Subject(s)
Humans , Female , Middle Aged , Leiomyoma/diagnostic imaging , Uterine Neoplasms/diagnostic imagingABSTRACT
No disponible
Subject(s)
Humans , Coronavirus Infections/complications , Pneumonia, Viral/complications , Pandemics , Pneumothorax/virology , Pneumothorax/diagnostic imagingABSTRACT
No disponible
Subject(s)
Humans , Male , Aged, 80 and over , Prurigo/diagnosis , Prurigo/therapy , PhototherapyABSTRACT
No disponible
Subject(s)
Humans , Male , Middle Aged , Retroperitoneal Fibrosis/complications , Retroperitoneal Fibrosis/diagnostic imaging , Primary Health Care , Hematuria/etiology , Tomography, X-Ray Computed , UltrasonographyABSTRACT
No disponible
Subject(s)
Humans , Male , Adolescent , Coronavirus Infections/diagnosis , Severe acute respiratory syndrome-related coronavirus/isolation & purification , Drug Hypersensitivity/diagnosis , Sulfasalazine/adverse effects , Arthritis, Psoriatic/drug therapy , Diagnosis, Differential , Exanthema/diagnosis , Arthritis, Psoriatic/complicationsABSTRACT
No disponible
Subject(s)
Humans , Animals , Male , Adult , Occupational Diseases/diagnosis , Skin Diseases/diagnosis , Tick Bites/complications , Occupational Diseases/pathology , Preservation, Biological , Skin Diseases/pathology , Tick Bites/pathologyABSTRACT
No disponible
Subject(s)
Humans , Male , Middle Aged , Aged , Lung Neoplasms/diagnostic imaging , Primary Health Care , Lung Neoplasms/pathology , Delayed DiagnosisABSTRACT
No disponible
Subject(s)
Humans , Female , Adult , General Practitioners/organization & administration , Thyroiditis, Subacute/therapy , Thyroiditis, Subacute/diagnosisABSTRACT
La enfermedad de Crohn (EC) es un trastorno inflamatorio crónico que puede afectar a cualquier parte del tracto digestivo, desde la boca hasta el ano. Aunque se manifiesta preferentemente en íleon terminal y colon, el tracto gastrointestinal alto puede afectarse en raras ocasiones. El diagnóstico se basa en los hallazgos clínicos, endoscópicos e histológicos. El tratamiento de la EC del tracto gastrointestinal proximal es similar al indicado en la EC distal. Se emplean habitualmente glucocorticoides, asociados a inhibidores de la bomba de protones. Se expone el caso clínico de una paciente de 42 años con EC localizada en esófago, estómago y duodeno. Entre las pruebas complementarias, la endoscopia alta con toma de biopsias fue esencial para llegar al diagnóstico de EC (AU)
Crohn's disease (CD) is a chronic, inflammatory disorder that can involve any part of the gastrointestinal tract, from the mouth to the anus. Although CD mainly affects the terminal ileum and colon, the involvement of the upper gastrointestinal tract rarely occurs. Diagnosis is based on clinical, endoscopic and histological features. Treatment for CD of the upper gastrointestinal tract is similar to distal CD therapy. Corticosteroids added to proton pump inhibitors are usually used. The case of a 42-year-old female patient with CD located in the oesophagus, stomach and duodenum is presented. Among the complementary tests, an endoscopic evaluation of the upper gastrointestinal tract with biopsies was essential to support CD diagnosis (AU)
Subject(s)
Humans , Female , Adult , Crohn Disease/diagnosis , Crohn Disease/drug therapy , Glucocorticoids/therapeutic use , Endoscopy/methods , Endoscopy , Prednisone/therapeutic use , Mesalamine/therapeutic use , Gastroscopy/methods , Gastroscopy , Crohn Disease/physiopathology , Primary Health Care/methods , Primary Health Care , Sialorrhea/complications , Sialorrhea/drug therapy , Gastritis/complications , Gastritis/drug therapy , Omeprazole/therapeutic use , Amoxicillin/therapeutic useABSTRACT
