Determination of the Rate of Penetration by Robust Machine Learning Algorithms Based on Drilling Parameters.

Underground resources, particularly hydrocarbons, are critical assets that promote economic development on a global scale. Drilling activities are necessary for the extraction and recovery of subsurface energy resources, and the rate of penetration (ROP) is one of the most important drilling parameters. This study forecasts the ROP using drilling data from three Iranian wells and hybrid LSSVM-GA/PSO algorithms. These algorithms were chosen due to their ability to reduce noise and increase accuracy despite the high level of noise present in the data. The study results revealed that the LSSVM-PSO method has an accuracy of roughly 97% and is more precise than the LSSVM-GA technique. The LSSVM-PSO algorithm also demonstrated improved accuracy in test data, with RMSE = 1.92 and R2 = 0.9516. Furthermore, it was observed that the accuracy of the LSSVM-PSO model improves and degrades after the 50th iteration, whereas the accuracy of the LSSVM-GA algorithm remains constant after the 10th iteration. Notably, these algorithms are advantageous in decreasing data noise for drilling data.

A novel directional-oriented method for predicting shear wave velocity through empirical rock physics relationship using geostatistics analysis.

This study attempts to design a novel direction-oriented approach for estimating shear wave velocity (VS) through geostatistical methods (GM) using density employing geophysical log data. The research area involves three hydrocarbon wells drilled in carbonate reservoirs that are comprised of oil and water. Firstly, VS was estimated using the four selected empirical rock physics relationships (ERR) in well A (target well), and then all results were evaluated by ten statistical benchmarks. All results show that the best ERR is Greenberg and Castagna, with R2 = 0.8104 and Correlation = 0.90, while Gardner's equation obtained the poorest results with R2 = 0.6766 and correlation = 0.82. Next, Gardner's method was improved through GM by employing Ordinary Kriging (OKr) in two directions in well A, and then Cross-Validation and Jack-knife methods (JKm and CVm, respectively) were used to assess OKr's performance and efficiency. Initially, CVm and JKm were employed to estimate Vs using the available density and its relationship with shear wave velocity, where the performance of CVm was better with R2 = 0.8865 and correlation = 0.94. In this step, some points from the original VS were used to train the data. Finally, Vs was estimated through JKm and using the relationship between the shear wave velocity of two wells near the target well, including wells B and C; however, in this step, the original shear wave velocity of the target well was completely ignored. Reading the results, JKm could show excellent performance with R2 = 0.8503 and Corr = 0.922. In contrast to previous studies that used only Correlation and R-squared (R2), this study further provides accurate results by employing a wide range of statistical benchmarks to investigate all results. In contrast to traditional empirical rock physics relationships, the developed direction-oriented technique demonstrated improved predicted accuracy and robustness in the investigated carbonate field. This work demonstrates that GM can effectively estimate Vs and has a significant potential to enhance VS estimation using density.

Numerical simulation and diagnosis geotechnical parameters of historical buildings in Najran City, Kingdom of Saudi Arabia.

This research aims to assess geoenvironmental risks and identify the primary deterioration drivers in ancient buildings in Najran City, utilizing various analytical tools to help make informed judgments. The samples extruded from historical buildings were examined using field inspection, experimental data, SEM, EDX, and XRD analyses, in addition to lab and field observations and meteorological data. The dissolution of clay minerals and salt crystallization are the key contributors to the degradation and cracking of historical buildings in Najran City, according to lab and field observations. When the daytime high temperature surpasses 44 °C, wind erosion and humidity might cause continuous wetting-drying cycles on the investigated building surfaces. Test results indicated that the average unconfined compressive strength of the extruded earthen wall samples was 2 MPa and the water absorption was within the upper allowed limit (i.e., 15%). A finite element model of a typical earthen historical building was developed using PLAXIS 3D software to assess the behavior and nonlinear response of the silty sand soil layer underlying the building and the earthen historical buildings themselves using a plastic material model. The field observations confirm the results of the simulation, which clearly explained the failure mechanism. The integrated geotechnical and numerical simulations could provide insights for assessing geoenvironmental risks, identify the primary deterioration drivers in ancient buildings, and provide an understanding of material qualities and failure causes not only in the studied area but in other similar regions elsewhere.

Smart waste management perspective of COVID-19 healthy personal protective materials in concrete for decorative landscape pavements and artificial rocks.

