ABSTRACT
No disponible
Subject(s)
Humans , Male , Female , Aged, 80 and over , Coronary Occlusion/complications , Coronary Occlusion/diagnostic imaging , Self Expandable Metallic Stents , Coronary Occlusion/surgery , Angiography/methods , Balloon Valvuloplasty/methods , Aortography/methodsSubject(s)
Aortic Valve Stenosis/surgery , Coronary Angiography/methods , Coronary Occlusion/etiology , Coronary Vessels/diagnostic imaging , Heart Valve Prosthesis/adverse effects , Postoperative Complications , Aged, 80 and over , Coronary Occlusion/diagnosis , Coronary Occlusion/surgery , Coronary Vessels/surgery , Electrocardiography , Female , Follow-Up Studies , Humans , Male , Percutaneous Coronary Intervention/methods , Reoperation , Time FactorsABSTRACT
The unique physical properties of optical coherence tomography (OCT) make it a useful technique in the study of restenosis mechanisms. In fact, OCT is able to differentiate between neointimal proliferation and neoatherosclerosis within the stent. We report a rare case of occlusive neoatherosclerosis presenting beyond one year after a successful drug-eluting stent implantation. The impact of OCT findings in the clinical decision making process is emphasized.
Subject(s)
Coronary Artery Disease/therapy , Coronary Occlusion/etiology , Coronary Restenosis/etiology , Coronary Vessels/diagnostic imaging , Hypolipidemic Agents/therapeutic use , Percutaneous Coronary Intervention/instrumentation , Plaque, Atherosclerotic , Stents , Aged , Cardiovascular Agents/administration & dosage , Coronary Angiography , Coronary Artery Disease/diagnostic imaging , Coronary Occlusion/diagnostic imaging , Coronary Occlusion/therapy , Coronary Restenosis/diagnostic imaging , Coronary Restenosis/therapy , Drug-Eluting Stents , Humans , Male , Percutaneous Coronary Intervention/adverse effects , Retreatment , Sirolimus/administration & dosage , Sirolimus/analogs & derivatives , Time Factors , Tomography, Optical Coherence , Treatment OutcomeABSTRACT
OBJECTIVE: To explore the variations of brain natriuretic peptide (BNP) secretion after left atrial appendage occlusion. BACKGROUND: Left atrial appendage occlusion has been increasingly performed in the last few years, however little is known about the physiological consequences of left atrial appendage occlusion. Left atrial appendage regulates partially intravascular volume via release of brain natriuretic peptide. Brain natriuretic peptide levels have been related to increased risk of stroke in atrial fibrillation patients. METHODS: Venous blood samples were obtained in consecutive patients undergoing left atrial appendage occlusion before, 24 hr after device implantation and at the first visit after discharge (45-60 days) for BNP measurement. RESULTS: Left atrial appendage occlusion was performed in 34 patients with non-valvular atrial fibrillation and contraindication to long-term oral anticoagulation or at high-risk of bleeding. There were no differences in BNP levels between baseline and 24 hr after device implantation. However left atrial appendage closure resulted in a significant decrease in BNP levels at the first follow-up visit (45-60 days) compared to baseline measurements (759.90 pg ml(-1) vs. 636.90 pg ml(-1) , P = 0.013). CONCLUSIONS: Left atrial appendage occlusion modifies BNP levels. These levels decrease after left atrial appendage occlusion. The clinical consequences of these findings need to be evaluated in further studies. © 2015 Wiley Periodicals, Inc.