La enfermedad de Creutzfeldt-Jakob (ECJ) es la encefalopatía espongiforme transmisible más frecuente en humanos. Se caracteriza clínicamente por una demencia rápidamente progresiva, mioclonías y ataxia. Las formas familiares son poco frecuentes (5-15% de los casos) y se presentan en ocasiones con síntomas atípicos y con un curso clínico más prolongado que la forma esporádica. Las pruebas complementarias recomendadas ante la sospecha clínica de ECJ son la resonancia magnética craneal, el electroencefalograma, la determinación de la proteína 14-3-3 en líquido cefalorraquídeo (LCR) y el estudio del gen de la proteína priónica (PRNP). Se expone el caso de una paciente de 54 años que presentó un trastorno depresivo prolongado asociado a un deterioro neurológico progresivo. Entre las pruebas complementarias, la elevación de la proteína 14-3-3 en LCR y el hallazgo de la mutación E200K en el estudio genético fueron esenciales para llegar al diagnóstico de una ECJ familiar (AU)
Creutzfeldt-Jakob disease (CJD) is the most frequent of the human transmissible spongiform encephalopathies. It is clinically characterized by rapidly progressive dementia, myoclonia and ataxia. Familial CJD is uncommon (5-15% of cases) and sometimes it has atypical symptoms and longer clinical course than sporadic CJD. Diagnostic tests recommended when patients present with a clinical picture of CJD are: brain magnetic resonance imaging, electroencephalogram, 14-3-3 protein determination in the cerebrospinal fluid and study of the prionic protein gene (PRNP). The case of a 54-year-old female patient with prolonged depression added to a progressive neurological impairment is presented. Among the complementary tests, cerebrospinal fluid 14-3-3 protein high level and E200K mutation discovered in genetic study were essential to support the diagnosis of familial CJD (AU)
Subject(s)
Humans , Female , Middle Aged , Creutzfeldt-Jakob Syndrome/complications , Creutzfeldt-Jakob Syndrome/diagnosis , Primary Health Care/methods , Depression/complications , Dementia/complications , Magnetic Resonance Imaging/methods , Intervertebral Disc Displacement/complications , Intervertebral Disc Displacement , Myoclonus/complications , Creutzfeldt-Jakob Syndrome/epidemiology , Brain Diseases, Metabolic/complications , Spinal Cord Compression/complications , Immunohistochemistry/methodsABSTRACT
La inmunodeficiencia común variable (ICV) es un trastorno inmunológico primario, caracterizado por niveles disminuidos de inmunoglobulinas y una mayor susceptibilidad a las infecciones. Su diagnóstico suele ser tardío, y la primera manifestación clínica habitualmente es una infección bacteriana recurrente. Aunque la mayoría de los pacientes con ICV presentan infecciones del tracto respiratorio, también pueden tener otras infecciones, como meningitis recurrentes, que pueden ser graves y presentar complicaciones. Se expone el caso clínico de una paciente de 34 años que, tras presentar una meningitis neumocócica recurrente, fue diagnosticada de ICV. La ICV es una alteración inmunológica infrecuente que, además, no suele sospecharse en la práctica habitual. Es recomendable tener en cuenta esta entidad y otros trastornos del sistema inmune ante la aparición de infecciones bacterianas de repetición no explicadas. Mediante la realización de una prueba sencilla y de fácil acceso, como el proteinograma, se puede descartar la presencia de una ICV que, sin tratamiento sustitutivo, podría tener graves complicaciones y un pronóstico desfavorable
The common variable immunodeficiency (CVI) is a primary immunological disorder characterized by decreased levels of immunoglobulins and greater susceptibility to infections. It is generally diagnosed late and the first clinical manifestation is usually a recurrent bacterial infection. Although most patients with CVI have respiratory tract infections, they may also have other infections, such as recurrent meningitis, that may be serious and half complications. A case report of a 34-year-old female patient is presented. After recurrent pneumococcal meningitis, she was diagnosed of CVI. CVI is an uncommon immunological disorder which is also not generally suspected in the usual practice. It is recommended to keep both this entity in mind as well as other disorders of the immune system when there is unexplained repeated bacterial infections. Using a simple and easily accessed test, such as the protein electrophoresis, the presence of CVI can be ruled out, which, without replacement treatment, could have serious complications and an unfavorable prognoses