Fragilidad y riesgo de dependencia: el cuestionario de Barber en estudios poblacionales / Frailty and risk of dependency: Barber's questionnaire in population based studies

Introducción: La dependencia funcional es un problema creciente, vinculado al incremento de edad, especialmente en países industrializados. Los estudios poblacionales permiten un acercamiento a la magnitud del problema. Objetivo: El cuestionario de Barber es un instrumento ampliamente utilizado para la detección de riesgo de dependencia, vulnerabilidad o fragilidad en adultos mayores. No se han encontrado trabajos que lo apliquen en estudios poblacionales, en los que, por su sencillez, podría resultar útil. Metodología: Se incluyó el cuestionario en una encuesta de salud, con una muestra representativa (n = 1.882 sujetos) de personas de 65 años o más, de una gran ciudad (Madrid, España) y se presentan las evidencias de validez basada en la estructura interna y la relación con otras variables de tipo convergente y discriminante. Resultados: Se obtuvo una solución unifactorial, con adecuada consistencia interna según varios indicadores multivariados. Se encontraron diferencias significativas por sexo, tanto al nivel de la escala como de los ítems. También aparecieron correlaciones significativas entre la puntuación total de la prueba y la de otras variables, como la calidad de vida relacionada con la salud, la edad y la sensación de soledad. Un 58,1% de la muestra obtuvo puntuaciones que sugieren vulnerabilidad (el 65,3% de las mujeres). Conclusiones: Los resultados sugieren la utilidad del cuestionario de Barber, como prueba fiable y válida, para detectar situaciones de fragilidad o vulnerabilidad en adultos mayores, lo que facilitaría la comparabilidad entre encuestas poblacionales, superando la actual tendencia a incluir decenas de preguntas en otras encuestas de índole regional o nacional (AU)

Introduction: Functional dependence is a growing problem, linked to increasing age, especially in industrialized countries. Population studies allow an approach to the magnitude of the problem. Objectives: Barber's questionnaire is a widely used instrument for the detection of risk of dependence, vulnerability or frailty in older adults. No works have been found that apply it in population-based studies, where, due to its simplicity, it could be useful. Methodology: The questionnaire was included in a Health Survey, with a representative sample (n = 1,882 subjects) of people aged 65 years or more, from a big city (Madrid, Spain) and the evidence of validity is presented based on the internal structure and the relationship with other variables of convergent and discriminant type. Results: A unifactorial solution was obtained, with adequate internal consistency according to several multivariate indicators. Significant differences were found by sex, both at the scale and item level. Significant correlations also appeared between the total test score and other variables, such as health-related quality of life, age, and sense of loneliness. A total of 58.1% of the sample obtained scores suggesting vulnerability (65.3% of the women). Conclusions: The results suggest the usefulness of the Barber questionnaire, as a reliable and valid test, to detect situations of frailty or vulnerability in older adults, which would facilitate comparability between population surveys, overcoming the current tendency to include dozens of questions in other regional or national surveys (AU)

[Influence of caudal anesthesia on the secretion of catecholamines in children]. / Influence de l'anesthésie caudale sur la sécrétion des catécholamines chez l'enfant.

Eighty-two children, class ASA I, between four months and 14 years of age, all undergoing elective subumbilical surgery, were randomly assigned to two groups: a control "halothane anesthesia" group (n = 35) and a 0.25% bupivacaine "caudal anaesthesia" group (n = 47). In the control group, there was a significant peroperative increase in heart rate, respiratory rate, systolic blood pressure and plasma adrenaline levels (p less than 0.05). There was no significant difference in the noradrenaline levels. In the "caudal anaesthesia" group, the haemodynamic response was less pronounced, this being concomitant with a decrease in adrenaline and noradrenaline levels (p less than 0.05 and p less than 0.001, respectively). During surgery, there were significant differences between the groups in heart rate, respiratory rate, noradrenaline levels (3 +/- 0,30 nmol X l-1 vs 1.68 +/- 0.18 nmol X l-1; p less than 0.001) and adrenaline levels (1.67 +/- 0,28 nmol X l-1 vs 0.78 +/- 0.08 nmol X l-1; p less than 0.01). It is concluded that the catecholamine response in children undergoing minor abdominal surgery has been blocked by caudal anaesthesia.

[Human immunodeficiency virus (HIV), thrombopenia and pregnancy]. / Virus de l'immunodéficience humaine (V.I.H.), thrombopénie et grossesse.

Three cases of thrombocytopenia in pregnant women are described. Two of these patients had an AIDS-like illness and the third one had AIDS. This HIV-associated change occurred in 8% of the complications of a consecutive series of 38 pregnant women who were positive for the HIV antibody test in the course of one year. A link with HIV was established after eliminating idiopathic pregnancy thrombocytopenic purpura and after eliminating every other viral cause for the thrombocytopenia. The normal myelogram speaks in favour of a peripheral origin for the platelet destruction. Treatment consisted in administering immunoglobulins intravenously in a continuous transfusion in doses of 0.04 g/kg per day. The method was effective in two cases. Three cesareans were carried out. In two cases the recovery was uncomplicated and in the third case the haemorrhagic syndrome developed immediately after delivery. This patient died 35 days after delivery. Fetal scalp blood or fetal cord blood could not be taken in any of these three cases. The newborn did not have thrombocytopenia at birth, but they did have anti-IVF antibodies and one of them developed and AIDS-like syndrome. The time interval has not been long enough to assess the further development in the two other cases. The survivors are being followed up with a threefold assessment of the blood picture, the immunological state and the virology. This is being done on the two surviving mothers and the three infants.

[Comparison of propanidid with propofol for dental surgery of short or medium duration]. / Comparaison propanidide-propofol en chirurgie stomatologique de courte ou moyenne durée.

The properties of propofol in emulsion given by continuous intravenous infusion to spontaneously breathing patients have been well studied. Thirty randomized voluntary premedicated patients undergoing dental extraction were anaesthetized with propofol (2.5 mg X kg-1 IVD, and 9 mg X kg-1 X h-1) or with propanidid (9 mg X kg-1 IVD, and 60 mg X kg-1 X h-1), supplemented with nitrous oxide in oxygen and fentanyl. Induction, maintenance and recovery times had the same characteristics. Highly significant differences occurred between the two groups regarding the increase in heart rate, apnoea and recovery time. This study showed that propofol was an eminently suitable agent for continuous intravenous anaesthesia in spontaneously breathing patients for dental surgery.

[Practical approach to complex acid-base disorders using a slide rule]. / Approche pratique des désordres acidobasiques complexes grâce à l'utilisation d'une réglette.

Diagnosis of mixed acid-base disturbances is often difficult. Nowadays it depends on biochemical and statistical interpretation, coupled with clinical data. The acid-base slide-rule is a useful tool to carry out this five step procedure, which it simplifies, giving rapidly at the patient's bed-side an objective support for the diagnosis of acid-base disturbances.