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Ann Fr Anesth Reanim ; 33(3): 176-7, 2014 Mar.
Article in French | MEDLINE | ID: mdl-24440731

ABSTRACT

Patients who are given a single dose of succinylcholine normally undergo a short-acting depolarizing phase I neuromuscular block but rarely a phase II block. Prolonged neuromuscular blockade occurs after a single dose of succinylcholine in case of genetically determined abnormal plasma butyrylcholinesterase activity. It is mandatory to use monitoring to detect this side effect. We report a case of a patient with abnormal plasma butyrylcholinesterase activity undergoing a six-hour prolonged neuromuscular phase II block, after a single dose of succinylcholine.


Subject(s)
Neuromuscular Blockade/adverse effects , Neuromuscular Depolarizing Agents/adverse effects , Succinylcholine/adverse effects , Adult , Butyrylcholinesterase/blood , Butyrylcholinesterase/genetics , Humans , Male , Monitoring, Physiologic , Mutation/genetics
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