ABSTRACT
Coronavirus disease (COVID-19) is a critical and potentially fatal condition. The nutritional status affects the evolution and clinical outcome throughout the disease course among factors influencing the patient prognosis. In patients with cancer, the Patient-Generated Subjective Global Assessment (PG-SGA) is the preferred instrument for assessing the nutritional status. The aim of this retrospective cross-sectional study was to evaluate the impact of the nutritional status on the clinical outcome of patients with COVID-19 undergoing cancer treatment. We enrolled 52 patients with cancer under outpatient follow-up who had been diagnosed with COVID-19 during the cancer treatment course. The PG-SGA instrument revealed age (p = 0.045) and nutritional status (p = 0.042) before infection as the main risk factors of death from COVID-19. In addition, the risk of mortality due to COVID-19 increased with the degree of malnutrition. Twelve (23.1%) of the 52 patients showed no negative effects related to COVID-19, and age below 65 years was considered to be a protective factor.
Subject(s)
COVID-19 , Malnutrition , Neoplasms , Humans , Aged , Nutritional Status , Retrospective Studies , Cross-Sectional Studies , Nutrition Assessment , COVID-19/complications , Malnutrition/diagnosis , Neoplasms/complications , Neoplasms/therapyABSTRACT
An autochthonous case of visceral leishmaniasis is reported in a dog (Canis familiaris) as an apparently natural infection in a non-endemic area. DNA obtained from spleen and liver samples produced the expected fragment in a Leishmania-specific rDNA-based nested-PCR assay. The PCR product, a 490 bp fragment, was sequenced and the nucleotide sequence was identical to that of Leishmania (Leishmania) infantum chagasi. These results are surprising since no autochthonous human or canine cases of visceral leishmaniasis have ever been reported in this municipality. This case suggests that natural transmission of this disease is occurring in this area.
Subject(s)
Dog Diseases/epidemiology , Leishmaniasis, Visceral/epidemiology , Animals , Brazil/epidemiology , DNA, Protozoan/genetics , Dog Diseases/parasitology , Dogs , Female , Leishmaniasis, Visceral/veterinary , Polymerase Chain ReactionABSTRACT
An autochthonous case of visceral leishmaniasis is reported in a dog (Canis familiaris) as an apparently natural infection in a non-endemic area. DNA obtained from spleen and liver samples produced the expected fragment in a Leishmania-specific rDNA-based nested-PCR assay. The PCR product, a 490 bp fragment, was sequenced and the nucleotide sequence was identical to that of Leishmania (Leishmania) infantum chagasi. These results are surprising since no autochthonous human or canine cases of visceral leishmaniasis have ever been reported in this municipality. This case suggests that natural transmission of this disease is occurring in this area.
Caso autóctone de leishmaniose visceral é relatado em cão (Canis familiaris), aparentemente em área não endêmica. DNA obtido a partir de amostras do baço e fígado foram submetidos a nested-PCR baseada no rDNA específico de Leishmania. Os produtos das PCR foram sequenciados e os 490 pares de base foram idênticos a Leishmania (Leishmania) infantum chagasi. Esses resultados são surpreendentes, uma vez que, nenhum caso autóctone canino ou humano de leishmaniose visceral havia sido relatado neste município. Esse caso sugere que a transmissão natural da doença está ocorrendo nesta área.
Subject(s)
Animals , Dogs , Female , Dog Diseases/epidemiology , Leishmaniasis, Visceral/epidemiology , Brazil/epidemiology , DNA, Protozoan/genetics , Dog Diseases/parasitology , Leishmaniasis, Visceral/veterinary , Polymerase Chain ReactionABSTRACT
Avaliou-se a prevalência de oocistos de Cryptosporidium parvum em amostras de fezes de 459 bezerros com até 30 dias de idade e em amostras de água e piso dos bezerreiros de 33 propriedades leiteiras na regiäo de Araçatuba-Estado de Säo Paulo. A maior porcentagem de excreçäo de oocistos foi verificada em bezerros com faixa etária variando entre oito e 14 dias de idade (14,5 por cento) sendo, a menor taxa (6,4 por cento), detectada no grupo de animais mais velhos (22 a 30 dias de vida). Observaram-se, na amostragem total, valores positivos aproximados de 10,26 por cento pelo ensaio de imunoadsorçäo enzimática e de 12,4 por cento pelo teste de Sheather. As amostras de água foram negativas e duas de solo positivas.
