ABSTRACT
A soft tissue infection caused by Kluyvera species in a previously healthy woman is described. Successful treatment required incision and drainage of the wound in addition to administration of antibiotics. Kluyvera species are indole positive, Voges-Proskauer negative members of the family Enterobacteriaceae. Previous reports of infection due to Kluyvera species suggest that the organism is never more than an opportunistic pathogen; however, we report the first case of infection in a previously healthy host.
Subject(s)
Enterobacteriaceae/classification , Wounds, Penetrating/microbiology , Accidents, Home , Adult , Enterobacteriaceae/isolation & purification , Female , Forearm , HumansABSTRACT
Heparin therapy is currently a vital component in the medical management of thromboembolic events. Despite its widespread use, it is associated with relatively few complications, and these are usually minor and quickly reversible. Recently a much more dramatic and serious complication of heparin therapy has been identified. In heparin-induced thrombocytopenia with associated thrombosis or "white clot syndrome," patients have paradoxic thromboembolic events while receiving heparin. These events are of acute onset and of major consequence, often resulting in limb loss or death. This paper describes our own experience with ten patients in whom the white clot syndrome occurred during heparin therapy for thrombotic or embolic events. Both porcine and bovine heparin preparations were being given through various routes. In the three cases in which platelet aggregation testing was completed, results were positive. Our ten patients ultimately had a 20% major limb amputation rate and an overall 50% mortality.
Subject(s)
Heparin/adverse effects , Thrombocytopenia/chemically induced , Thrombosis/chemically induced , Aged , Female , Humans , Middle Aged , Platelet Aggregation/drug effects , Platelet Count , Syndrome , Thrombocytopenia/blood , Thrombocytopenia/diagnosis , Thrombosis/blood , Thrombosis/diagnosisABSTRACT
This unusual case of a gangrenous round ligament manifested by acute abdominal symptoms underscores the importance of the recent radiologic descriptions of the round ligament in computerized tomography and ultrasonography. The cause of the gangrenous process in this case remains unresolved.