent of the work-group, and the final version was drawn up. Guidelines were graded as A, B, C or expert opinion, by decreasing level of evidence. RESULTS: In adults presenting a cystic cervical mass, it is recommended to suspect cervical lymphadenopathy: in order of decreasing frequency, cystic metastasis of head and neck squamous cell carcinoma, of undifferentiated nasopharyngeal carcinoma, and of thyroid papillary carcinoma (Grade C). On discovery of a cystic cervical mass on ultrasound, architectural elements indicating a lymph node and a thyroid nodule with signs of malignancy should be screened for, especially if the mass is located in levels III, IV or VI (Grade A). Malignant lymphadenopathy should be suspected in case of cervical mass with cystic component on CT (Grade B), but benign or malignant status cannot be diagnosed only on radiological data (CT or MRI) (Grade A), and 18-FDG PET-CT should be performed, particularly in case of inconclusive ultrasound-guided fine needle aspiration biopsy (Grade C).


Subject(s)
Head and Neck Neoplasms/diagnosis , Lymphadenopathy/diagnosis , Adult , Biopsy, Fine-Needle , Diagnosis, Differential , Fluorodeoxyglucose F18 , Head and Neck Neoplasms/pathology , Head and Neck Neoplasms/surgery , Humans , Image-Guided Biopsy , Lymphadenopathy/pathology , Lymphadenopathy/surgery , Magnetic Resonance Imaging , Nasopharyngeal Neoplasms/diagnosis , Nasopharyngeal Neoplasms/pathology , Nasopharyngeal Neoplasms/surgery , Oropharyngeal Neoplasms/diagnosis , Oropharyngeal Neoplasms/pathology , Oropharyngeal Neoplasms/surgery , Positron Emission Tomography Computed Tomography , Sensitivity and Specificity , Thyroid Cancer, Papillary/diagnosis , Thyroid Cancer, Papillary/pathology , Thyroid Cancer, Papillary/surgery , Thyroid Neoplasms/diagnosis , Thyroid Neoplasms/pathology , Thyroid Neoplasms/surgery , Tomography, X-Ray Computed , Ultrasonography
6.
Eur Ann Otorhinolaryngol Head Neck Dis ; 136(3): 161-164, 2019 Jun.
Article in English | MEDLINE | ID: mdl-30880034

ABSTRACT

OBJECTIVE: To assess ossiculoplasty results in children and screen for predictive factors of efficacy. PATIENTS AND METHODS: Seventy five children undergoing ossiculoplasty between 2001 and 2014 in a pediatric ENT department were included. The following data were collected and analyzed: demographic data, surgical indication, history of tympanoplasty, contralateral ear status (healthy, affected), preoperative hearing thresholds, surgical technique, intraoperative findings, and ossicular chain status at eardrum opening. Audiological results were reported according to American Academy of Otolaryngology-Head and Neck Surgery guidelines. RESULTS: Forty eight patients were included in the total ossicular reconstruction prosthesis (TORP) group. Mean age at surgery was 9.9years. Mean follow up was 2.7years. Mean air-bone gap (ABG) closure to within 20dB was achieved in 40% of cases at medium term (12 to 18 months after surgery). Air conduction (AC) threshold ≤30dB was achieved in 68% of cases. AC threshold improved by 14.6dB and 8.7dB at medium and long-term follow-up, respectively. A significant correlation was found between success rate and absence of history of tympanoplasty. The success rate was higher for primary than for revision procedures. Twenty seven children were included in the partial ossicular reconstruction prosthesis (PORP) group. Mean age was 9.5years, and mean follow-up 2.6years. Mean air-bone gap (ABG) closure to within 20dB was achieved in 75% of cases at medium term. AC threshold ≤30dB was achieved in 75% of cases AC threshold improved by 9.3dB and 5dB at medium and long-term follow-up, respectively. No predictive factors for success were found in the PORP group. CONCLUSION: The present study suggested that total ossiculoplasty leads to better results when performed in first-line. It also confirmed that functional outcome is better in partial than total ossicular reconstruction prosthesis.