This paper presents a new method for determining the effect of healthy personal protective material (HPPM) stripes, such as surgical masks, protective suits, and overhead and foot covers, on the durability and physicomechanical characteristics of concrete for use in architectural forms. Because of the current global epidemic caused by coronavirus (COVID-19), the use of HPPM, such as surgical masks, protective suits, and overhead and foot covers, has increased considerably. COVID-19's second and third waves are currently affecting various countries, necessitating the use of facemasks (FM). Consequently, millions of single FM have been discharged into the wild, washing up on beaches, floating beneath the seas, and ending up in hazardous locations. The effect of stripe fibers on the physicomechanical characteristics of concrete, such as the workability, Uniaxial Compressive Strength UCS, flexural strength, impact strength, spalling resistance, abrasion resistance, sorptivity, Water absorption Sw, porosity (ηe), water penetration, permeability, and economic and eco-friendly aspects, need to be determined. With a focus on HPPM, especially single-use facemasks, this study investigated an innovative way to incorporate pandemic waste into concrete structures. Scanning electron microscope and X-ray diffraction patterns were employed to analyze the microstructures and interfacial transition zones and to identify the elemental composition. The HPPM had a pore-blocking effect, which reduced the permeability and capillary porosity. Additionally, the best concentrations of HPPM, particularly of masks, were applied by volume at 0, 1, 1.5, 2.0, and 2.5%. The use of mixed fibers from different HPPMs increased the strength and overall performance of concrete samples. The tendency of growing strength began to disappear at approximately 2%. The results of this investigation showed that the stripe content had no effect on the compressive strength. However, the stripe is critical for determining the flexural strength of concrete. The UCS increased steadily between 1 and 1.5% before falling marginally at 2.5%, which indicates that incorporating HPPM into concrete had a significant impact on the UCS of the mixture. The addition of HPPM to the mixtures considerably modified the failure mode of concrete from brittle to ductile. Water absorption in hardened concrete is reduced when HPPM stripes and fibers were added separately in low-volume fractions to the concrete mixture. The concrete containing 2% HPPM fibers had the lowest water absorption and porosity percentage. The HPPM fibers were found to act as bridges across cracks, enhancing the transfer capability of the matrices. From a technological and environmental standpoint, this study found that using HPPM fibers in the production of concrete is viable.

Evaluation insight into Abu Zenima clay deposits as a prospective raw material source for ceramics industry: Remote Sensing and Characterization.

The rapid development and mutations have heightened ceramic industrialization to supply the countries' requirements worldwide. Therefore, the continuous exploration for new reserves of possible ceramic-raw materials is needed to overwhelm the increased demand for ceramic industries. In this study, the suitability assessment of potential applications for Upper Cretaceous (Santonian) clay deposits at Abu Zenima area, as raw materials in ceramic industries, was extensively performed. Remote sensing data were employed to map the Kaolinite-bearing formation as well as determine the additional occurrences of clay reserves in the studied area. In this context, ten representative clayey materials from the Matulla Formation were sampled and examined for their mineralogical, geochemical, morphological, physical, thermal, and plasticity characteristics. The mineralogical and chemical compositions of starting clay materials were examined. The physicochemical surface properties of the studied clay were studied utilizing SEM-EDX and TEM. The particle-size analysis confirmed the adequate characteristics of samples for white ceramic stoneware and ceramic tiles manufacturing. The technological and suitability properties of investigated clay deposits proved the industrial appropriateness of Abu Zenima clay as a potential ceramic raw material for various ceramic products. The existence of high kaolin reserves in the studied area with reasonable quality and quantity has regional significance. It would significantly help reduce the manufacturing cost and overwhelm the high consumption rate. The ceramic manufacturers in the investigated areas are expected to bring steady producers into the industry in the long term to gain the advantage of low-cost raw materials, labor, and factory construction.

Long-acting intraocular Delivery strategies for biological therapy of age-related macular degeneration.

As one of the leading causes of central vision loss in elderly population, worldwide cases of age-related macular degeneration (AMD) have seen a dramatic increase over the past several years. Treatment regimens for AMD, especially with biological agents, are complicated due to anatomical and physiological barriers, as well as administration of high doses and frequent regimens. Some clinical examples include monthly intravitreal administration of anti-VEGF antibody ranibizumab (Lucentis®) from Genentech and aflibercept (Eylea®) from Regeneron Pharmaceuticals. Long-acting sustained intraocular drug delivery provides promising solutions, such as Vitrasert® from Bausch & Lomb, an intravitreal biodegradable polymeric implant made from poly(D,L-lactic co glycolic acid) (PLGA), and can be used as a guiding reference to formulate sustained delivery systems. In this review, we discuss the anatomy and physiology of the eye, barriers to delivery, pathology of AMD, opportunities for biological therapeutics, and future prospects of intraocular delivery strategies that are in development for treatment of AMD.

Nanopillared Chitosan/Gelatin Films: A Biomimetic Approach for Improved Osteogenesis.

Biomimicry strategies, inspired from natural organization of living organisms, are being widely used in the design of nanobiomaterials. Particularly, nonlithographic techniques have shown immense potential in the facile fabrication of nanostructured surfaces at large-scale production. Orthopedic biomaterials or coatings possessing extracellular matrix-like nanoscale features induce desirable interactions between the bone tissue and implant surface, also known as osseointegration. In this study, nanopillared chitosan/gelatin (C/G) films were fabricated using nanoporous anodic alumina molds, and their antibacterial properties as well as osteogenesis potential were analyzed by comparing to the flat C/G films and tissue culture polystyrene as controls. In vitro analysis of the expression of RUNX2, osteopontion, and osteocalcin genes for mesenchymal stem cells as well as osteoblast-like Saos-2 cells was found to be increased for the cells grown on nano C/G films, indicating early-stage osteogenic differentiation. Moreover, the mineralization tests (quantitative calcium analysis and alizarin red staining) showed that nanotopography significantly enhanced the mineralization capacity of both cell lines. This work may provide a new perspective of biomimetic surface topography fabrication for orthopedic implant coatings with superior osteogenic differentiation capacity and fast bone regeneration potential.

