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1.
J Cancer Res Ther ; 13(6): 883-888, 2017.
Article in English | MEDLINE | ID: mdl-29237948

ABSTRACT

Identification of oral cancer at an early curable stage not only aids in controlling the mortality and morbidity rate but also improves the quality of life of the patient. Indeed, regular monitoring of such life-threatening disease has held an imperative role in cancer diagnostics. Various light-based diagnostics are currently available to the clinician for early diagnosis of oral cancer. Optical coherence tomography (OCT) is one such emerging light-based diagnostic modality that provides noninvasive, real-time images at a depth of 1.5-2 mm and can also be compared to corresponding histopathological sections, hence this procedure can also be referred as optical biopsy. This technique can also be used as an adjunct to histopathology in circumstances where large areas are needed to be examined, screening apprehensive patients, larger populations, and for regular monitoring of patients. The current article is a brief review that highlights basic principle, various versions, and applications of OCT in the diagnosis of oral cancer.


Subject(s)
Mouth Neoplasms/diagnostic imaging , Mouth Neoplasms/pathology , Tomography, Optical Coherence/methods , Biopsy , Humans , Mouth Neoplasms/therapy , Quality of Life
2.
J Clin Diagn Res ; 10(12): ZC33-ZC37, 2016 Dec.
Article in English | MEDLINE | ID: mdl-28209000

ABSTRACT

INTRODUCTION: Identifying victims in case of mass disasters when only human remains are present is quite a challenging task. Although other peripheral extremities of human body are used in estimating stature, in situations where only skull is available, teeth play an important role in personal identification. The present study used Carrea's index in stature estimation using tooth dimensions. AIM: This study is intended to correlate the anterior mandibular tooth dimensions with that of real stature using Carrea's index and also to know the applicability and validity of this index to the current study population. MATERIALS AND METHODS: A total of 82 subjects (both males and females) which makes 164 hemiarches (normal, crowded and diastema) were included. Actual height of each subject was measured using anthropometer and tooth measurements from each cast were recorded and analyzed using Carrea's index. RESULTS: The results showed a strong correlation between estimated stature and real stature. Moreover, this correlation is more valid on male sample and right side of the inferior hemiarches (Normal-81.8% and 87.2%; Crowded-76.4% and 80%; Diastema-52.9% and 60% respectively). CONCLUSION: Although a correlation between actual stature and estimated stature was established, Carrea's index as a predictor tool may not give accurate estimations. Nevertheless, it could only act as an auxiliary tool in person identification.

3.
Contemp Clin Dent ; 6(Suppl 1): S253-7, 2015 Sep.
Article in English | MEDLINE | ID: mdl-26604582

ABSTRACT

BACKGROUND: Osteoporosis is a disease characterized by low bone mass and microarchitectural deterioration of bone tissue, leading to bone fragility, and enhanced susceptibility to fractures. Dental radiographs, especially panoramic images, have been used to predict bone mineral density. A number of indices, (mandibular cortical index [MCI], mandibular cortical width [MCW], and panoramic mandibular index [PMI]) have been developed to assess and quantify the quality of mandibular bone mass and to observe the signs of resorption. OBJECTIVES: The objectives of the study were to assess mental index (MI), MCW index, and PMI with bone density in identifying risk group for osteoporosis and also to investigate influence of age and gender on MI, MCI, and PMI. MATERIALS AND METHODS: After obtaining consent, details regarding age, gender, systemic health status, and oral parafunctional habits were recorded in each patient. Then a digital panoramic radiograph was taken. The image thus obtained was subjected to calibrations and morphometric analysis using Digora version 2.7. The obtained values of indices were compared with the mean values of indices, to evaluate subjects whether they are prone to osteoporosis or not. The obtained information was subjected to statistical analysis for the significance of the parameters. RESULTS: Data analysis showed that calibration indices were highly significant in the assessment of risk group for osteoporosis than noncalibration index. The subjects at a higher risk for development of osteoporosis were old-aged adults with higher prevalence being reported in women compared to male subjects. CONCLUSION: In conclusion, our results suggest that higher percentage of subjects with undetected decreased bone mineral density may be identified based on trained general dental practitioners analyses of their panoramic radiographs using simple screening analytical calibration MI and MCI.

4.
J Clin Diagn Res ; 7(9): 2047-50, 2013 Sep.
Article in English | MEDLINE | ID: mdl-24179940

ABSTRACT

OBJECTIVE: To assess the oral and dental manifestations in non- diabetic and diabetic uraemic patients who were undergoing haemodialysis and to estimate and compare the salivary pH in these two groups. MATERIAL AND METHODS: Ninety Seven uraemic patients who were undergoing maintenance haemodialysis were included in the study. Subjective and objective findings were evaluated and recorded in a specially designed proforma. Predialytic unstimulated whole salivary pH was recorded by using pH-measuring strips. Dental health assessment consisted of DMFT and CPITN indices. RESULTS: A subjective oral manifestation of dysguesia was found to be more significant in non-diabetic patients (p<0.008). Statistically, a high significance was observed with mucosal petechiae in 31.9% patients of diabetic group .The overall DMFT score was significantly higher in diabetic group. A moderate significance was found with a CPI score of 5 (p<0.015). The pH of saliva was significantly higher among diabetic patients. CONCLUSION: The diabetic subjects who were on haemodialysis were at a high risk for developing periodontal disease and they exhibited a potential threat for dental decay and xerostomia. A lower salivary pH and a poor glycaemic control may affect their oral health. Further research is required to clarify the combined influence of diabetic nephropathy on oral health.

5.
Quintessence Int ; 43(9): 793-800, 2012 Oct.
Article in English | MEDLINE | ID: mdl-23041995

ABSTRACT

OBJECTIVE: To determine the effectiveness of aloe vera gel in the treatment of oral lichen planus when compared with triamcinolone acetonide. METHOD AND MATERIALS: A randomized, double-blind, clinical trial was designed. The study sample constituted 40 patients (23 males and 17 females) who were randomly divided into two equal groups. Group A patients received aloe vera gel, while group B patients received triamcinolone acetonide. RESULTS: Forty patients were included in the study. Most of the sample presented with erosive (n = 18) and atrophic (n = 14) variants of oral lichen planus. When clinical signs and symptoms were observed after 8 weeks of therapy, it was determined that aloe vera gel was more effective than triamcinolone acetonide in the treatment of oral lichen planus. CONCLUSION: Aloe vera gel can be considered a safe alternative treatment for oral lichen planus.


Subject(s)
Aloe , Anti-Inflammatory Agents/therapeutic use , Lichen Planus, Oral/drug therapy , Phytotherapy/methods , Plant Extracts/therapeutic use , Triamcinolone Acetonide/therapeutic use , Double-Blind Method , Female , Follow-Up Studies , Gels , Glucocorticoids/therapeutic use , Humans , Lichen Planus, Oral/physiopathology , Male , Wound Healing/drug effects
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