Subject(s)
Ear Ossicles/surgery , Hearing , Adolescent , Audiometry , Auditory Threshold , Bone Conduction/physiology , Child , Cholesteatoma, Middle Ear/surgery , Female , Follow-Up Studies , Hearing/physiology , Humans , Male , Ossicular Prosthesis , Plastic Surgery Procedures , Reoperation , Retrospective Studies , Time Factors , Treatment Outcome , Tympanoplasty/statistics & numerical data
7.
Eur Ann Otorhinolaryngol Head Neck Dis ; 131(4): 233-8, 2014 Sep.
Article in English | MEDLINE | ID: mdl-25106698

ABSTRACT

The authors present the guidelines of the French Oto-rhino-laryngology--Head and Neck Surgery Society (SFORL) regarding pain management in children and adults following tonsillectomy. A multidisciplinary work group was entrusted with a literature review. Guidelines were drawn up based on the articles retrieved and the group members' experience. They were read over by an editorial group independent of the work group. A coordination meeting drew up the final version. Guidelines were graded A, B or C or as professional agreement in decreasing order of level of evidence. At home, non-steroid anti-inflammatory drugs (NSAIDs) are recommended in association with paracetamol in elevated respiratory risk and especially obstructive sleep apnea syndrome; in elevated hemorrhagic risk (hemostasis disorder, surgical problems, etc.), tramadol is recommended. Two other treatment schedules (modified NSAIDs and corticosteroids) have not undergone dedicated study and should be assessed. Management of post-tonsillectomy pain in children is founded on individual risk/benefit analysis.


Subject(s)
Analgesics/therapeutic use , Codeine/therapeutic use , Pain Management/standards , Pain, Postoperative/drug therapy , Tonsillectomy/adverse effects , Child , Child, Preschool , Humans , Infant , Risk Assessment
8.
Eur Ann Otorhinolaryngol Head Neck Dis ; 131(4): 227-32, 2014 Sep.
Article in English | MEDLINE | ID: mdl-25106699

ABSTRACT

OBJECTIVES: The present clinical practice guidelines cover the entire field of management of post-tonsillectomy pain. Given the French and European regulatory restrictions on the use of codeine, an update appears necessary to clarify the management of post-tonsillectomy pain in adults. METHOD: A work group approached the issue of pain management, following the chronological pathway from initial consultation to postoperative period. As exhaustive a study of the literature as possible assessed the pain impact of the various surgical techniques and the efficacy of the various analgesia schedules. RESULTS: Guidelines on the management of post-tonsillectomy pain in adults were drawn up and graded, based on the levels of evidence of selected articles and on work group consensus. The guidelines stress the importance of patient information and seek to harmonize practice, reduce the risk of postoperative complications and above all improve control of post-tonsillectomy pain in adults.


Subject(s)
Pain Management/standards , Pain, Postoperative/etiology , Pain, Postoperative/therapy , Tonsillectomy/adverse effects , Adult , Humans
9.
Eur Ann Otorhinolaryngol Head Neck Dis ; 131(5): 271-5, 2014 Nov.
Article in English | MEDLINE | ID: mdl-24947745

ABSTRACT

OBJECTIVES: Congenital teratomas of the oropharyngeal cavity are extremely rare and are associated with a high neonatal mortality rate due to severe airway obstruction. Management has been improved with progress in antenatal diagnosis. The authors describe this progress in the light of a series of 4 cases and a review of the literature. METHODS: The medical charts of four neonates treated in the department since 1995 were reviewed. The following criteria were studied: age at diagnosis, clinical and radiological features of the tumour, management at birth and outcome. RESULTS: All four cases occurred in female neonates with an antenatal diagnosis in two cases, allowing preparation for endoscopy in the delivery room in one case and an EXIT procedure in the other case. Three neonates had to be intubated in the delivery room. Imaging showed invasion of the infratemporal fossa in 3 of the 4 cases. Surgical resection via various approaches to the infratemporal fossa was complete in every case. Adjuvant chemotherapy was administered in one case. CONCLUSION: Surgery for these mostly benign tumours is very challenging and requires a multidisciplinary team. Perinatal planning allows appropriate management at birth, decreasing the risk of airway obstruction. Surgery is the mainstay of treatment of teratomas.


