ABSTRACT
Strongyloides is an helminthic infection that may induce bronchospasm during systemic migration of larvae. We report a case of a 60 years old man originating from Caribbean who had corti-codependent asthma since 30 years. He was hospitalized for severe exacerbation that worsen when steroid dosage was increase. Sputum examination revealed the presence in great number of Larvae of Strongyloides stercoralis. A good clinical evolution was achieved after specific anti-helminthic treatment. Later on, it was even possible to stop completely steroid treatment. This clinical case demonstrates the interest to look for Strongyloides superinfection in asthmatic patients that worsen when receiving increasing dose of steroids. This is particularly important for patients who have resided, even many years earlier, in areas where intestinal helminthic infection are endemic.
Subject(s)
Asthma/complications , Strongyloidiasis/complications , Animals , Anti-Inflammatory Agents/therapeutic use , Antinematodal Agents/administration & dosage , Antinematodal Agents/pharmacology , Antinematodal Agents/therapeutic use , Asthma/drug therapy , Humans , Male , Middle Aged , Prednisolone/therapeutic use , Strongyloides stercoralis/drug effects , Strongyloides stercoralis/growth & development , Strongyloidiasis/diagnosis , Strongyloidiasis/drug therapy , Thiabendazole/administration & dosage , Thiabendazole/pharmacology , Thiabendazole/therapeutic use , Time FactorsABSTRACT
In 34 cases of skull traumas and in 14 cases of acute cerebral accidents, CK, GOT, GPT, LDH and its isoenzymes were assessed in the patient's serum and CSF. Results show that the increase of the enzymatic level in the CSF seems due to cerebral tissue damage for the main part, when in the serum the increase is influenced by combined traumas. The CSF dosages allow to define a threshold of severeness, unlike serum dosages without any pronostic value.