Perspective of ophthalmology residents in the United States about residency programs and competency in relation to the International Council of Ophthalmology guidelines.

PURPOSE: To evaluate the perspective of ophthalmology residents in the US about their residency programs and compare the competency of residency programs to international competency levels set by the International Council of Ophthalmology (ICO). METHODS: A cross-sectional web-based survey extracted from the ICO published competency standards was sent to program directors of ophthalmology residency programs in the US to forward it to current PGY-3, 4 residents, and residency graduates from 2011 to 2014. RESULTS: Eighty-seven responses were received, comprising 61 residents and 26 graduates. Most respondents were highly satisfied with their programs (93.6%). Clinic-based training was rated satisfactorily. Insufficient exposure to low-vision rehabilitation (38.5%), refraction and contact lenses prescription (38.5%), and vitreo-retinal surgeries (38.5%) was reported. Respondents were satisfied with their overall surgical experiences, with the vast majority (>83%) rating case volume, complexity, and variety as satisfactory or better. A significant group stated they had insufficient exposure to extra-capsular cataract extraction (26.3%), refractive surgery (19.7%), and orbital surgery (64.5%). All graduates surveyed passed their Ophthalmic Knowledge Assessment Program (OKAP) examinations, and 72% felt their residency programs adequately prepared them for the examinations. All respondents reported insufficient training in certain nonclinical areas, such as practice management, staffing, and administration skills. CONCLUSIONS: Ophthalmology residents in the US express high levels of satisfaction with their residency training programs. While most programs adequately address most ICO core objectives, certain curriculum modifications should be considered.

Perception and use of massive open online courses among medical students in a developing country: multicentre cross-sectional study.

OBJECTIVES: To assess the prevalence of awareness and use of massive open online courses (MOOCs) among medical undergraduates in Egypt as a developing country, as well as identifying the limitations and satisfaction of using these courses. DESIGN: A multicentre, cross-sectional study using a web-based, pilot-tested and self-administered questionnaire. SETTINGS: Ten out of 19 randomly selected medical schools in Egypt. PARTICIPANTS: 2700 undergraduate medical students were randomly selected, with an equal allocation of participants in each university and each study year. PRIMARY AND SECONDARY OUTCOME MEASURES: Primary outcome measures were the percentages of students who knew about MOOCs, students who enrolled and students who obtained a certificate. Secondary outcome measures included the limitations and satisfaction of using MOOCs through five-point Likert scale questions. RESULTS: Of 2527 eligible students, 2106 completed the questionnaire (response rate 83.3%). Of these students, 456 (21.7%) knew the term MOOCs or websites providing these courses. Out of the latter, 136 (29.8%) students had enrolled in at least one course, but only 25 (18.4%) had completed courses earning certificates. Clinical year students showed significantly higher rates of knowledge (p=0.009) and enrolment (p<0.001) than academic year students. The primary reasons for the failure of completion of courses included lack of time (105; 77.2%) and slow Internet speed (73; 53.7%). Regarding the 25 students who completed courses, 21 (84%) were satisfied with the overall experience. However, there was less satisfaction regarding student-instructor (8; 32%) and student-student (5; 20%) interactions. CONCLUSIONS: About one-fifth of Egyptian medical undergraduates have heard about MOOCs with only about 6.5% actively enrolled in courses. Students who actively participated showed a positive attitude towards the experience, but better time-management skills and faster Internet connection speeds are required. Further studies are needed to survey the enrolled students for a better understanding of their experience.

Development of an Arabic version of the National Eye Institute Visual Function Questionnaire as a tool to study eye diseases patients in Egypt.

AIM: To develop and test an Arabic version of the National Eye Institute Visual Function Questionnaire-25 (NEI-VFQ-25). METHODS: NEI-VFQ-25 was translated into Arabic according to WHO translation guidelines. We enrolled adult consenting patients with bilateral chronic eye diseases who presented to 14 hospitals across Egypt from October to December 2012, and documented their clinical findings. Psychometric properties were then tested using STATA. RESULTS: We recruited 379 patients, whose mean age was (54.5±15)y. Of 46.2% were males, 227 had cataract, 31 had glaucoma, 23 had retinal detachment, 37 had diabetic retinopathy, and 61 had miscellaneous visual defects. Non-response rate and the floor and ceiling numbers of the Arabic version (ARB-VFQ-25) were calculated. Internal consistency was high in all subscales (except general health), with Cronbach-α ranging from 0.702-0.911. Test-retest reliability was high (intraclass correlation coefficient 0.79). CONCLUSION: ARB-VFQ-25 is a reliable and valid tool for assessing visual functions of Arabic speaking patients. However, some questions had high non-response rates and should be substituted by available alternatives. Our results support the importance of including self-reported visual functions as part of routine ophthalmologic examination.