Subject(s)
Oropharyngeal Neoplasms/pathology , Oropharyngeal Neoplasms/surgery , Teratoma/pathology , Teratoma/surgery , Chemotherapy, Adjuvant , Female , Humans , Infant, Newborn , Neoplasm Invasiveness , Oropharyngeal Neoplasms/drug therapy , Pregnancy , Prenatal Diagnosis , Respiration, Artificial , Teratoma/drug therapy
10.
Eur Ann Otorhinolaryngol Head Neck Dis ; 130(2): 67-72, 2013 Apr.
Article in English | MEDLINE | ID: mdl-23352732

ABSTRACT

INTRODUCTION: Tonsillotomy is an effective treatment for the management of obstructive sleep apnoea syndrome (OSAS) in children with tonsillar hypertrophy and appears to be associated with less pain and postoperative morbidity. OBJECTIVE: To compare postoperative morbidity and short-term and intermediate-term efficacy of radiofrequency tonsillotomy (TT) and bipolar scissors tonsillectomy (TE) in children. PATIENTS AND METHODS: Children with OSAS due to tonsillar hypertrophy were included in a prospective, non-randomized study between February 4, 2008 and March 20, 2010. Exclusion criteria were recurrent tonsillitis (≥ 3 episodes per year), clotting disorders and age less than 2 years. Postoperative complications, efficacy on OSAS, and operating times were evaluated. Pain was evaluated by the Postoperative Pain Measure for Parents score on D0, D1, D7 and D30. RESULTS: One hundred and ninety-three children were included: 105 in the TE group (age: 4.75 ± 2.37 years) and 88 in the TT group (age: 4.88 ± 2.6 years). The pain score was significantly lower in the TT group than in the TE group during the first postoperative week (P<0.05). A significant difference was observed for the secondary postoperative bleeding rate (1 after TT versus 8 after TE). No significant difference was observed between the two techniques in terms of the efficacy on OSAS. At 1 year, the tonsil regrowth rate in the TT group was 4.5%. CONCLUSION: Radiofrequency tonsillotomy is a safe technique for the treatment of obstructive tonsillar hypertrophy in children with good results on OSAS and a reduction of postoperative pain.


Subject(s)
Adenoids/surgery , Pulsed Radiofrequency Treatment , Sleep Apnea, Obstructive/surgery , Tonsillectomy/instrumentation , Tonsillectomy/methods , Adenoids/physiopathology , Chi-Square Distribution , Child , Child, Preschool , Female , Humans , Hypertrophy , Laser Therapy , Male , Pain, Postoperative/prevention & control , Postoperative Hemorrhage/prevention & control , Prospective Studies , Snoring/surgery
11.
Eur Ann Otorhinolaryngol Head Neck Dis ; 128(6): 321-3, 2011 Dec.
Article in English | MEDLINE | ID: mdl-22075621

ABSTRACT

OBJECTIVE: To describe the diagnosis and management of lingual thyroglossal duct cyst in newborns. CASE REPORT: A one-month-old girl presenting with inspiratory stridor and chest wall retraction was referred to our department for management of stridor. Upper airway endoscopy and neck CT scan showed a round mass at the base of the tongue causing upper airway obstruction. Computed tomography showed a well-circumscribed, low-density lesion at the base of the tongue. Endoscopic marsupialization of this lesion was performed under general anaesthesia. Histological examination confirmed the diagnosis of lingual thyroglossal duct cyst. No recurrence was observed 18 months after endoscopic treatment. DISCUSSION/CONCLUSION: Lingual thyroglossal duct cyst with airway obstruction is an uncommon aetiology of stridor in newborns with symptoms similar to those of laryngomalacia. The diagnosis is based on laryngoscopy. Surgical endoscopic removal is the treatment of choice. Recurrence after endoscopic treatment is rare.


