Subject(s)
Breast Neoplasms/diagnosis , Hyperpigmentation/etiology , Nipples/pathology , Paget's Disease, Mammary/diagnosis , Adult , Biomarkers, Tumor/analysis , Breast Neoplasms/chemistry , Breast Neoplasms/complications , Breast Neoplasms/surgery , Dermoscopy , Diagnosis, Differential , Female , Humans , Mastectomy, Segmental , Melanoma/diagnosis , Nipples/chemistry , Nipples/surgery , Paget's Disease, Mammary/chemistry , Paget's Disease, Mammary/complications , Paget's Disease, Mammary/surgery , Receptor, ErbB-2/analysis , Skin Neoplasms/diagnosisABSTRACT
No disponible
Subject(s)
Humans , Female , Adult , Skin Pigmentation , Immunohistochemistry/methods , Paget's Disease, Mammary/complications , Paget's Disease, Mammary/diagnosis , Paget's Disease, Mammary/therapy , Carcinoma, Ductal/diagnosis , Carcinoma, Ductal/surgery , Diagnosis, Differential , Paget's Disease, Mammary/physiopathology , Paget's Disease, Mammary/surgeryABSTRACT
Between the plasma-cell neoplasms the solitary osseous plasmocitoma represents a low percentage of the whole totality. Unlike the multiple myeloma the plasmocytoma is a lesion potencially curable. The diagnose criteria that must fulfil these lesions are detailed. The AA. report a case sitting in the lower jaw. Review of the previous 28 cases communicated in the anglo-saxon literature. Special attention is paid to the radiotherapy on this sickness.
Subject(s)
Mandible/pathology , Mandibular Neoplasms/pathology , Plasmacytoma/pathology , Adult , Aged , Female , Humans , Male , Mandible/radiation effects , Mandible/ultrastructure , Mandibular Neoplasms/radiotherapy , Mandibular Neoplasms/ultrastructure , Middle Aged , Plasmacytoma/radiotherapy , Plasmacytoma/ultrastructure , Radiation DosageABSTRACT
OBJECTIVE: To correlate liver fine needle aspiration (FNA) diagnosis with histopathological diagnosis and clinical evolution. DESIGN: Retrospective analysis of liver FNA validity, evaluating sensitivity, specificity and predictive value of the method in correlation with the clinical evolution and biopsy results. RESULTS: Malignancy was diagnosed in 46 cases (20 hepatocarcinomas and 26 liver metastases), and benign lesions in 24 patients. Ten additional cases were excluded on the grounds of insufficient material or the impossibility of establishing clinico-histological correlation. There were 6 false-negatives and one false-positive. The overall accuracy of the method was 90% with a sensitivity of 88.2% and specificity of 94%. The positive and negative predictive values of the method were 97.8 and 75%, respectively. CONCLUSIONS: Liver FNA is efficient in cases of suspected liver tumoration. The technique proved particularly useful in the present series in diagnosing liver metastases, often allowing the establishing of tumor origin.
Subject(s)
Liver/pathology , Anesthesia, Local , Biopsy, Needle/statistics & numerical data , Cytodiagnosis/statistics & numerical data , Evaluation Studies as Topic , False Negative Reactions , False Positive Reactions , Humans , Liver/diagnostic imaging , Liver Neoplasms/epidemiology , Liver Neoplasms/pathology , Liver Neoplasms/secondary , Retrospective Studies , Sensitivity and Specificity , Spain/epidemiology , Ultrasonography, InterventionalABSTRACT
Cytological characteristics are reported in the case of a 20-years-old male with pulmonary inflammatory pseudotumor (PIP) diagnosed by fine-needle aspiration (FNA) and later confirmed histologically. The patient presented a large tumor on the lower lobe of the right lung with hemoptysis, hemothorax and secondary acute anemia. The clinical-pathological profile of PIP are reviewed, along with diagnostic problems arising from the morpho-structural characteristics of the disease.
Subject(s)
Plasma Cell Granuloma, Pulmonary/pathology , Adolescent , Biopsy, Needle , Cytodiagnosis , Hemoptysis/diagnostic imaging , Hemoptysis/pathology , Humans , Lung/diagnostic imaging , Lung/pathology , Male , Plasma Cell Granuloma, Pulmonary/diagnostic imaging , Ultrasonography, InterventionalSubject(s)
Abnormalities, Multiple/genetics , Kidney/abnormalities , Abnormalities, Multiple/diagnosis , Abnormalities, Multiple/pathology , Ascites/diagnosis , Ascites/genetics , Eye Abnormalities/diagnosis , Eye Abnormalities/genetics , Female , Humans , Infant, Newborn , Karyotyping , Kidney/pathology , Pregnancy , Pregnancy Trimester, Second , Prenatal Diagnosis , Syndactyly/diagnosis , SyndromeABSTRACT
We report on two patients with acute lymphoblastic leukemia in induction chemotherapy, who developed a sepsis which led, in both cases, to death following the appearance of neurological symptoms suggesting CNS affectation. Autopsy revealed an angioinvasive disseminated aspergillosis affecting lungs, brain, myocardium, kidneys, thyroid glands in both cases, and endocardium, urinary bladder, lymph nodes, alimentary tract, nasal sinuses in one of the cases. Microbiology study of necropsic tissue showed Aspergillus flavusoryzae and likewise Candida albicans in one case. The latter finding suggest a combined fungal sepsis caused to candida and aspergillus.