ABSTRACT
Excellent outcomes of angioplasty/stenting for the post-thrombotic syndrome (PTS) have been reported, notably regarding objective criteria in the vast French SFICV cohort. Differences may exist between patient-reported and objective outcomes. We investigated this possibility by using validated scales because significative correlations are discordant in the literature between patency and patient-reported characteristics. Patient-reported outcomes seem to be a more consistent tool than radiologic patency for the diagnosis and follow-up of patients displaying PTS. We retrospectively reviewed the Villalta scale and 20-item ChronIc Venous dIsease quality-of-life Questionnaire (CIVIQ-20) scores recorded after endovascular stenting for PTS at 14 centres in France in 2009-2019. We also collected patency rates, pre-operative post-thrombotic lesion severity, and the extent of stenting. We performed multivariate analyses to identify factors independently associated with improvements in each of the two scores. The 539 patients, including 324 women and 235 men, had a mean age of 44.7 years. The mean Villalta scale improvement was 7.0 ± 4.7 (p < 0.0001) and correlated with the thrombosis sequelae grade and time from thrombosis to stenting. The CIVIQ-20 score was available for 298 patients; the mean improvement was 19.2 ± 14.8 (p < 0.0001) and correlated with bilateral stenting, single thrombosis recurrence, and single stented segment. The objective gains demonstrated in earlier work after stenting were accompanied by patient-reported improvements. The factors associated with these improvements differed between the Villalta scale and the CIVIQ-20 score. These results proved that clinical follow-up with validated scores is gainful in patients treated for PTS thanks to a mini-invasive procedure.
ABSTRACT
PURPOSE: To assess the results of endovascular treatment in a large population of patients suffering from post-thrombotic syndrome (PTS) due to iliocaval occlusive disease. METHODS: In this retrospective multi-center study, 698 patients treated by stenting for PTS in 15 French centers were analyzed. Primary, primary assisted, and secondary patency rates were assessed, and clinical efficacy was evaluated using Villalta and Chronic Venous Insufficiency Questionnaire in 20 questions (CIVIQ-20) scores. Outcomes were compared against pre-operative CT-based severity of the post-thrombotic lesions in the thigh (4 grades). RESULTS: Technical success, defined as successful recanalization and stent deployment restoring rapid anterograde flow in the targeted vessel, was obtained in 668 (95.7%) patients with a complication rate of 3.9%. After a mean follow-up of 21.0 months, primary patency, primary assisted patency, and secondary patency were achieved in 537 (80.4%), 566 (84.7%), and 616 (92.2%) of the 668 patients, respectively. Venous patency was strongly correlated to the grade of post-thrombotic changes in the thigh, with secondary patency rates of 96.0%, 92.9%, 88.4%, and 78.9%, respectively, for grades 0 to 3 (p = .0008). The mean improvements of Villalta and CIVIQ-20 scores were 7.0 ± 4.7 points (p < .0001) and 19.1 ± 14.8 points (p < .0001), respectively. CONCLUSION: Endovascular stenting as a treatment option for PTS due to chronic iliocaval venous occlusion generates a high technical success, low morbidity, high midterm patency rate, and clinical improvement. Venous patency was strongly correlated to the severity of post-thrombotic lesions in the thigh.
Subject(s)
Endovascular Procedures , Postthrombotic Syndrome , Femoral Vein , Humans , Iliac Vein , Postthrombotic Syndrome/diagnostic imaging , Retrospective Studies , Stents , Treatment Outcome , Vascular PatencySubject(s)
Glomus Tumor/therapy , Laser Therapy , Neoplasms, Multiple Primary/therapy , Skin Neoplasms/therapy , Buttocks , Child , Female , Humans , Male , Treatment Outcome , Young AdultABSTRACT
The authors report three cases of transient and recurrent paraplegia due to compression of the second right lumbar artery by the diaphragmatic crus. Circumstances of appearance are suggestive when paraplegia occurs in dorsolumbar hyperlordosis and low cardiac output is an associated hemodynamic risk factor. Selective medullary arteriography is indispensable for diagnosis and can demonstrate three signs: an anterior spinal dorsolumbar artery (artery of Adamkiewicz) that does not descend to the conus medullaris; posterior spinal arteries arising from the second lumbar arteries that vascularize the conus medullaris; existence of a tight stenosis on the second right lumbar artery that is aggravated during dynamic maneuvers. Section of the right diaphragmatic crus and release of the second right lumbar artery from the aorta to the fibrous arcade of the psoas permits definitive cure of symptoms.