Subject(s)
Thyroglossal Cyst , Tongue Diseases , Female , Humans , Infant, Newborn , Respiratory Sounds/etiology , Thyroglossal Cyst/complications , Thyroglossal Cyst/diagnosis , Thyroglossal Cyst/surgery , Tongue Diseases/complications , Tongue Diseases/diagnosis , Tongue Diseases/surgery
12.
Arch Pediatr ; 18(7): 764-6, 2011 Jul.
Article in French | MEDLINE | ID: mdl-21621989

ABSTRACT

INTRODUCTION: Inhalation of a laryngotracheobronchial foreign body is a common pediatric emergency situation. It is a source of morbidity and even mortality, especially among children under 3 years of age. CASE REPORT: A 14-month-old child presented suddenly combining bitonal dysphonia and dyspnea. Given the persistence of symptoms after 1.5 months and the normality of examinations requested by his doctor (pH, cervical ultrasonography, cervical and thoracic radiography), an ENT opinion was sought. An aerodigestive tract endoscopy was carried out in the emergency setting, finding a glottic foreign body associated with subglottic granulomas. The foreign body extraction led to the immediate disappearance of dyspnea. Dysphonia gradually improved under Budesonide aerosols. CONCLUSION: The lack of penetration syndrome in the interrogation and non specific symptoms may lead to an important diagnosis and treatment delay with dramatic consequences in case of airway foreign body. Endoscopy under general anesthesia must be practiced if there is any doubt for a thorough examination of the airways.


Subject(s)
Dysphonia/etiology , Dyspnea/etiology , Foreign Bodies/diagnosis , Larynx , Diagnosis, Differential , Foreign Bodies/therapy , Humans , Infant , Laryngoscopy , Male
13.
Ann Otolaryngol Chir Cervicofac ; 126(4): 169-74, 2009 Sep.
Article in French | MEDLINE | ID: mdl-19524875

ABSTRACT

OBJECTIVE: Mastoidectomy is the standard management for exteriorized mastoiditis. The objective of this study was to assess the results of conservative management of acute mastoiditis and to study the types of bacteria isolated and their sensitivity to antibiotics. METHODS: A retrospective study including children admitted with acute mastoiditis was conducted between 1994 and 2007. Intravenous antibiotics were systematic. Since 2002, mastoidectomy has been replaced by retroauricular puncture and grommet tube insertion. RESULTS: Forty-four children had acute mastoiditis. All but one (temporozygomatic swelling) had postauricular swelling. The culture was positive in 78% of cases. Streptococcus pneumoniae was the most common bacteria identified. Twenty-six subperiosteal abscesses were found on the CT scan. Mastoidectomy was performed in 17 cases, 16 of which took place before 2002. The hospital stay has been decreased by six days with retroauricular puncture and grommet tube insertion management. CONCLUSION: In the absence of intracranial complications and suspicion of Fusobacterium necrophorum, a retroauricular puncture and grommet tube insertion associated with antibiotic therapy is an effective alternative to mastoidectomy in the treatment of acute mastoiditis with subperiosteal abscess.


Subject(s)
Anti-Bacterial Agents/therapeutic use , Bacterial Infections/drug therapy , Bacterial Infections/surgery , Mastoid/surgery , Mastoiditis/drug therapy , Mastoiditis/surgery , Paracentesis , Adolescent , Bacterial Infections/complications , Child , Child, Preschool , Female , Humans , Infant , Length of Stay , Male , Mastoiditis/microbiology , Middle Ear Ventilation/methods , Otorhinolaryngologic Surgical Procedures/methods , Paracentesis/methods , Pneumococcal Infections/drug therapy , Pneumococcal Infections/surgery , Retrospective Studies , Risk Assessment , Risk Factors , Treatment Outcome
15.
Ann Otolaryngol Chir Cervicofac ; 123(1): 34-40, 2006 Feb.
Article in French | MEDLINE | ID: mdl-16609667

