Factors influencing nearshore hypoxia in the southeastern Arabian Sea: A sensor-based study.

Seasonal upwelling and the associated incursion of hypoxic waters into the coastal zone is a widely studied topic over different upwelling zones. However, its persistence or variations over short time scales are poorly addressed. The present study, therefore, brings out a first report on hourly variations in the temperature, salinity and dissolved oxygen recorded by an environmental data buoy equipped with sensors, deployed in the nearshore waters of Alappuzha (southeastern Arabian Sea) from April to August 2022. The characteristic feature of the Alappuzha coast is the development of mud banks during the southwest monsoon, providing a tranquil environment suitable for continuous sensor-based measurements when the sea remains turbulent elsewhere. The results showed that despite an advance in the upwelling intensity, there is a significant variation in the oxygen concentration in the study domain on a diurnal scale. In general, the nearshore region was under hypoxia during the first half of the day (00:00 to 12:00 h), which increased steadily to reach normoxic and supersaturated levels during the rest of the day (12:00 to 24:00 h). Statistical analysis showed that winds significantly correlate to the coastal environment's subsurface oxygen concentration. During the morning hours, the wind was weak, and the water column remained stratified over the subsurface hypoxic water layer. The situation changed in the afternoon (12:00 h onwards), as there was a steady increase in the local wind speed (>5 m/s), which was sustained during the rest of the day. A local wind speed >5 m/s can disturb the stratification and enhance the mixing process from 12:00 to 24:00 h. The total kinetic energy of 11.5 J/m3 is the threshold for this oxygen supersaturation. These findings emphasize the role of wind-induced mixing in alleviating coastal hypoxia, highlighting the need for further biogeochemical and ecological investigations into the impacts of alternating oxic-hypoxic conditions in nearshore waters.

Symptomatology and Demographic Profile of COVID-19 Patients Admitted to a Tertiary Care Center in India: A Hospital Record-Based Study.

INTRODUCTION: Since its arrival in late 2019, COVID-19 has caused more than 760 million cases and nearly seven million deaths worldwide. As a novel infection research is still underway to understand the epidemiology of COVID-19. The present study was conducted in a tertiary care center in south India to understand the symptomatology of the disease in a local context. METHODS: Information for the study was retrieved from the hospital records of the Kunhitharuvai Memorial Charitable Trust (KMCT) COVID Hospital, Kerala, India, of patients admitted from 1st May 2021 to 31st October 2021 (six months). Data on their clinico-demographic profile and treatment outcomes were collected and entered into a proforma. RESULTS: Out of the 2744 patients included in the study, the proportion of males and females was comparable. About 38.6% of patients were above 60 years of age. The most common presenting complaints were fever, cough, and breathlessness. About 2.7% were asymptomatic. The mortality rate during the study period was 4.8% (132 deaths). CONCLUSION: The present study highlights differences in the symptomology and other demographic features of COVID-19 patients admitted to a hospital in Kerala, India, compared to other regional, national, and international studies. Despite limitations, these differences may have important implications for diagnosing and managing COVID-19 patients in the region.

Nurses as Warriors: Challenges and Impacts among Kerala Nurses during Coronavirus Disease-2019 Pandemic.

Introduction: In December 2019, the global outbreak of coronavirus disease-2019 (COVID-19) was announced. The pandemic has cast a spotlight like never before on health-care professionals in general, and nurses in particular. Nurses have been dubbed "warriors" by the general public for their determination to provide frontline care to patients with the disease, despite the risk of exposure and a lack of professional resources. The goal of the study was to assess the obstacles and consequences faced by Kerala nurses during the COVID-19 pandemic. Materials and Methods: A cross-sectional study was conducted from January to June 2021 among Kerala nurses. A total of 1630 nurses were chosen using a randomized sampling technique. The data were gathered using a semi-structured self-reported questionnaire. The information was entered into a database and analyzed using SPSS program version 16.0. Results: After analyzing the data, seven themes emerged: (a) love for the profession; (b) frustration for being labeled as "COVID Nurses"; (c) fear of infection and transmission; (d) personal protective equipment uncertainty; (e) workplace safety especially against hospital violence; (f) burnout in nurses; and (g) job stress. Conclusion: Nurses undertook a hazardous rescue mission and played an essential contribution in COVID-19 pandemic. Over the course of intensive work, they underwent significant psychological changes. Nurses burnout and occupational stress must be addressed with effective interventions. In order to mitigate the pandemic, the administration should also promote a healthy workplace and have a positive attitude and harmonious connection with the frontline personnel.

Oil pollution in the Eastern Arabian Sea from invisible sources: A multi-technique approach.

The Eastern Arabian Sea (EAS) is affected by oil pollution, as often evidenced by the presence of tarballs along the West Coast of India (WCI). Tarball samples collected during May 2017 along the Goa coast were subject to biomarker fingerprints, and the results matched with Bombay High (BH) oil fingerprints. The present study primarily aims at identifying the potential minor spill areas using Sentinel-imagery. Interestingly, repeated occurrence of oil spills detected at two locations, perfectly matched with BH platforms. The simulated Lagrangian trajectories also depict that tarball particles have originated from those detected locations. In 2017 alone, the quantity of spilled oil was estimated to be 129,392 l. However, spills detected offshore regions of Kachchh and Mangalore were found to be caused by ships. This is the first comprehensive study, tracking the oil pollution sources in the EAS through multi-technique approach - chemical, remote sensing and numerical modeling.

Distribution and diversity of aquatic insects of Vellayani lake in Kerala.

The diversity of insect fauna of Vellayani lake in Kerala was represented by 60 species classified under 37 families and 8 orders. Among the entomofauna collected from the lake, the order Coleoptera was diverse in number of genera (22). Shannon index was highest in station 2 (3.214) and lowest (2.839) in station 4. The higher richness index was also recorded in station 2 (6.331), though the lowest species richness was observed in Station 1 (5.205). The order Ephemeroptera is represented in Vellayani lake by the families Baetidae and Caenidae, which are considered as an indicator of water quality. Of the 15 metrices selected, taxa richness, Composition measures, Tolerance and Intolerance and Functional groups were also found out for all the stations. In the present study, the percentage of Ephemeroptera, Plecoptera, Trichoptera (EPT) taxa richness and diversity remained high in Station 1, 2 and 3 but reduced drastically in stations 4 and 5. The high HBI value recorded at station 4 is due to the abundance of pollution tolerant taxa such as Chironomidae, Tabanidae, Culicidae and Anophilinae. The results of the study reveal greater diversity of aquatic entomofauna in Vellayani freshwater lake and suggest the possibility of using insects effectively for biomonitoring programmes.

Phenylalanine hydroxylase gene mutations in phenylketonuria patients from India: identification of novel mutations that affect PAH RNA.

Analysis of seven Indian phenylketonuria families has revealed four novel mutations in the phenylalanine hydroxylase gene; two affected consensus splice sequence and the 3' UTR, respectively, while the other two were single base insertion and deletion mutations, respectively. A novel 3' splice site mutation c.168-2A>G resulted in the activation of a cryptic 3' splice site that generated a premature termination codon leading to very low levels of the mutant transcript, probably due to activation of the nonsense-mediated decay (NMD) pathway. This is probably the first report of PKU caused by the activation of NMD.