An index-based short-form of the WISC-IV with accompanying analysis of the reliability and abnormality of differences.

OBJECTIVES: To develop an Index-based, seven subtest, short-form of the Wechsler intelligence scale for children fourth edition (WISC-IV) that offers the same comprehensive range of analytic methods available for the full-length version. DESIGN AND METHODS: Psychometric. RESULTS: The short-form Indexes had high reliability and criterion validity. Scores are expressed as Index scores and as percentiles. Methods are provided that allow setting of confidence limits on scores, and analysis of the reliability and abnormality of Index score differences. The use of the short-form is illustrated with a case example. A computer programme (that automates scoring and implements all the analytical methods) accompanies this paper and can be downloaded from the following web address: http://www.abdn.ac.uk/~psy086/dept/sf_wisc4.htm. CONCLUSIONS: The short-form will be useful when pressure of time or client fatigue precludes use of a full-length WISC-IV. The accompanying computer programme scores and analyses an individual's performance on the short-form instantaneously and minimizes the chance of clerical error.

Ultrasound validation of maneuvers to increase internal jugular vein cross-sectional area and decrease compressibility.

OBJECTIVES: The aim of this study is to determine which maneuvers result in greatest cross-sectional area (CSA) of the internal jugular vein (IJV) and reduce collapsibility as measured by ultrasound during simulated venipuncture. METHODS: A total of 52 healthy adult volunteers were prospectively studied in an academic emergency department. Cross-sectional area of the IJV was recorded at baseline, with Valsalva, hepatic pressure, and a combination of hepatic pressure plus Valsalva. Subjects were studied in supine and Trendelenburg. Measurements were repeated using pressure applied to the ultrasound transducer to simulate venipuncture and evaluate degree of IJV collapse. Repeated measures analysis of variance models were used to assess the effects of the maneuvers on the diameter equivalent of the cross-sectional area (CRADE). RESULTS: With simulated venipuncture, both Valsalva and Trendelenburg position were significantly (P < .0001) associated with increased CSA of the IJV. Valsalva in either Trendelenburg or supine position was associated with the largest CRADE (1.20 and 1.13 cm, respectively). Without simulated venipuncture, CSA of the IJV were increased in all settings (P < .0001), but the relative impacts of Valsalva and Trendelenburg position were similar. Hepatic pressure had no impact on CSA of the IJV (P = .94). CONCLUSIONS: All maneuvers with the exception of hepatic pressure led to a statistically significant increase in IJV CSA as compared with baseline with and without simulated venipuncture. Valsalva was the only maneuver, when used alone or in combination, to increase the CSA by greater than 50% and prevent collapse by 50% or more under simulated venipuncture.

Formal testing and utilization of streaming media to improve flight crew safety knowledge.

Increased concerns over the safety of air medical transport have prompted development of novel ways to increase safety. The objective of our study was to determine if an Internet streaming media safety video increased crew safety knowledge. 23 out of 40 crew members took an online safety pre-test, watched a safety video specific to our program and completed immediate and long-term post-testing 6 months later. Mean pre-test, post-test and 6 month follow up test scores were 84.9%, 92.3% and 88.4% respectively. There was a statistically significant difference in all scores (p

Pyridoxine-dependent seizures: a family phenotype that leads to severe cognitive deficits, regardless of treatment regime.

The neuropsychological and clinical histories of three male siblings affected by pyridoxine-dependent seizures with known homozygous antiquitin mutations are presented. Neuropsychological evaluation is reported from when the siblings were 11, 9, and 7 years of age. Two of the siblings had received early pyridoxine treatment (antenatal, 2-4 wks into pregnancy) and one had received late treatment (2mo postnatal). However, there was no differential effect on cognitive outcome, with all three siblings having moderate to severe learning disability. Unlike previously reported cases that received early postnatal treatment, none of the siblings had relatively preserved non-verbal cognitive skills. Equally, their intellectual performance over time did not increase above the 1st centile despite high maintenance doses of vitamin B6 (range 16-26 mg/kg/d), and mild sensory neuropathy was reported on nerve conduction studies. The findings in these siblings challenge assumptions that early and high dose pyridoxine treatment can benefit cognition in this population and suggest routine electromyography monitoring may be beneficial.

How do specific memory disorders present in the school classroom?

Childhood memory disorders have received increasing empirical investigation over recent years and reviews of the dissociations within the developmental memory system are now available. However, there are few descriptions within the literature of children's consequent behavioural and learning difficulties within an educational context. This paper reviews the growing evidence that links specific memory disorders to academic skills and then provides clinical descriptions of the day-to-day behaviour and learning often observed following the identification of such children. It is anticipated that such descriptions will allow professionals to understand the range of consequences possible and alert health and educational staff to children at risk of suffering unidentified memory difficulties. A clinical description of the behavioural repertoire associated with different childhood memory disorders is also necessary to consider how professionals may design rehabilitative support.

Designing clinical interventions for children with specific memory disorders.

Despite increasing research into the severe effects of childhood memory disorders, there is currently a paucity of evidence available to inform the design of appropriate rehabilitation strategies. Indeed, within the paediatric literature there is no model that links specific memory disorders with hypotheses for appropriate rehabilitation strategies. This paper introduces a series of intervention hypotheses based on an examination of the strengths and weaknesses associated with each type of childhood memory disorder, including short-term phonological, visuo-spatial, central executive and long-term semantic and episodic memory. Guidance is provided for integrating the hypotheses within practical rehabilitation strategies and case studies are described to examine a number of the hypotheses.

Immediate effects of methylphenidate on cognitive attention skills of children with attention-deficit-hyperactivity disorder.

This study investigated the immediate effects of stimulant medication (methylphenidate) on cognitive attention processes in children with attention-deficit-hyperactivity disorder (ADHD). Thirteen males and two females (mean age 9 y 5 mo, SD 18.3 mo) with a diagnosis of ADHD and who were to be prescribed methylphenidate were assessed twice on one day with the Test of Everyday Attention for Children, a neuropsychological battery designed to tap different aspects of cognitive attention. Between assessments, the children were administered methylphenidate (10 mg). Each child had at least average intelligence (IQ 80 or over, as measured by the Wechsler Intelligence Scale for Children-III UK) and was on no other medication. A group of 16 children, who were matched for age, sex, and intelligence, also performed the cognitive tests twice on the same day to control for practice effects of testing. At the first assessment, children with ADHD demonstrated significant impairments in several aspects of cognitive attention in comparison with the control group, particularly sustained attention. After administration of methylphenidate for the children with ADHD, they showed significant improvements in their performance on measures of cognitive attention compared to controls. The immediate effects of methylphenidate and the significance of measuring cognitive aspects of attention as well as behavioural measures are discussed.