ABSTRACT

OBJECTIVES: Analyze the diagnosis and treatment of differentiated thyroid carcinomas with laryngo-tracheal invasion. MATERIALS AND METHODS: Among the 117 patients operated for a differentiated thyroid carcinoma in the ENT department of Tours Hospital (France) between January 1990 and December 2003, seven presented laryngo-tracheal invasion and were included in this retrospective study. RESULTS: Laryngo-tracheal resection resulted in a thyroid cartilage-shaving in two patients. We performed a resection of one side of the thyroid cartilage in one patient, a thyro-tracheal resection-anastomosis with a partial cricoidectomy in one patient, a partial vertical laryngectomy extended to the first tracheal ring in one patient and a total laryngectomy in one patient. No laryngo-tracheal resection was done in one patient. Early complications were swallowing disorders (n = 2), transitory hypoparathyroidism (n = 1), definitive recurrent nerve paralysis (n = 2), subcutaneous emphysema and hematoma (n = 1) and Claude Bernard-Horner's syndrome (n = 1). Locoregional recurrences (n = 2) and distant metastasis (n = 2) were discovered six months to four years after the laryngo-tracheal resection. With a mean follow-up of 40 month, four patients were alive (two disease free) two patients had died and one was lost of follow-up at three months. CONCLUSION: The frequency of locoregional recurrences and distant metastasis is higher for the differentiated thyroid carcinomas with laryngo-tracheal invasion than the others. In these cases, we performed macroscopic carcinological surgery preserving laryngeal functions as much as possible.


Subject(s)
Carcinoma/pathology , Carcinoma/surgery , Laryngeal Neoplasms/pathology , Thyroid Neoplasms/pathology , Thyroid Neoplasms/surgery , Tracheal Neoplasms/pathology , Adult , Aged , Aged, 80 and over , Anastomosis, Surgical , Carcinoma/diagnostic imaging , Female , Humans , Laryngeal Neoplasms/diagnostic imaging , Laryngeal Neoplasms/surgery , Male , Middle Aged , Neoplasm Invasiveness , Neoplasm Staging , Postoperative Complications , Retrospective Studies , Thyroid Neoplasms/diagnostic imaging , Tomography, X-Ray Computed , Tracheal Neoplasms/diagnostic imaging , Tracheal Neoplasms/surgery
16.
Ann Dermatol Venereol ; 132(1): 38-40, 2005 Jan.
Article in French | MEDLINE | ID: mdl-15746606

ABSTRACT

INTRODUCTION: Castleman's disease is a lympho-proliferative disease of unknown cause. This rare disease, usually localized, is benign and develops in the young adult. The predominant localization is mediastinal. OBSERVATION: A 15 month-old infant was referred for a left latero-cervical mass that had developed since the age of 3 months. Other than this, the clinical examination was normal. Sonography, x-ray and tomodensitometry confirmed the unique nature of the lesion and the absence of loco-regional invasion. Histology following surgical exeresis found a nodule with multiple pseudo-follicular structures. These mitosis-rich structures were arranged concentrically around a vessel and were bordered by small lymphocytes forming a crown. This histological aspect corresponded to Castleman's disease in its vascular hyaline form. Local recurrence was reported twice, 2 and 8 years later and was treated each time with surgical exeresis. Histological examination was always similar to the first. DISCUSSION: Castleman's disease has rarely been reported in infants. The cervical location, at whatever age, is far rarer than the mediastinal form. Supplementary examinations are not always of interest and basically provide information on the isolated or multicentric nature. Surgical exeresis was justified because of the diagnostic doubts and the risk of compression. Diagnosis is based on anatomopathology. Relapses have rarely been described in the literature and raise the question of the potential malignant transformation after several relapses.


Subject(s)
Castleman Disease/pathology , Castleman Disease/surgery , Neck/pathology , Neck/surgery , Child , Child, Preschool , Humans , Infant , Male , Recurrence , Time Factors
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