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1.
Nat Commun ; 11(1): 3916, 2020 Aug 06.
Article in English | MEDLINE | ID: mdl-32764547

ABSTRACT

The demand for essential pixel components with ever-decreasing size and enhanced performance is central to current optoelectronic applications, including imaging, sensing, photovoltaics and communications. The size of the pixels, however, are severely limited by the fundamental constraints of lightwave diffraction. Current development using transmissive filters and planar absorbing layers can shrink the pixel size, yet there are two major issues, optical and electrical crosstalk, that need to be addressed when the pixel dimension approaches wavelength scale. All these fundamental constraints preclude the continual reduction of pixel dimensions and enhanced performance. Here we demonstrate subwavelength scale color pixels in a CMOS compatible platform based on anti-Hermitian metasurfaces. In stark contrast to conventional pixels, spectral filtering is achieved through structural color rather than transmissive filters leading to simultaneously high color purity and quantum efficiency. As a result, this subwavelength anti-Hermitian metasurface sensor, over 28,000 pixels, is able to sort three colors over a 100 nm bandwidth in the visible regime, independently of the polarization of normally-incident light. Furthermore, the quantum yield approaches that of commercial silicon photodiodes, with a responsivity exceeding 0.25 A/W for each channel. Our demonstration opens a new door to sub-wavelength pixelated CMOS sensors and promises future high-performance optoelectronic systems.

2.
Science ; 363(6428): 723-727, 2019 02 15.
Article in English | MEDLINE | ID: mdl-30765563

ABSTRACT

Ceramic aerogels are attractive for thermal insulation but plagued by poor mechanical stability and degradation under thermal shock. In this study, we designed and synthesized hyperbolic architectured ceramic aerogels with nanolayered double-pane walls with a negative Poisson's ratio (-0.25) and a negative linear thermal expansion coefficient (-1.8 × 10-6 per °C). Our aerogels display robust mechanical and thermal stability and feature ultralow densities down to ~0.1 milligram per cubic centimeter, superelasticity up to 95%, and near-zero strength loss after sharp thermal shocks (275°C per second) or intense thermal stress at 1400°C, as well as ultralow thermal conductivity in vacuum [~2.4 milliwatts per meter-kelvin (mW/m·K)] and in air (~20 mW/m·K). This robust material system is ideal for thermal superinsulation under extreme conditions, such as those encountered by spacecraft.

3.
Phys Rev Lett ; 121(11): 116102, 2018 Sep 14.
Article in English | MEDLINE | ID: mdl-30265090

ABSTRACT

The control of the exciton intervalley coherence renders transition metal dichalcogenides monolayers promising candidates for quantum information science. So far, generating intervalley coherence has the need for an external coherent field. Here, we theoretically demonstrate spontaneous generation (i.e., without any external field) of exciton intervalley coherence. We achieve this by manipulating the vacuum field in the vicinity of the monolayer with a designed polarization-dependent metasurface, inducing an anisotropic decay rate for in-plane excitonic dipoles. Harnessing quantum coherence and interference effects in two-dimensional materials may provide the route for novel quantum valleytronic devices.

4.
Hepatobiliary Pancreat Dis Int ; 2(2): 313-7, 2003 May.
Article in English | MEDLINE | ID: mdl-14599992

ABSTRACT

OBJECTIVE: To assess the diagnostic value of endoscopic pancreatic duct brushing in detecting mutation of the K-ras gene at codon 12 in cytologic specimens from patients with pancreatic cancer. METHODS: Thirty-five patients treated at Changhai Hospital, Shanghai between 1999 and 2001 were enrolled. Their cells obtained by pancreatic duct brushing during endoscopic retrograde cholangiopancreatography (ERCP) were suspended with phosphate buffer solution (PBS). DNA of the cells was extracted and mutation of the K-ras gene at codon 12 detected by means of PCR-SSCP. RESULTS: The K-ras gene mutation rate of pancreatic cancer was 70%, which was higher than that of chronic pancreatitis (14%, P<0.05). K-ras gene mutation was not found in patients with pancreatic cystocarcinoma and duodenum carcinoma. As to the location of pancreatic cancer, no significant difference was observed between the head, the body and tail. The sensitivity, specificity, accuracy of pancreatic duct brushing in detecting pancreatic cancer was 70%, 94%, and 83%, respectively. CONCLUSION: K-ras analysis of pancreatic brushing samples is helpful in the diagnosis of patients with early pancreatic cancer.


Subject(s)
Cholangiopancreatography, Endoscopic Retrograde/methods , Genes, ras/genetics , Pancreatic Neoplasms/genetics , Pancreatic Neoplasms/pathology , Point Mutation , Adult , Aged , Aged, 80 and over , Cholangiopancreatography, Endoscopic Retrograde/adverse effects , Chronic Disease , Female , Humans , Male , Middle Aged , Pancreatic Ducts , Pancreatitis/genetics , Pancreatitis/pathology , Polymorphism, Single-Stranded Conformational
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