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1.
J Alzheimers Dis ; 91(1): 321-343, 2023.
Article in English | MEDLINE | ID: mdl-36404547

ABSTRACT

BACKGROUND: The CERAD Word List Memory Test (WLMT) is widely used in the assessment of older adults with suspected dementia. Although normative data of the WLMT exist in many different regions of the world, normative data based on large population-based cohorts from the Scandinavian countries are lacking. OBJECTIVE: To develop normative data for the WLMT based on a large population-based Norwegian sample of healthy older adults aged 70 years and above, stratified by age, gender, and education. METHODS: A total of 6,356 older adults from two population-based studies in Norway, HUNT4 70 + and HUNT4 Trondheim 70+, were administered the WLMT. Only persons with normal cognitive function were included. We excluded persons with a diagnosis of mild cognitive impairment (MCI) and dementia, and persons with a history of stroke and/or depression. This resulted in 3,951 persons aged between 70 and 90 years, of whom 56.2% were females. Regression-based normative data were developed for this sample. RESULTS: Age, gender, and education were significant predictors of performance on the WLMT list-learning subtests and the delayed recall subtest, i.e., participants of younger age, female sex, and higher education level attained higher scores compared to participants of older age, male sex, and lower level of education. CONCLUSION: Regression-based normative data from the WMLT, stratified by age, gender, and education from a large population-based Norwegian sample of cognitively healthy older adults aged 70 to 90 years are presented. An online norm calculator is available to facilitate scoring of the subtests (in percentiles and z-scores).


Subject(s)
Cognitive Dysfunction , Dementia , Humans , Male , Female , Aged , Aged, 80 and over , Neuropsychological Tests , Memory , Cognitive Dysfunction/diagnosis , Cognitive Dysfunction/epidemiology , Norway/epidemiology , Dementia/diagnosis , Dementia/epidemiology
2.
J Alzheimers Dis ; 86(2): 589-599, 2022.
Article in English | MEDLINE | ID: mdl-35094994

ABSTRACT

BACKGROUND: Several studies have found that normative scores on the Montreal Cognitive Assessment Scale (MoCA) vary depending on the person's education and age. The evidence for different normative scores between sexes is poor. OBJECTIVE: The main aim of the study was to determine normative scores on the MoCA for Norwegian older adults stratified by educational level, age, and sex. In addition, we aimed to explore sex differences in greater detail. METHODS: From two population-based studies in Norway, we included 4,780 people age 70 years and older. People with a diagnosis of dementia or mild cognitive impairment, a history of stroke, and depression were excluded. Trained health personnel tested the participants with the MoCA. RESULTS: The mean MoCA score varied between 22 and 27 and was highest among women 70-74 years with education >13 years and lowest among men age 85 and older with education ≤10 years. Education, age, and sex were significant predictors of MoCA scores. CONCLUSION: In the present study of cognitively healthy Norwegian adults 70 years and older, we found that the normative score on the MoCA varied between 22 and 27 depending on a person's education, age, and sex. We suggest that normative scores should be determined taking these three variables into consideration.


Subject(s)
Cognitive Dysfunction , Aged , Aged, 80 and over , Cognition , Cognitive Dysfunction/diagnosis , Cognitive Dysfunction/epidemiology , Educational Status , Female , Humans , Male , Mental Status and Dementia Tests , Neuropsychological Tests
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