Adaptation Process of Male Kidney Transplant Recipients During the Difficult Postoperative Recovery Stage at Home.

BACKGROUND: Kidney transplantation is the main treatment for irreversible organ failure. It helps patients regain hope, prolongs their lives, and improves their quality of life. Because of cultural barriers, male kidney-transplant recipients in Taiwan may face a difficult adaptation process during postoperative care at home. METHODS: In this qualitative exploratory study, we employed purposive sampling of male kidney-transplant recipients that was obtained from a leading medical center in Taiwan. Semi-structured, face-to-face interviews were used to collect data, which were further content analyzed. RESULTS: All 30 qualified patients were approached and agreed to participate (age range = 29-67 years). Participants' post-kidney transplant time frame ranged from 2 to 22 years. We revealed several difficulties that participants experienced during their postoperative recovery: (1) physical and mental exhaustion and treatment side effects; (2) worry and uncertainty about rejection, graft failure, and the future; (3) fear of losing one's job and putting the family in financial trouble; and (4) impaired self-image and social barriers. Corresponding adaptation processes included (1) experiencing shock during the early post-transplantation stage, (2) re-identification of the transition period of self-value, (3) seeking support and thinking positively, (4) accepting one's new self-image, and (5) regaining autonomy. CONCLUSION: The current results can be used to improve the quality of care at home for male kidney-transplant recipients. Health care providers should assist patients in the adaptation process to reduce discomfort and relieve stress. This study can also serve as a reference for future research.

Difficulties and Coping Strategies of Kidney-transplant Recipients During Their Dark Postoperative Recovery Stage After Returning Home.

INTRODUCTION: Kidney Transplantation (KT) is the best treatment for end-stage renal disease to prolong patients' lives. To improve patients' postoperative survival rate and quality of life, postoperative care at home is vital. We explored the difficulties faced and coping strategies used by KT recipients during their dark postoperative recovery stage at home. METHODS: This qualitative, exploratory study used a purposive sample, which was obtained from a leading medical center in Taiwan. We used a semi-structured interview guide to collect data through in-depth, face-to-face interviews. Data were content analyzed. RESULTS: Fifty individuals were approached and agreed to participate (30 men, 20 women). Participants' post-KT timeframe ranged from 2 to 28 years. Seven difficulties were reported: 1. physical discomfort and treatment side-effects; 2. concern about the impact of transplant failure; 3. uncertainty about the future; 4. unbearable economic pressure; 5. concerns about becoming a family burden; 6. feeling that life lacks a purpose; and 7. feeling isolated. Coping strategies included 1. seeking assistance from health care professionals, 2. thinking positively, 3. changing one's lifestyle, 4. setting goals to divert attention, 5. seeking psychological, and 6. seeking spiritual support. CONCLUSIONS: By elucidating KT recipients' adaptability and coping strategies, we hope to improve their quality of life at home. Health care professionals should be aware of the difficulties faced by patients during their dark postoperative recovery stage and promote effective coping strategies. This study informs future research and has implications concerning the effective coordination of transplant medical teams.

Effects of prone position on inflammatory markers in patients with ARDS due to community-acquired pneumonia.

BACKGROUND/PURPOSE: Acute respiratory distress syndrome (ARDS) is a serious disorder of intensive care unit patients. We evaluated the safety of continuous prone position ventilation (PRONE) and its effects on oxygenation and plasma cytokine concentrations in patients with ARDS caused by severe community-acquired pneumonia (CAP). METHODS: This was a prospective observational clinical study conducted in a respiratory intensive care unit of a 1200-bed medical center in central Taiwan. Twenty-two patients with severe CAP and ARDS were included. They were treated by traditional supine ventilation (SUPINE, n = 11) or PRONE (n = 11) if they met the criteria for ARDS. Patients in the PRONE group were ventilated in prone position continuously for at least 72 hours. Plasma cytokines were collected and analyzed at baseline, 24 hours and 72 hours after enrolment. Serial PaO2/FiO2 and complications were evaluated. RESULTS: Complications associated with PRONE were minor and self-limited. PRONE had higher PaO2/FiO2 ratio than SUPINE did at 48 hours after enrolment. The levels of plasma IL-6 concentration declined significantly with time in the PRONE group (p = 0.011). The levels of plasma IL-6 concentration at enrolment, 24 hours and 72 hours after enrolment also predicted the 14th day mortality of all patients. CONCLUSION: PRONE was a safe and effective maneuver for improving oxygenation in patients with severe CAP and ARDS. PRONE also influenced IL-6 expression in patients with severe CAP.