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HLA-G polymorphism and breast cancer.
Rolfsen, G B; Castelli, E C; Donadi, E A; Duarte, R A; Soares, C P.
Int J Immunogenet ; 41(2): 143-8, 2014 Apr.
Article in English | MEDLINE | ID: mdl-24164707

ABSTRACT

The aim of this study was to explore a possible influence of the HLA-G coding polymorphisms on the susceptibility to breast cancer development in Brazilian subjects; however, none of the HLA-G variation sites evaluated was influencing breast cancer susceptibility indicating that the variation in the HLA-G coding region is not a risk factor for breast cancer.


Subject(s)
Breast Neoplasms/genetics , HLA-G Antigens/genetics , Adult , Alleles , Brazil , Breast Neoplasms/immunology , Case-Control Studies , Female , Genetic Predisposition to Disease , Genotype , Humans , Middle Aged , Polymorphism, Single Nucleotide , Risk Factors
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