ABSTRACT
Denervated dog gastrocnemius muscle has shown a progressive decrease in total protein content, alanine aminotransferase (AIAT), aspartate aminotransferase (AAT) and glutamate dehydrogenase (GDH) activity levels and elevation in free amino acid, ammonia, urea, glutamine contents and AMP deaminase activity levels during post-neurectemic days. The possible implications of these findings are discussed in relation to denervation atrophy.
Subject(s)
Muscle Denervation , Muscle Proteins/metabolism , Muscles/metabolism , Muscular Atrophy/metabolism , Alanine Transaminase/metabolism , Amino Acids/metabolism , Ammonia/metabolism , Animals , Aspartate Aminotransferases/metabolism , Dogs , Glutamate Dehydrogenase/metabolism , Urea/metabolismABSTRACT
Sine, triangular and square wave alternating currents were used to anaesthetize young buffalo calves. Central venous pressure, systolic and diastolic blood pressure and circulatory rate were monitored before, during and after application of currents. The square and triangular wave current produced a significant (P less than 0.01) increase in central venous pressure, mean systolic and diastolic blood pressure during electroanaesthesia. The sine wave seemed to produce these changes to a lesser degree than the other wave forms. From the results of objective evaluation of the effects produced on these physiological values, the sine wave would be preferred to the other two wave forms for producing anaesthesia in buffaloes.
Subject(s)
Buffaloes/physiology , Electronarcosis/veterinary , Hemodynamics , Animals , Blood Pressure , Central Venous Pressure , Electronarcosis/methods , Heart Rate , Male , Time FactorsABSTRACT
The standardized programme of electrical stimulation was applied to the control and denervation atrophied muscle of dog, Canis domesticus and the pattern of changes in the carbohydrate metabolism was analysed in the control (C), denervated control (DC), control stimulated (CS) and denervated stimulated (DS) gastrocnemius muscles. The programme of electrical stimulation of the control muscle has elevated glycogenolysis, glycolysis and increased the level of operation of TCA cycle with decreased mobilization of carbohydrates into hexose monophosphate pathway, indicating the setting in of trained condition. Sciatectomy, on the other hand, lowered the level of operation of glycogenolysis and decreased the utilization of carbohydrates through hexose-mono and di-phosphate pathways and TCA cycle. The programme of electrical stimulation applied to the denervated muscle has restored the utilization of carbohydrates through hexose mono and diphosphate pathways and oxidative metabolism indicating the applicability of this programme of electrical stimulation in the treatment of muscular atrophy.
