ABSTRACT
The present article is an update of the literature on fungemia in onco-hematologic patients. A multidisciplinary group of Spanish physicians with an interest in this field selected the most important papers published lately. Papers from the fields of epidemiology, risk factors, pathogenesis, diagnosis, outcome, prevention and treatment are discussed. Important aspects of these studies include the assessment of different strategies in the management of fever in neutropenic patients. Moreover, early identification of patients at risk of fungal infections, as well as identification of patients at risk for fluconazole-resistant strains are topics of increasing interest.
Subject(s)
Fungemia , Hematology/trends , Medical Oncology/trends , Antifungal Agents/therapeutic use , Drug Resistance, Fungal , Fungemia/complications , Fungemia/diagnosis , Fungemia/drug therapy , Fungemia/epidemiology , Fungemia/prevention & control , Hematologic Diseases/complications , Humans , Immunocompromised Host , Neoplasms/complicationsABSTRACT
El trabajo que se presenta es una revisión de la bibliografía reciente más relevante del último año publicadaen relación con la funginemia en pacientes oncohematológicos. Un grupo multidisciplinar compuesto pordiferentes especialistas españoles con interés en este campo revisan los artículos más novedosos. Los trabajospertenecen a áreas de epidemiología, factores de riesgo, patogénesis, diagnóstico, evolución, prevencióny tratamiento. Se analizan diferentes aspectos, incluyendo estrategias del manejo de la fiebre en el pacienteneutropénico. La identificación precoz de factores de riesgo de infección fúngica, así como de los factoresde riesgo de infección por cepas resistentes a fluconazol es objetivo de especial interés (AU)
The present article is an update of the literature on fungemia in onco-hematologic patients. Amultidisciplinary group of Spanish physicians with an interest in this field selected the most importantpapers published lately. Papers from the fields of epidemiology, risk factors, pathogenesis, diagnosis,outcome, prevention and treatment are discussed. Important aspects of these studies include theassessment of different strategies in the management of fever in neutropenic patients. Moreover, earlyidentification of patients at risk of fungal infections, as well as identification of patients at risk forfluconazole-resistant strains are topics of increasing interest (AU)