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1.
Effectiveness of secukinumab for the treatment of erythrodermic psoriasis: Multicentre study in daily practice.
Reymundo, A; Armesto, S; Rodríguez, L; Baniandrés, O; Sahuquillo-Torralba, A; Torres, T; de la Cueva, P; Llamas-Velasco, M; Daudén, E.
J Eur Acad Dermatol Venereol ; 37(12): e1480-e1482, 2023 Dec.
Article in English | MEDLINE | ID: mdl-37471473

Subject(s)
Antibodies, Monoclonal, Humanized , Psoriasis , Humans , Antibodies, Monoclonal, Humanized/therapeutic use , Psoriasis/complications , Psoriasis/drug therapy , Severity of Illness Index , Treatment Outcome
2.
Effectiveness and safety profile of secukinumab for the treatment of patients with generalized pustular psoriasis in daily practice.
Reymundo, A; Vilarrasa, E; Baniandrés, O; Rodríguez-Fernández-Freire, L; Feltes, R; Llamas-Velasco, M; Daudén, E.
J Eur Acad Dermatol Venereol ; 36(10): e849-e851, 2022 10.
Article in English | MEDLINE | ID: mdl-35689497

Subject(s)
Psoriasis , Skin Diseases, Vesiculobullous , Antibodies, Monoclonal, Humanized/adverse effects , Humans , Psoriasis/drug therapy , Treatment Outcome
3.
Clinical and histological characterization of late appearance maculopapular eruptions in association with the coronavirus disease 2019. A case series of seven patients.
Reymundo, A; Fernáldez-Bernáldez, A; Reolid, A; Butrón, B; Fernández-Rico, P; Muñoz-Hernández, P; De Argila, D; Wiesner, Thomas; Llamas-Velasco, M.
J Eur Acad Dermatol Venereol ; 34(12): e755-e757, 2020 Dec.
Article in English | MEDLINE | ID: mdl-32495368

Subject(s)
COVID-19/complications , Skin Diseases/diagnosis , Skin Diseases/etiology , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Retrospective Studies , Skin Diseases/pathology , Time Factors
4.
Total synthesis of (±)-hirsutine: application of phosphine-catalyzed imine-allene [4 + 2] annulation.
Villa, Reymundo A; Xu, Qihai; Kwon, Ohyun.
Org Lett ; 14(17): 4634-7, 2012 Sep 07.
Article in English | MEDLINE | ID: mdl-22920858

ABSTRACT

The total synthesis of the indole alkaloid hirsutine has been achieved, with a key step being the application of our phosphine-catalyzed [4 + 2] annulation of an imine with ethyl α-methylallenoate. From commercially available indole-2-carboxaldehyde, the target was synthesized in 14 steps and 6.7% overall yield.


Subject(s)
Alkadienes/chemistry , Alkaloids/chemical synthesis , Imines/chemistry , Phosphines/chemistry , Alkaloids/chemistry , Catalysis , Molecular Structure , Stereoisomerism , Uncaria/chemistry
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