Subject(s)
Diaphragm , Paraplegia/etiology , Spinal Cord Ischemia/complications , Adult , Diaphragm/anatomy & histology , Humans , Male , Middle AgedABSTRACT
In this report the authors describe the endovascular treatment of dural arteriovenous fistulas (DAVFs) through transcranial puncture of the feeding arteries. Four patients had DAVFs that were fed by occipital arteries (OAs) that supplied blood to the intracranial meningeal arteries via the transcranial branches and coursed through the parietal and mastoid foramina. Due to the excessive tortuosity of the OA, conventional endovascular navigation had failed in all cases. Transcranial puncture of the meningeal feeding arteries was performed through the parietal or mastoid foramen, allowing navigation with a microcatheter until the level of the shunts. Complete cure of the DAVF was attained in all patients after injection of acrylic glue.
Subject(s)
Central Nervous System Vascular Malformations/therapy , Craniotomy/methods , Embolization, Therapeutic/methods , Punctures/methods , Adult , Aged , Central Nervous System Vascular Malformations/diagnostic imaging , Cerebral Angiography , Cerebral Arteries/diagnostic imaging , Cyanoacrylates/administration & dosage , Female , Humans , Image Processing, Computer-Assisted , Imaging, Three-Dimensional , Iodized Oil/administration & dosage , Male , Mastoid , Middle Aged , Occipital Lobe/blood supply , Parietal Bone , Tissue Adhesives/administration & dosage , Tomography, X-Ray ComputedABSTRACT
The pathogenesis of both intracranial aneurysms and spontaneous cervical artery dissection may be related to an underlying vasculopathy. Seven cases of spontaneous cervical artery dissection in the course of ruptured berry aneurysms are reported here.
Subject(s)
Carotid Artery, Internal, Dissection/complications , Carotid Artery, Internal, Dissection/diagnostic imaging , Subarachnoid Hemorrhage/complications , Subarachnoid Hemorrhage/diagnostic imaging , Vertebral Artery Dissection/complications , Vertebral Artery Dissection/diagnostic imaging , Adult , Aged , Carotid Artery, Internal, Dissection/physiopathology , Causality , Cerebral Angiography , Cerebral Arteries/pathology , Cerebral Arteries/physiopathology , Female , Humans , Hypertension/complications , Hypertension/pathology , Hypertension/physiopathology , Intracranial Aneurysm/complications , Intracranial Aneurysm/diagnosis , Male , Middle Aged , Stress, Physiological/pathology , Stress, Physiological/physiopathology , Subarachnoid Hemorrhage/physiopathology , Sympathetic Nervous System/physiopathology , Tomography, X-Ray Computed , Vertebral Artery Dissection/physiopathologyABSTRACT
Stent implantation was performed on two patients to treat chronic dissecting aneurysms of the upper cervical internal carotid artery. Treatment was decided because of the youth of the patients, their medical history of subarachnoid hemorrhage, and the angiographic findings associated with the dissection. Normal arteriographic morphology was obtained after deployment of a single self-expandable stent.
Subject(s)
Aortic Dissection/surgery , Carotid Artery, Internal, Dissection/surgery , Stents , Adult , Aortic Dissection/diagnostic imaging , Carotid Artery, Internal, Dissection/diagnostic imaging , Chronic Disease , Female , Humans , Male , RadiographyABSTRACT
Recanalization of the basilar artery is not always achieved with intraarterial fibrinolysis. We report two cases of thromboaspiration in the basilar artery in which recanalization with fibrinolysis was successful. Thromboaspiration requires favorable anatomy and a fresh nonadhesive clot. It reduces the time for recanalization, has no hemorrhagic risk, and may prevent distal clot migration. Thromboaspiration may be attempted as an adjunct or alternative to intraarterial fibrinolysis for basilar artery recanalization.