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1.
J Pharm Bioallied Sci ; 13(Suppl 2): S1188-S1192, 2021 Nov.
Article in English | MEDLINE | ID: mdl-35017954

ABSTRACT

BACKGROUND: Nowadays, emergence of drug resistance might happen in the world. Hence, invention of new dental material had started by researchers for the same. The present study evaluated the antimicrobial property of green synthesized nanosilver particles against dental cariogenic microorganisms such as Streptococcus mutans and Lactobacillus acidophilus. MATERIALS AND METHODS: An in vitro study had been designed to meet the objectives. Galla Chinensis ellagic acid powder synthesized nanosilver particles (GCAgNPs) synthesized nanosilver particles were used in this study. The cariogenic bacteria S. mutans (ATCC 25175) and L. acidophilus (ATCC 4356) were used in this study. The antimicrobial activity was detected at different concentrations (1000 µg/ml, 500 µg/ml, 250 µg/ml, 125 µg/ml, and 62.5 µg/ml) by means of qualitative and quantitative methods. RESULTS: The results show a statistically significant difference between all the concentration (1000 µg/ml, 500 µg/ml, 250 µg/ml, 125 µg/ml, 62.5 µg/ml) in Galla Chinensis synthesized silver nanoparticles (GCAgNPs) in S. mutans and L. acdiophilus. Intergroup comparison of GCAgNPs shows a statistically significant difference among all the concentrations against S. mutans and L. acidophilus. CONCLUSION: GCAgNPs show antimicrobial and antibiofilm activity against S. mutans and L. acidophilus microorganisms.

2.
J Pharm Bioallied Sci ; 11(Suppl 2): S438-S441, 2019 May.
Article in English | MEDLINE | ID: mdl-31198383

ABSTRACT

AIM: The aim of this study was to evaluate the distribution of sealer at different levels of the root canal using three different sealers in a single-cone obturation technique. MATERIALS AND METHODS: Thirty freshly extracted mandibular premolar teeth were selected and access opening was performed. Working length was determined. Cleaning and shaping were done till 25 size K file followed by ProTaper till F2 size. Teeth were then obturated with matching gutta-percha points with the following sealers: Group I, 10 teeth with zinc oxide eugenol sealer; Group II, 10 teeth with AH plus sealer; and Group III, 10 teeth with NanoSeal-S sealer. Teeth were cross sectioned at 3 and 6 mm from the apex. Color photographs of sections were taken at a magnification of ×40 using a camera connected to a stereo-operating microscope and the images were transferred to a computer. Sealer distribution was observed and the canal perimeters coated or uncoated with the sealer can be calculated using a computer digital imaging system. RESULTS: Of the three groups, zinc oxide eugenol showed least sealer distribution. AH Plus and Nanoseal-S showed no significant difference between the distribution at the 3- and 6-mm levels. CONCLUSION: Both AH Plus and Nanoseal-S showed excellent sealer distribution when compared to zinc oxide eugenol.

3.
J Pharm Bioallied Sci ; 5(Suppl 2): S139-41, 2013 Jul.
Article in English | MEDLINE | ID: mdl-23956592

ABSTRACT

Hyperplasias of the mandible are usually seen in relation to the condyle or affecting one half of the mandible, such cases being described as hemimandibular hyperplasia or elongation. This article presents a rare case of hyperplasia of the right body of the mandible. The case being unique in that although being present from childhood did not cause any functional disturbances or any occlusal disharmony characteristically seen in such developmental anomalies. Here, we describe the clinical, radiographic and histopathologic findings that led to the diagnosis hyperplasia of the mandibular body and the treatment rendered to provide the esthetic correction.

4.
J Pharm Bioallied Sci ; 4(Suppl 2): S194-6, 2012 Aug.
Article in English | MEDLINE | ID: mdl-23066251

ABSTRACT

Pyogenic granuloma is tumor-like proliferation to a nonspecific infection. Clinically, pyogenic granuloma presents as sessile or pedunculated exophytic mass with a smooth or lobulated surface which has a tendency to bleed easily. These lesions tend to occur slightly more in females, frequently involving the gingiva of the maxillary region. Histologically, these lesions show an excessive proliferation of vascular type of connective tissue to a nonspecific infection. The most common treatment is surgical excision with eradication of local irritants. This case report describes a pyogenic granuloma on the labial mucosa in a 33-year-old male, discussing the clinical features and histopathologic features that distinguish this lesion from other similar oral mucosa lesions.

5.
J Pharm Bioallied Sci ; 4(Suppl 2): S285-9, 2012 Aug.
Article in English | MEDLINE | ID: mdl-23066272

ABSTRACT

AIM AND OBJECTIVE: To compare conventional and direct digital radiography (DDR) in working length measurement of the root canal and to assess the significance of the different enhancement modes provided by the software to visualize the file length. MATERIALS AND METHODS: Access cavities were prepared in 30 extracted maxillary central incisors. Size 15 k-file was introduced into the canal till it was flush with the apical foramen. The working length was calculated as 0.5 mm less than the vernier caliper measured length of each file. The files were then sealed with resin at their respective lengths. Intraoral periapical radiographs and direct digital radiographs were taken. Vernier caliper was used to measure the file length in the periapical radiographs, and standard, positive conversion, and colorize modes were used with the CDR system. A multiple regression analysis was conducted to give an accurate analysis between the actual file length and the different groups. RESULTS: There was no statistical significance between the different groups tested. The multiple regression analysis test showed that the positive and colorize modes more accurately corresponded to the actual file length. CONCLUSION: Both conventional radiography and DDR can be reliably used for working length determination. The positive and colorize modes enhancement features of DDR greatly improve the visual perception, leading to more accurate measurements.

6.
J Pharm Bioallied Sci ; 4(Suppl 2): S406-9, 2012 Aug.
Article in English | MEDLINE | ID: mdl-23066299

ABSTRACT

A patient attending for treatment of a restorative nature may present for a variety of reasons. The success is built upon careful history taking coupled with a logical progression to diagnosis of the problem that has been presented. Each stage follows on from the preceding one. A fitting treatment plan should be formulated and should involve a holistic approach to what is required.

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